Nucleolus targeting by negative strand RNA viruses. Negative strand viruses (NSVs) include diverse animal pathogens that represent significant threats to Australian livestock industries and access to export markets. The project aims to investigate the interface formed by NSVs with cellular nucleoli in order to determine roles in viral manipulation of cell biology during infection. This project hopes to address a major gap in knowledge in virology regarding the fundamental biology of NSVs, and is ....Nucleolus targeting by negative strand RNA viruses. Negative strand viruses (NSVs) include diverse animal pathogens that represent significant threats to Australian livestock industries and access to export markets. The project aims to investigate the interface formed by NSVs with cellular nucleoli in order to determine roles in viral manipulation of cell biology during infection. This project hopes to address a major gap in knowledge in virology regarding the fundamental biology of NSVs, and is expected to redefine our understanding of the virus-host interactions formed by these important pathogens. By determining the mechanisms of NSV-nucleolus interaction, the project plans to also provide important information for the development of new vaccines/therapeutics for livestock to combat NSVs that target nucleoli.Read moreRead less
Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the struct ....Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the structural basis for their activity. We will do this by chemically synthesising peptides with selected residues mutated to determine their effects on activity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100133
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
National Facility for Physical Blast Simulation (NFPBS). Recent terrorist attacks employing large quantities of high explosives have prompted the international demand for experimental investigation of civil infrastructure response to shock wave loadings. The National Facility for Physical Blast Simulation (NFPBS) is one of only a few in the world that are suitable for conducting experimental research via a physically generated blast approach.
A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing ....A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing pad which can be used as the next generation combat helmet liners and accessories. The novel high-performance energy absorption system will have a wide range of direct applications in future personal armour, as well as sports gears and elderly healthcare products.Read moreRead less
Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expecte ....Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expected to deliver new experimental data on novel surface materials exposed to a hypersonic flow environment and computer models that can simulate their cooling effect. This investigation will contribute towards enabling technologies for sustained hypersonic flight by overcoming critical head load limitations.Read moreRead less
Emerging technologies of warfare as a challenge to the law of armed conflict: cyber-attacks, robotics and nanotechnology. In order to reduce suffering in war, international law places limits on the ways in which the adversary can be harmed. This project will assess how the law fares in dealing with emerging technologies, such as hostile uses of computer networks, robotics and nanotechnology. It will provide guidance to policy makers on how the law can be improved.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100106
Funder
Australian Research Council
Funding Amount
$780,000.00
Summary
A global fireball observatory. This project aims to expand the Desert Fireball Network (DFN) and build a Global Fireball Observatory. Nearly everything known about the origin and evolution of the solar system comes from analysis of meteorite falls, but scientists have almost no constraint on where they come from. This project will address this constraint by tracking hundreds of meteorite falls, and pinpointing each one’s origin in the solar system. Benefits include capitalising on the innovation ....A global fireball observatory. This project aims to expand the Desert Fireball Network (DFN) and build a Global Fireball Observatory. Nearly everything known about the origin and evolution of the solar system comes from analysis of meteorite falls, but scientists have almost no constraint on where they come from. This project will address this constraint by tracking hundreds of meteorite falls, and pinpointing each one’s origin in the solar system. Benefits include capitalising on the innovations and technologies that underpinned the DFN, and leveraging a NASA partnership for administrative support and advanced instrumentation development. Tracking for space situational awareness is also expected to benefit Australian national security.Read moreRead less
Wind Tunnel Testing of a Hypersonic Plasma Engine. This project intends to evaluate an electric engine that is capable of speeds in excess of 10000 km/hr, for access to space and responsive surveillance in our region. The expertise of Lockheed Martin, Lockheed Martin Australia, the University of Qld and DST Group are to be combined to complete experimental and theoretical evaluations of an air-breathing plasma engine that is capable of out-performing rockets and scramjets. US Air Force Research ....Wind Tunnel Testing of a Hypersonic Plasma Engine. This project intends to evaluate an electric engine that is capable of speeds in excess of 10000 km/hr, for access to space and responsive surveillance in our region. The expertise of Lockheed Martin, Lockheed Martin Australia, the University of Qld and DST Group are to be combined to complete experimental and theoretical evaluations of an air-breathing plasma engine that is capable of out-performing rockets and scramjets. US Air Force Research Laboratory results will also be compared and shared. This project provides opportunities for young Australian researchers to be participate and lead an exciting new field of propulsion. It is anticipated that the program will be the foundations to future flight demonstrations from Woomera, Australia.Read moreRead less
Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also ....Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also have significant spillover benefits into other complex system domains, where computational tools can be used to aid in design leading to high embedded-IP products for Australian industry. Furthermore, the proposal encompasses a strong research training aspect, with graduates exposed to leading edge industry and academia.Read moreRead less
ARC Centre of Excellence for Engineered Quantum Systems. This Centre aims to build sophisticated quantum machines to harness the quantum world for the future health, economy, environment and security of Australian society. It intends to pioneer the designer quantum materials, engines and imaging systems at the heart of these machines. It also solves the most challenging research problems at the interface of basic quantum physics and engineering. The Centre will work with industry partners to tra ....ARC Centre of Excellence for Engineered Quantum Systems. This Centre aims to build sophisticated quantum machines to harness the quantum world for the future health, economy, environment and security of Australian society. It intends to pioneer the designer quantum materials, engines and imaging systems at the heart of these machines. It also solves the most challenging research problems at the interface of basic quantum physics and engineering. The Centre will work with industry partners to translate these research discoveries into practical applications and devices. It will train scientists in research, innovation, and entrepreneurship, which is expected to affect Australia’s high-tech economy.Read moreRead less