Methylation-sensitive T Cell Genes And Childhood Food Allergy.
Funder
National Health and Medical Research Council
Funding Amount
$461,232.00
Summary
Australia has the highest reported prevalence food allergy in the world. Despite this, little is known about how allergy develops. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of food challenge proven food allergy with assessment of immune functioning & cutting edge genomics, to extensively characterise the pathways leading to food allergy in children.
Methylation Sensitive Genes And The Transition To Allergic Disease: A Twin Study
Funder
National Health and Medical Research Council
Funding Amount
$493,843.00
Summary
Australia has amongst the highest reported prevalence allergic conditions (including asthma) in the world. Despite this, little is known about how these conditions arise. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of a unique collection of identical twins where one of a pair is sensitive to house dust mite, with cutting edge genomics, to characterise the pathways leading to allergy in ....Australia has amongst the highest reported prevalence allergic conditions (including asthma) in the world. Despite this, little is known about how these conditions arise. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of a unique collection of identical twins where one of a pair is sensitive to house dust mite, with cutting edge genomics, to characterise the pathways leading to allergy in children.Read moreRead less
Early Nutrition, Epigenetics And Developmental Outcomes In Children.
Funder
National Health and Medical Research Council
Funding Amount
$550,093.00
Summary
Increasing evidence demonstrates that early nutrition, including in pregnancy, has long lasting programming effects on later health of children. Evidence implicates epigenetics (literally ‘above DNA’) in mediating these effects. The most convincing data exists for obesity and related disorders such as metabolic syndrome, diabetes, and heart disease. The focus of this project is on understanding how ‘epigenetic’ mechanisms are influencing the way our genes function to cause these disorders.
Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess c ....Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess chemical fate on a national level by linking sales/use with fate and release from wastewater treatment plants and assess treatment efficiency at >100 plants around Australia. The project expects to provide insight for government, wastewater managers and industry into hazards that may affect environmental and human health.Read moreRead less
In-situ electrochemical generation of caustic and oxygen from sewage for emission control in sewers. This project aims to deliver an innovative technology that controls the emission of notorious compounds from sewer networks using chemicals directly produced from sewage, with electricity being the input. Compared to existing methods, this technology provides a much safer and more environmentally friendly solution, at less than 50 per cent of the cost.
Industrial Transformation Research Hubs - Grant ID: IH190100009
Funder
Australian Research Council
Funding Amount
$3,317,500.00
Summary
ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste ....ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste into valuable materials and products, including metallic alloys, oxides and carbon. Expected outcomes include industry adoption of commercially viable technology and processes where low value or complex waste is reformed into higher value materials, creating jobs and significant environmental and social benefits.Read moreRead less
Synthesis of Activated Carbon Supported Zero Valent Iron Nanoparticles and Application to Contaminant Degradation in Benthic Sediments. Sediment contamination is a major problem in harbours and estuaries around Australia. For example, in Sydney Harbour, a total fishing ban has been implemented as a result of excessive levels of dioxins and benzofurans in fish tissues. There is also concern at the possibility of large scale contamination of Botany Bay as a result of historic industrial activity a ....Synthesis of Activated Carbon Supported Zero Valent Iron Nanoparticles and Application to Contaminant Degradation in Benthic Sediments. Sediment contamination is a major problem in harbours and estuaries around Australia. For example, in Sydney Harbour, a total fishing ban has been implemented as a result of excessive levels of dioxins and benzofurans in fish tissues. There is also concern at the possibility of large scale contamination of Botany Bay as a result of historic industrial activity around the Bay. While dredging and on-land treatment of sediments is being adopted at the most severely contaminated sites, the cost of this approach is exorbitant. For sites where removal of contaminated sediments cannot be justified, the approach proposed in this study of a technology that entraps contaminants and enhances their in situ biodegradation is potentially a way forward.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100922
Funder
Australian Research Council
Funding Amount
$408,490.00
Summary
Foresight: Anticipatory decision-making in water resource management. Long-term planning is vital to secure Australia’s water resources in the face of environmental disruption. This project aims to contribute to sustainable and equitable water management by examining the efficacy of anticipatory decision-making approaches. Qualitative research will be used to examine how scientific knowledge is used or contested in water reform within the Murray-Darling Basin. Intended outcomes include improved ....Foresight: Anticipatory decision-making in water resource management. Long-term planning is vital to secure Australia’s water resources in the face of environmental disruption. This project aims to contribute to sustainable and equitable water management by examining the efficacy of anticipatory decision-making approaches. Qualitative research will be used to examine how scientific knowledge is used or contested in water reform within the Murray-Darling Basin. Intended outcomes include improved capacities to plan for future change and establishing anticipatory decision-making within Australian natural resource management. This should provide significant benefits based on an integrated approach to science and decision-making that addresses trade-offs between stakeholders to identify shared action pathways.Read moreRead less
Ethics, responsibility and the carbon budget. This project aims to provide a rigorous ethical framework for dividing the world’s remaining ‘carbon budget’ (CB). In order to avoid climate change the world must drastically limit its emissions of greenhouse gases. The project will develop a new analysis of how our assumptions concerning risk and harm shape conception of the CB. It will also provide a new understanding of how future emission rights should be allocated given that countries have emitt ....Ethics, responsibility and the carbon budget. This project aims to provide a rigorous ethical framework for dividing the world’s remaining ‘carbon budget’ (CB). In order to avoid climate change the world must drastically limit its emissions of greenhouse gases. The project will develop a new analysis of how our assumptions concerning risk and harm shape conception of the CB. It will also provide a new understanding of how future emission rights should be allocated given that countries have emitted vastly different quantities of greenhouse gases in the past. The project will analyse how the CB will impact the climate transition plans of countries such as Australia. The project will thus bring significant new research in philosophy to bear on a practical issue.Read moreRead less
Cover crops that decrease phosphorus (P) transport from agricultural soils by increasing the efficiency of P fertiliser application. The aim of this project is to develop cover crop practices for the heavily fertilised potato cropping soils of the Robertson district that will minimise erosion and runoff of water potentially rich in phosphorus (P), thereby resulting in significant improvements in the environmental management of this sensitive catchment area. The cover crops will: (i) improve infi ....Cover crops that decrease phosphorus (P) transport from agricultural soils by increasing the efficiency of P fertiliser application. The aim of this project is to develop cover crop practices for the heavily fertilised potato cropping soils of the Robertson district that will minimise erosion and runoff of water potentially rich in phosphorus (P), thereby resulting in significant improvements in the environmental management of this sensitive catchment area. The cover crops will: (i) improve infiltration, decrease erosion, and off-site transport of P; (ii)increase access to accumulated soil P, making it available to a subsequent potato crop, thus decreasing the P loading of the soil; and (iii) have a biofumigation effect that will reduce the use of soil fumigants.
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