Continuous tooth replacement in mammals: revealing the fundamental processes in tooth generation and movement. This project will investigate how molar teeth are made in mammals by examining the nabarlek, or little rock-wallaby, which is one of a handful of mammals that is able to regenerate new molars throughout its life. These new teeth migrate through the bone in order to move into the correct position in the mouth. By investigating two well-studied organisms, the mouse and the tammar wallaby, ....Continuous tooth replacement in mammals: revealing the fundamental processes in tooth generation and movement. This project will investigate how molar teeth are made in mammals by examining the nabarlek, or little rock-wallaby, which is one of a handful of mammals that is able to regenerate new molars throughout its life. These new teeth migrate through the bone in order to move into the correct position in the mouth. By investigating two well-studied organisms, the mouse and the tammar wallaby, as well as the nabarlek itself, the developmental processes and genes involved in molar generation and movement will be revealed. This project will integrate findings in regenerative medicine, evolutionary biology, materials engineering and palaeontology to reveal the mechanisms and origins of this astounding capability.Read moreRead less
Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the rel ....Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the release of cryptic genetic variation that can allow novel morphologies to evolve in new environments. The project expects to provide further understanding of how species may potentially adapt to environmental stresses in the future, including climate change.Read moreRead less
Is regressive evolution associated with loss of gene function in subterranean animals? This project aims to investigate a fundamental biological process: the evolutionary basis for how non-functional characters, such as eyes in subterranean animals, are lost. It will use a unique model system based on eyeless water beetles, and utilise novel new genomic tools to test whether loss of characters results from gene inactivation.
How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex ....How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex traits.Read moreRead less
Capturing Proteus: 65 million years of ecosystem change revealed through evolution of Proteaceae in Australasia. By assessing past changes in the iconic Australian plant family Proteaceae, this research will show how the Australasian vegetation has responded to 65 million years of profound landscape and climate changes. This knowledge from the past will give important insights into how ecosystems can be expected to change under future climate scenarios.
Comparative Paleogenomics of the Arctic Tundra Ecosystem: the genetic response of plants and animals to climate change. This project will use DNA from deep-frozen seeds and bones 100,000 years old to record how species respond to climate change - by adapting and surviving or by shifting ranges and moving. Very large numbers of genes will be examined to identify changes across the genomes of four plant and two animal species, and contrast the responses to major climatic shifts.
Adapting to a changing world: mothers as drivers of evolutionary change. This project will improve our understanding of how organisms will adapt to the unprecedented speed and magnitude of human-induced environmental change. By identifying how mothers modify their offspring to better match the prevailing environment, it will address the role of mothers in directing and accelerating adaptation in our changing world.
Primary producers; morphological flexibility under environmental constraints. Climate change impacts on phytoplankton that uptake nutrients for incorporation into food webs including marine mammals and fish. This project will study the morphological flexibility of diatoms to reveal principles underlying nutrient uptake under different climatic scenarios.
The physiology of biome shifts and macroevolutionary change: how did Australian skinks colonise the arid zone so successfully? This project will examine two of Australia's most diverse lizard lineages, Lerista and Ctenotus, and will identify the physiological and morphological traits that enabled them to adaptively radiate within the arid zone. It will highlight those traits likely to be adaptive for environments predicted to become widespread under climate change.
Resolving how five million years of dramatic climatic changes shaped Australia's unique fauna. Australia’s biota is a product of its unique heritage, tectonic history and most especially its climate. Over the past five million years it has been beset by a series of intense climatic shifts driven by a combination of global and regional factors. This project will be the first to track faunal responses to environmental changes across this critical interval. It will establish the dynamics of the ori ....Resolving how five million years of dramatic climatic changes shaped Australia's unique fauna. Australia’s biota is a product of its unique heritage, tectonic history and most especially its climate. Over the past five million years it has been beset by a series of intense climatic shifts driven by a combination of global and regional factors. This project will be the first to track faunal responses to environmental changes across this critical interval. It will establish the dynamics of the origin of the modern southern vertebrate fauna, analysing changes in diversity, diet and community structure. By exploring associations between phases of faunal turnover and key climatic transitions, it will bring a Southern Hemisphere perspective to evolutionary models of Cenozoic faunal change largely generated to date from Northern Hemisphere data.Read moreRead less