A New framework to improve human-robot interaction in financial markets. This project aims to investigate the interaction of humans with robots (automated, algorithmic traders) in financial markets. It will build a novel environment based on controlled experiments within the context of financial markets. It is expected to discover how market participants choose to engage robots, and when and why robots are disengaged. The project will also investigate how the use of robots affects price behavio ....A New framework to improve human-robot interaction in financial markets. This project aims to investigate the interaction of humans with robots (automated, algorithmic traders) in financial markets. It will build a novel environment based on controlled experiments within the context of financial markets. It is expected to discover how market participants choose to engage robots, and when and why robots are disengaged. The project will also investigate how the use of robots affects price behaviour, and efficiency of allocation. This will provide significant benefits, such as enhancing Australia’s capacity for the scientific study of financial markets and for developing financial technology using an experimental method.Read moreRead less
Reduction Of Chronic Post-surgical Pain With Ketamine - ROCKet Study
Funder
National Health and Medical Research Council
Funding Amount
$4,823,395.00
Summary
Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.
Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
Time Delay, Externalities and Attitudes Toward Taxation. Public attitudes toward a policy have a significant impact on its effectiveness. The aim of this project is to investigate the determinants of public attitudes for incentive-based institutions, particularly taxes, by highlighting the importance of considering the intertemporal properties of taxation: when costs and benefits of taxation occur at different times. This project is designed to be a controlled study of how and why public attitud ....Time Delay, Externalities and Attitudes Toward Taxation. Public attitudes toward a policy have a significant impact on its effectiveness. The aim of this project is to investigate the determinants of public attitudes for incentive-based institutions, particularly taxes, by highlighting the importance of considering the intertemporal properties of taxation: when costs and benefits of taxation occur at different times. This project is designed to be a controlled study of how and why public attitudes towards taxation are influenced by the temporal structure of the externalities that the taxes are meant to control. The anticipated goal is to inform the design of institutions that the public will accept and, more generally, improve the understanding of intertemporal decision-making in environments with delayed externalities.Read moreRead less
Market Design for the Reallocation of Land. This fellowship uses laboratory and lab-in-the-field experiments to explores how market design can be used to develop combinatorial exchanges that allow participants to exchange packages of land. Allowing for package bids can facilitate trade in situations where owning one piece of land increases the value of adjacent land and where assembling contiguous pieces of land is important. Combinatorial exchanges have the potential to increase the productivit ....Market Design for the Reallocation of Land. This fellowship uses laboratory and lab-in-the-field experiments to explores how market design can be used to develop combinatorial exchanges that allow participants to exchange packages of land. Allowing for package bids can facilitate trade in situations where owning one piece of land increases the value of adjacent land and where assembling contiguous pieces of land is important. Combinatorial exchanges have the potential to increase the productivity of agriculture land in both Australia and developing countries, encourage urban redevelopment, and help the government secure land for infrastructure and environmental protection in a cost-effective way.Read moreRead less
The Therapeutic Role Of Complement Inhibition In ANCA Associated Glomerulonephritis
Funder
National Health and Medical Research Council
Funding Amount
$600,964.00
Summary
ANCA associated vasculitis is an inflammatory disease involving the kidney filters which is a major cause of chronic kidney failure. Current drugs to treat it are toxic. Less toxic treatments are required. In this study we will explore the potential for new treatments targeting complement (a normal blood protein involved in inflammation) to attenuate this disease in mice. We hope to define the role of complement in this disease and the benefits of inhibiting it before we use it in humans.
Molecular Targets Of Amino Acid/neurotransmitter Conjugates Of Fatty Acids
Funder
National Health and Medical Research Council
Funding Amount
$846,390.00
Summary
This project investigates endogenous chemicals that affect cells important for detecting and responding to pain. We aim to discover how these compounds affect proteins important for nerve cell function, particularly proteins that have a prominent role in detecting and transmitting painful events. The compounds we examine are not themselves likely to be drugs, but future therapies may involve manipulating the levels of these chemicals in the body, or using drugs that mimic the activity of these c ....This project investigates endogenous chemicals that affect cells important for detecting and responding to pain. We aim to discover how these compounds affect proteins important for nerve cell function, particularly proteins that have a prominent role in detecting and transmitting painful events. The compounds we examine are not themselves likely to be drugs, but future therapies may involve manipulating the levels of these chemicals in the body, or using drugs that mimic the activity of these compounds.Read moreRead less
Spinal Cord Injury Pain: Understanding Mechanisms To Develop Treatments
Funder
National Health and Medical Research Council
Funding Amount
$597,675.00
Summary
Spinal cord injury has devastating effects on health and quality of life. Many of the major consequences of injury, such as chronic pain and loss of voluntary voiding, are "invisible" – i.e., they are not as visible as limitations of mobility. Our study aims to define the neurobiological changes that cause development of persistent pain after spinal cord injury and use pharmacological tools to attenuate the development of pain.
Posted prices, bargaining and auctions: an experimental examination. This project uses economic methods to investigate how trading institutions affect prices and efficiency. It examines markets with directed search: buyers visit sellers based on any information they have. Simultaneous buyer choices and sellers’ capacity constraints lead to “frictions” where not all profitable exchanges occur - more realistic than the usual “frictionless” assumption. The project will vary: whether sellers can pos ....Posted prices, bargaining and auctions: an experimental examination. This project uses economic methods to investigate how trading institutions affect prices and efficiency. It examines markets with directed search: buyers visit sellers based on any information they have. Simultaneous buyer choices and sellers’ capacity constraints lead to “frictions” where not all profitable exchanges occur - more realistic than the usual “frictionless” assumption. The project will vary: whether sellers can post prices in advance; and, whether and how negotiation occurs based on how many buyers (one vs two or more) visit a seller. The project will use results from auction, bargaining, game and search theories, and new analysis, to form predictions, which will be tested using experiments. The results should have implications for labour and competition policies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101014
Funder
Australian Research Council
Funding Amount
$349,785.00
Summary
Extending economic design to non-market settings: An experimental study of mechanism design with intention-based preferences. Mechanism design is the engineering side of economic theory, which starts with assumptions regarding human nature and builds economic systems to best maximise efficiency according to these assumptions. This project studies mechanism design in experimental settings where individuals exhibit a desire to be kind to those who have been kind to them and unkind to those who ha ....Extending economic design to non-market settings: An experimental study of mechanism design with intention-based preferences. Mechanism design is the engineering side of economic theory, which starts with assumptions regarding human nature and builds economic systems to best maximise efficiency according to these assumptions. This project studies mechanism design in experimental settings where individuals exhibit a desire to be kind to those who have been kind to them and unkind to those who have not. Such preferences are common in many non-market settings and can have dramatic effects on the efficiency of potential mechanisms. The ultimate goal of this project is to develop applied mechanisms that are robust to heterogeneity in such intention-based preferences and which can be used in bilateral exchange, contract design and many other non-market settings.Read moreRead less