Molecular definition of cellular states in the vascular endothelium. The endothelium is the main cell type forming blood vessels and spans across multiple cell states from stem/progenitor to a variety of terminally differentiated cells. How each of these cell states are defined at the molecular level is not known preventing the optimal formation and integration of blood vessels in bioengineered tissues. Using innovative single cell gene expression and chromatin accessibility studies combined wit ....Molecular definition of cellular states in the vascular endothelium. The endothelium is the main cell type forming blood vessels and spans across multiple cell states from stem/progenitor to a variety of terminally differentiated cells. How each of these cell states are defined at the molecular level is not known preventing the optimal formation and integration of blood vessels in bioengineered tissues. Using innovative single cell gene expression and chromatin accessibility studies combined with innovative analysis, we propose to define and validate each cell state at the molecular level.
This new knowledge would greatly enhance our ability to control the transition between cell states leading to a more widespread use of endothelial cells in bioengineering of tissues globally for many applications.
Read moreRead less
Robust Data-Driven Control for Safety-Critical Systems. This project aims to develop new approaches to controlling robotic and cyber-physical systems in safety-critical applications. This project expects to generate new knowledge in how to harness the power of machine learning for robot control, while guaranteeing safety and stability at all times. The outcomes of this project will be new algorithms and a deeper understanding of the interplay of data, learning, and models, as well as experimenta ....Robust Data-Driven Control for Safety-Critical Systems. This project aims to develop new approaches to controlling robotic and cyber-physical systems in safety-critical applications. This project expects to generate new knowledge in how to harness the power of machine learning for robot control, while guaranteeing safety and stability at all times. The outcomes of this project will be new algorithms and a deeper understanding of the interplay of data, learning, and models, as well as experimental validation on a surgical robot and a bipedal walking robot. This project will provide significant benefits by dramatically increasing the range of applications in which the power of machine learning can be safely applied to advance the capabilities and uptake of robotics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100021
Funder
Australian Research Council
Funding Amount
$440,154.00
Summary
Kesterite/Si Tandem Structure for Unassisted Overall Solar Fuel Production. This project aims to develop Kesterite/Si tandem device for photoelectrochemical carbon dioxide reduction to produce solar fuels. It is expected to reveal the photoelectrochemical mechanism of the p-n heterojunction, thereby promoting solar energy utilisation and greenhouse gas reduction. Expected outcomes include delivery of a high-performance kesterite photocathode for efficient CO2 reduction, a kesterite/Si tandem dev ....Kesterite/Si Tandem Structure for Unassisted Overall Solar Fuel Production. This project aims to develop Kesterite/Si tandem device for photoelectrochemical carbon dioxide reduction to produce solar fuels. It is expected to reveal the photoelectrochemical mechanism of the p-n heterojunction, thereby promoting solar energy utilisation and greenhouse gas reduction. Expected outcomes include delivery of a high-performance kesterite photocathode for efficient CO2 reduction, a kesterite/Si tandem device for overall unassisted solar fuel production, and an in-depth understanding of structure-performance correlation to guide future heterojunction photocathode design. This project should provide significant benefits in minimising fossil fuel consumption, increasing energy security, and expanding the clean energy industry.Read moreRead less
Control and learning for enhancing capabilities of quantum sensors. This project aims to develop new theories and algorithms to enhance capabilities in engineering quantum sensors from the perspective of systems and control. The project is significant because it is anticipated to advance key knowledge and provide systematic methods to enable achievement of high-precision sensing for wide applications, e.g., early disease detection, medical research, discovery of ore deposits and groundwater moni ....Control and learning for enhancing capabilities of quantum sensors. This project aims to develop new theories and algorithms to enhance capabilities in engineering quantum sensors from the perspective of systems and control. The project is significant because it is anticipated to advance key knowledge and provide systematic methods to enable achievement of high-precision sensing for wide applications, e.g., early disease detection, medical research, discovery of ore deposits and groundwater monitoring. The intended outcomes are fundamental theories, effective control and learning algorithms for achieving highly-sensitive sensors. These outcomes should make important contributions to and deliver new knowledge and skills for Australia's sensing industries, which could benefit Australia's economic growth.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101617
Funder
Australian Research Council
Funding Amount
$434,395.00
Summary
Re-engineering metallic-based nanostructures for carbon dioxide conversion. This project aims to fine-tune the interface of low-temperature liquid metals to produce functional hybrid nanomaterials for CO2 reduction. The expected outcomes of the projects are to develop fundamental knowledge on the integration of functional molecules on the bulk, core, and skin of liquid metals and their alloys. It intends to control the atomic arrangement of the elemental constituents, nucleation, as well as inte ....Re-engineering metallic-based nanostructures for carbon dioxide conversion. This project aims to fine-tune the interface of low-temperature liquid metals to produce functional hybrid nanomaterials for CO2 reduction. The expected outcomes of the projects are to develop fundamental knowledge on the integration of functional molecules on the bulk, core, and skin of liquid metals and their alloys. It intends to control the atomic arrangement of the elemental constituents, nucleation, as well as interaction and dissolution of organic/inorganic molecules in the interface and bulk of liquid metals. The anticipated outcomes of this project are to define a knowledge roadmap to exploit the untapped potentials of liquid metals in CO2 reduction, which would enable the production of the next generation of catalytic devices.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101068
Funder
Australian Research Council
Funding Amount
$454,554.00
Summary
Direct Electrolysis of Amine Captured CO2 for Producing Syngas. This project aims to develop electrolysis of amine captured carbon dioxide (CO2) technology to integrate CO2 capture and syngas production powered by renewable electricity. The aqueous amine captured CO2 will be directly electrolysed without CO2 desorption, compression, and purification, featuring extremely high efficiency and cost-effectiveness. Expected outcomes include the delivery of suitable amines, a family of chemically and s ....Direct Electrolysis of Amine Captured CO2 for Producing Syngas. This project aims to develop electrolysis of amine captured carbon dioxide (CO2) technology to integrate CO2 capture and syngas production powered by renewable electricity. The aqueous amine captured CO2 will be directly electrolysed without CO2 desorption, compression, and purification, featuring extremely high efficiency and cost-effectiveness. Expected outcomes include the delivery of suitable amines, a family of chemically and structurally controlled electrocatalysts, an in-depth understanding of CO2 electrolysis mechanisms, and the demonstration of robust electrolyser prototypes. This project will provide significant benefits to Australia’s energy and environmental security, and boost its clean energy industry and economic growth.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101396
Funder
Australian Research Council
Funding Amount
$360,218.00
Summary
Designing Single-atom catalysts for Renewable Waste Conversion to Urea. This DECRA aims to realise the direct electrochemical conversion of waste resources using renewable energy to generate urea at ambient conditions. By designing impurity-tolerant single atom catalysts and unearthing their structure-activity relationships, the utilisation of flue gas and wastewater will be materialised. This will advance our understanding in the field as current energy conversion reactions require pure feedsto ....Designing Single-atom catalysts for Renewable Waste Conversion to Urea. This DECRA aims to realise the direct electrochemical conversion of waste resources using renewable energy to generate urea at ambient conditions. By designing impurity-tolerant single atom catalysts and unearthing their structure-activity relationships, the utilisation of flue gas and wastewater will be materialised. This will advance our understanding in the field as current energy conversion reactions require pure feedstocks. Expected outcomes from the program is envisioned to lead to deployment of scalable decentralised modes of green urea production (substituting imports), and the knowledge transferrable to other areas of Australia’s emerging hydrogen economy, extending the scope of renewable Power-to-X to realise a circular economy.Read moreRead less
Energy dissipation characterisation in dynamic brittle fracture. Energy dissipation in dynamic fracture of brittle materials is pivotal in mining, civil engineering and defence. The project aims to develop a novel experimentally-validated multiscale theory, with associated models, for characterising and predicting the complete dynamic fracture process of brittle materials. This theory is expected to generate close-to-reality simulations critical for understanding fundamental aspects of energy di ....Energy dissipation characterisation in dynamic brittle fracture. Energy dissipation in dynamic fracture of brittle materials is pivotal in mining, civil engineering and defence. The project aims to develop a novel experimentally-validated multiscale theory, with associated models, for characterising and predicting the complete dynamic fracture process of brittle materials. This theory is expected to generate close-to-reality simulations critical for understanding fundamental aspects of energy dissipation in dynamic fracture. The outcomes will enable an optimised control of the fragment size in block cave mining and mineral processing, forecast and prevent fatal rock bursts in underground mines, and minimise catastrophic failures in critical infrastructures challenged by extreme loading, e.g. explosions.Read moreRead less
Advanced Gas Diffusion Electrodes For Electrochemical Manufacturing. This project aims to develop electrochemical conversion technologies to convert carbon dioxide into globally needed chemicals. It targets the bottleneck issues in managing the gas-liquid-solid reaction sites and improving the conversion efficiency of reactor, through the synthesis of advanced electrode materials, understanding of mass transfer and the engineering design of an electrochemical reactor. The expected outcomes will ....Advanced Gas Diffusion Electrodes For Electrochemical Manufacturing. This project aims to develop electrochemical conversion technologies to convert carbon dioxide into globally needed chemicals. It targets the bottleneck issues in managing the gas-liquid-solid reaction sites and improving the conversion efficiency of reactor, through the synthesis of advanced electrode materials, understanding of mass transfer and the engineering design of an electrochemical reactor. The expected outcomes will promote carbon neutral goals, bridge the renewable energy storage and sustainable chemical manufacturing gap, thus addressing key challenges faced by Australia and the world.Read moreRead less
Modelling, Design and Development of a Novel Wave-Energy Converter. Australia has an abundant source of wave-energy commercially untapped due to technical limitations of current wave-energy devices. This project aims to develop a novel wave-energy converter (WEC) that integrates energy capture and electricity generation through a single mechanism. This novel WEC can overcome or significantly reduce the drawbacks of existing WECs, is compact and light-weight (about 30 times less), ensures surviva ....Modelling, Design and Development of a Novel Wave-Energy Converter. Australia has an abundant source of wave-energy commercially untapped due to technical limitations of current wave-energy devices. This project aims to develop a novel wave-energy converter (WEC) that integrates energy capture and electricity generation through a single mechanism. This novel WEC can overcome or significantly reduce the drawbacks of existing WECs, is compact and light-weight (about 30 times less), ensures survivability, and has low-cost installation and maintenance. The project expects to deliver novel theoretical results in fluid-structure interaction, control systems and electrical conversion for WECs and other applications. The WEC will be demonstrated via a tested proof-of-concept physical model.Read moreRead less