Periconceptual Foundations For A Healthy Start To Life.
Funder
National Health and Medical Research Council
Funding Amount
$11,022,802.00
Summary
Preconception and early pregnancy is a critical time for a women's health and that of her future child. New research suggests that a woman's genetic potential, her lifestyle and the physical and socioeconomic environment in which she lives, and her biological and social relationship with her male partner, all impact on the long term health of her baby. Abnormal events around the time of conception and in early pregnancy can predispose a newborn to later occurrence, in adult life, of conditions i ....Preconception and early pregnancy is a critical time for a women's health and that of her future child. New research suggests that a woman's genetic potential, her lifestyle and the physical and socioeconomic environment in which she lives, and her biological and social relationship with her male partner, all impact on the long term health of her baby. Abnormal events around the time of conception and in early pregnancy can predispose a newborn to later occurrence, in adult life, of conditions including heart disease, diabetes, obesity and stroke. These adverse events originate in the way that eggs and sperm develop, the uterus is prepared for implantation, the attachment of the early embryo to the lining of the uterus and subsequent growth of the placenta. This Program will study the early life events that promote or limit development of a baby's true potential for successful and healthy life. A better understanding of how lifestyle and environment interact with genes and biology to facilitate optimal growth of the fetus will underpin new preventative measures and therapeutic treatments for infertility, miscarriage and other reproductive disorders. The knowledge gained will inform health policy and clinical practise to improve reproductive health in all Australian women and promote healthy development in all Australian children. The team of researchers is a world-class group of clinicians, scientists and epidemiologists who have made major contributions to our understanding of this area. This team will interface with clinics and hospitals that engage with women prior to and during pregnancy, while having the influence to alter clinical and health practices as well as public health policies. The team will utilize the latest, most technologically advanced laboratory methods and clinical skills, including gene profiling, imaging of early pregnancy, randomised clinical trials and access to the best epidemiological and statistical assessments.Read moreRead less
MICROSCALE PLANKTON AND PARTICLE DYNAMICS: COMPARING AND CONTRASTING AUSTRALIAN AND INTERNATIONAL SEAS. Microscopic phytoplankton are the basis of ocean ecosystems, but most predictions and measurements focus on processes that occur over kilometres. Our recent work shows that definite and regular submetre seascape topography exists. This grant will test the extent to which this seascape topography is the fundamental organisational unit of marine ecosystems and the extent to which it characteris ....MICROSCALE PLANKTON AND PARTICLE DYNAMICS: COMPARING AND CONTRASTING AUSTRALIAN AND INTERNATIONAL SEAS. Microscopic phytoplankton are the basis of ocean ecosystems, but most predictions and measurements focus on processes that occur over kilometres. Our recent work shows that definite and regular submetre seascape topography exists. This grant will test the extent to which this seascape topography is the fundamental organisational unit of marine ecosystems and the extent to which it characterises Australian coastal waters and open ocean water masses. This research takes a leadership role in defining and advancing our understanding of how marine ecosystems function. The project will bring over $200 million of Japanese infrastructure to Australia for 3 years.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100633
Funder
Australian Research Council
Funding Amount
$460,573.00
Summary
Microplastics accumulation in Australian coastal wetlands. This project aims to quantify the intensity, rate and impact of the accumulation of microplastic particles in Australia’s coastal wetlands for the first time. This multidisciplinary project will examine interactions between microplastics, wetland ecology and carbon dynamics using advanced analytical chemistry, biogeochemistry and environmental microbiology. Expected outcomes of this project include the world’s first nationwide analysis o ....Microplastics accumulation in Australian coastal wetlands. This project aims to quantify the intensity, rate and impact of the accumulation of microplastic particles in Australia’s coastal wetlands for the first time. This multidisciplinary project will examine interactions between microplastics, wetland ecology and carbon dynamics using advanced analytical chemistry, biogeochemistry and environmental microbiology. Expected outcomes of this project include the world’s first nationwide analysis of the sequestration of microplastics and their influence on the carbon cycle in coastal ecosystems. This work will provide significant benefits, such as facilitating decision-making about microplastics emissions reduction and coastal wetlands conservation.Read moreRead less
Special Research Initiatives - Grant ID: SR0354804
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impac ....ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impacts of contaminated soil and wastes, and land remediation. By facilitating communication, the network enhances national and international research coordination, interaction with regulators, end-users, industry, and other stakeholders, achievement of critical mass for new initiatives, enhances research training and contributes to a critical National Priority.Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
Heavy metal phytotoxicity in long-term contaminated soils: Implications for the development of Australian regulatory guidelines and realistic environmental risk assessment. Heavy metal contamination is a serious global environmental problem. There are >80,000 potentially contaminated sites in Australia alone with many of these sites in the urban environment and former mining areas. The current guidelines for phytotoxicity testing (National Environmental Protection Measure 1999) are based on tota ....Heavy metal phytotoxicity in long-term contaminated soils: Implications for the development of Australian regulatory guidelines and realistic environmental risk assessment. Heavy metal contamination is a serious global environmental problem. There are >80,000 potentially contaminated sites in Australia alone with many of these sites in the urban environment and former mining areas. The current guidelines for phytotoxicity testing (National Environmental Protection Measure 1999) are based on total metal concentrations that do not take into consideration of bioavailability and wide ranging Australian soil types. Serious concerns have been raised on the applicability of these guidelines and their protective limits in ecological risk assessment. This project aims at developing phytotoxicity guidelines applicable to a wide range of soil types common to Australia.Read moreRead less
The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecologic ....The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecological impacts of industry development. Important benefits of the project include information and tools for streamlining development approvals and accurately assessing risks to threatened species to improve outcomes for both our economy and our natural environment.Read moreRead less
The Role of the Single-Cell Environment in Microbial Invasion. This project aims to use a single-cell approach to develop a quantitative analysis of single-cell interactions to advance our understanding of complex bacterial behaviour fundamental to ecology, industry, technology and disease. Bacteria are ubiquitous on Earth and play key roles in nutrient cycles, biogeochemistry, pathogenesis, symbiosis and bioremediation among other processes. They exhibit complex behaviour and continuously invad ....The Role of the Single-Cell Environment in Microbial Invasion. This project aims to use a single-cell approach to develop a quantitative analysis of single-cell interactions to advance our understanding of complex bacterial behaviour fundamental to ecology, industry, technology and disease. Bacteria are ubiquitous on Earth and play key roles in nutrient cycles, biogeochemistry, pathogenesis, symbiosis and bioremediation among other processes. They exhibit complex behaviour and continuously invade animals, plants and new habitats. These behaviours are poorly understood in natural communities.Read moreRead less
Surplus baitfish? The consumption and bioenergetics of a predatory fish. This project aims to improve fisheries management of economically important baitfish by increasing our understanding of the ecosystem demand of predatory fish. The ecosystem demand of predatory fish is currently not understood, because it fails to include the considerable impact of juvenile fish, especially when they reside in an estuary. The project intends to implant acoustic transmitters, calibrated in a flume, to discov ....Surplus baitfish? The consumption and bioenergetics of a predatory fish. This project aims to improve fisheries management of economically important baitfish by increasing our understanding of the ecosystem demand of predatory fish. The ecosystem demand of predatory fish is currently not understood, because it fails to include the considerable impact of juvenile fish, especially when they reside in an estuary. The project intends to implant acoustic transmitters, calibrated in a flume, to discover bioenergetic rates in the field by determining the diet and the size- and temperature-dependent growth and biogenetics of a predatory fish species, from juvenile to adult, from estuary to the open sea. The outcomes include an ecosystem synthesis of related pelagic fish predators from catchment to coast.Read moreRead less
Environmental Genomics: Mining, climate change, water, crime and health. The new Environmental Genomics approach will employ high-powered genome sequencing systems to perform some of the first detailed genetic studies of Australian environments. The resulting high-resolution data will comprise a genetic audit, providing essential information for the accurate measurement of climate and environmental change. This method will dramatically improve the speed, and power of environmental impact assessm ....Environmental Genomics: Mining, climate change, water, crime and health. The new Environmental Genomics approach will employ high-powered genome sequencing systems to perform some of the first detailed genetic studies of Australian environments. The resulting high-resolution data will comprise a genetic audit, providing essential information for the accurate measurement of climate and environmental change. This method will dramatically improve the speed, and power of environmental impact assessments, permitting responsible resource development with major benefits to industry and the economy. It will also create new tools to improve water management and quality, biosecurity, forensics/policing and human health, as reflected by the diverse range of industry partners supporting this project.Read moreRead less