The dynamics of organic matter turnover in soils to improve the productivity of Australia's agricultural industries. Two recent national reports on the soils issues facing Australian agriculture (Reeves et al, 1997; CSIRO, 2000) concluded that soil structural degradation remains, after salinisation, our major threat to the sustainability of agricultural production. This research will provide fundamental understanding of how the dynamics of organic matter turnover benefit aggregate formation and ....The dynamics of organic matter turnover in soils to improve the productivity of Australia's agricultural industries. Two recent national reports on the soils issues facing Australian agriculture (Reeves et al, 1997; CSIRO, 2000) concluded that soil structural degradation remains, after salinisation, our major threat to the sustainability of agricultural production. This research will provide fundamental understanding of how the dynamics of organic matter turnover benefit aggregate formation and stability. This will advance the understanding of organic matter from simply considering the quantity of carbon present, to one of predicting the short- and long-term benefits to soil structure. This approach is innovative in the study of soil health, and has the potential to greatly advance the development of conservation farming systems.Read moreRead less
Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Combating subsoil acidity for sustainable production through managing plant cation-anion uptake. At least 50 million hectares of topsoil and 23 million ha of subsoil of Australian land are presently affected by acidity, with this area expanding due to the ongoing processes of acidification. Surface liming is ineffective in neutralizing subsoil acidity. The project will develop an innovative method that stimulates root proliferation and ameliorates subsoil acidity through manipulating the balance ....Combating subsoil acidity for sustainable production through managing plant cation-anion uptake. At least 50 million hectares of topsoil and 23 million ha of subsoil of Australian land are presently affected by acidity, with this area expanding due to the ongoing processes of acidification. Surface liming is ineffective in neutralizing subsoil acidity. The project will develop an innovative method that stimulates root proliferation and ameliorates subsoil acidity through manipulating the balance of nutrient uptake by plants. The effects of the developed method on nutrient use efficiency and leaching loss, and crop yields will be quantified under different soil types and climatic conditions.Read moreRead less
Understanding the control of male germ-line development by the germline-restrictive silencing factor in plants. The world population is currently increasing at an unprecedented rate, with a concomitant requirement to double the food production from the same amount of arable land. To ensure global political and social stability, equitably increasing sustainable food production without compromising environmental integrity remains a major challenge. This proposal investigates the molecular mechanis ....Understanding the control of male germ-line development by the germline-restrictive silencing factor in plants. The world population is currently increasing at an unprecedented rate, with a concomitant requirement to double the food production from the same amount of arable land. To ensure global political and social stability, equitably increasing sustainable food production without compromising environmental integrity remains a major challenge. This proposal investigates the molecular mechanisms underlying male germ line initiation and development in plants. Switching off male gamete development in some crop plants will create male sterile lines, which, when crossed with genetically distinct lines, will have the potential to produce hybrids that yield 20-30 percent more crop without additional inputs. Read moreRead less
Epigenetic programming of plant sperm cells. Most of the grains and seeds that form the world's food supply are the result of the successful functioning of sperm and egg cells during fertilisation. This proposal aims to investigate the nature of sperm cell genome programming in plants and unravel molecular processes that give these cells their unique identity. This innovative and challenging research will also provide an excellent opportunity for training the next generation of scientists. The o ....Epigenetic programming of plant sperm cells. Most of the grains and seeds that form the world's food supply are the result of the successful functioning of sperm and egg cells during fertilisation. This proposal aims to investigate the nature of sperm cell genome programming in plants and unravel molecular processes that give these cells their unique identity. This innovative and challenging research will also provide an excellent opportunity for training the next generation of scientists. The outcomes of this proposal will enhance Australia's international lead in this field and will pave the way toward the development of new approaches for sustaining and enhancing crop productivity under changing environmental conditions. Read moreRead less
Protecting the Australian chickpea industry through knowledge of the current Ascochyta rabiei fungal population and risk to resistance breeding strategies. Australian chickpea is highly vulnerable to epidemics of Ascochyta blight, which may cause total crop failure. This project will help to maintain Australia's position as a major global chickpea producer through maximising the life span of current resistance genes to A. rabiei. and determining the applicability of other potential resistance so ....Protecting the Australian chickpea industry through knowledge of the current Ascochyta rabiei fungal population and risk to resistance breeding strategies. Australian chickpea is highly vulnerable to epidemics of Ascochyta blight, which may cause total crop failure. This project will help to maintain Australia's position as a major global chickpea producer through maximising the life span of current resistance genes to A. rabiei. and determining the applicability of other potential resistance sources. The knowledge that will be generated regarding the pathogen's potential to overcome host resistance is imperative for developing future disease management strategies, especially since more aggressive isolates exist outside Australia. The project findings will feed directly into the National Australian Chickpea Breeding Program.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668294
Funder
Australian Research Council
Funding Amount
$110,000.00
Summary
Isotope Ratio Mass Spectrometry Facility for Nitrogen and Water Analysis in Plants. Continual improvement to agricultural plant production is key to maintaining future sustainable growth in Australian agriculture. Our respective research teams are focussed on improving how plants utilise both nitrogen and water. Many questions remain with respect to where, how and when plants use and or access these important nutrients. The proposed facility will enable plant scientists to begin in-depth anal ....Isotope Ratio Mass Spectrometry Facility for Nitrogen and Water Analysis in Plants. Continual improvement to agricultural plant production is key to maintaining future sustainable growth in Australian agriculture. Our respective research teams are focussed on improving how plants utilise both nitrogen and water. Many questions remain with respect to where, how and when plants use and or access these important nutrients. The proposed facility will enable plant scientists to begin in-depth analysis of both nitrogen transport mechanisms and the ability to model root development and water allocation in crop species. This research will ultimately lead to improved knowledge on how plants respond to their environment and where modifications can be made to generate sustainable crops suited to Australian agriculture.Read moreRead less
Managing subsoil constraints for increased productivity and water use efficiency. Subsoil constraints limit crop production in up to 60% of agricultural land. This project examines the impacts of organic matter incoporation, deep placement of nutrients, use of primer crops, calcium addition and their combination on amelioration of subsoil constraints and thereby on the improvement of root growth, water use and crop yield in high-rainfall region. The best-bet management strategy will be developed ....Managing subsoil constraints for increased productivity and water use efficiency. Subsoil constraints limit crop production in up to 60% of agricultural land. This project examines the impacts of organic matter incoporation, deep placement of nutrients, use of primer crops, calcium addition and their combination on amelioration of subsoil constraints and thereby on the improvement of root growth, water use and crop yield in high-rainfall region. The best-bet management strategy will be developed.Read moreRead less
ASPREE-D; Aspirin In The Prevention Of Depression In The Elderly
Funder
National Health and Medical Research Council
Funding Amount
$796,784.00
Summary
The ASPREE (ASPirin in Reducing Events in the Elderly) study is a 5 year RCT of aspirin (100mg daily) or placebo in 19,000 healthy people over 70. We aim to augment the existing infrastructure of ASPREE in order to confirm the utility of aspirin for the prevention of depression in the elderly (ASPREE-D). The primary aim of ASPREE-D is to determine if use of low-dose aspirin reduces the incidence of de-novo episodes of depression in healthy individuals over 70 years of age.