Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the im ....Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the impact of their structure on biological properties. The benefits of this project will include new fundamental insights into improving nanoparticle design for vaccine delivery, as well as the expansion of Australia’s knowledge base in the area of biodegradable polymers.Read moreRead less
Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and technique ....Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and techniques in the fields of reactive polymer synthesis, functional membrane fabrication and application in bioseparation. The innovative membranes developed in the project are able to improve the production capacity of therapeutic protein manufacturing processes, providing significant economic benefits to Australia.Read moreRead less
Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective mole ....Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective molecule transport. The membranes developed in the project have great potentials for improving the production capacity and sustainability of Australian industries, e.g., pharmaceutical manufacturing, bioethanol production and petroleum refining, providing significant economic and environmental benefits to Australia.Read moreRead less
Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include ne ....Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include new membrane compositions, design principles, fabrication techniques, and proof-of-concept production of scalable, high-performance composite membranes. This project should produce significant economic and environmental benefits in the development of advanced membranes, pharmaceuticals, and agrochemicals.Read moreRead less
Extremely lightweight and superelastic cellular materials. This project aims to synthesise a new generation of extremely lightweight, superelastic yet mechanically robust graphene-based cellular materials, develop new strategies to strengthen and functionalise them with other functional polymers or nanoparticles, and explore new techniques to characterise their unique mechanical, electrical and thermal properties for a range of potential applications. The new knowledge obtained would significant ....Extremely lightweight and superelastic cellular materials. This project aims to synthesise a new generation of extremely lightweight, superelastic yet mechanically robust graphene-based cellular materials, develop new strategies to strengthen and functionalise them with other functional polymers or nanoparticles, and explore new techniques to characterise their unique mechanical, electrical and thermal properties for a range of potential applications. The new knowledge obtained would significantly advance our understanding of extremely lightweight and multifunctional cellular materials as well as graphene-based bulk materials. Project outcomes are expected to help generate high value-added technological applications from natural graphite.Read moreRead less
Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a so ....Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a solid foundation for realising qualified spintronics materials for spintronics devices. The expected outcomes are low power, high speed, spintronics devices, enhancing Australia’s strength in spintronics research.Read moreRead less
High value micron-sized particles from a novel antisolvent vapour spray drying system. Convective antisolvent precipitation is a novel route in producing particles from spray drying by adding an anti-solvent to the drying medium. This project will allow conventional spray dryers to produce more sophisticated ultrafine and encapsulated particles for use in food, pharmaceuticals and other high value applications.
Engineering the Microstructure of Electrodes for Advanced Fuel Cells. A polymer solution-based integration technique is proposed to be developed to fabricate polymer electrolyte membrane fuel cells, allowing for effective engineering of the porous networks and interfaces within electrodes and cells. This novel systems materials engineering approach is expected to overcome the drawbacks of the conventional hot pressing method, enabling precise integration of nanostructured electrodes and membrane ....Engineering the Microstructure of Electrodes for Advanced Fuel Cells. A polymer solution-based integration technique is proposed to be developed to fabricate polymer electrolyte membrane fuel cells, allowing for effective engineering of the porous networks and interfaces within electrodes and cells. This novel systems materials engineering approach is expected to overcome the drawbacks of the conventional hot pressing method, enabling precise integration of nanostructured electrodes and membrane into high-performance, flexible fuel cells. The outcomes of this research aim to provide a unique opportunity for Australia to become a world leader in the rapidly-emerging clean energy technology, and critical manufacturing of new energy generation systems for domestic uses and exports, thereby producing important economic benefits.Read moreRead less
Development of Novel Functionalised Two-dimensional Nanomaterials. This project aims to develop a series of novel 2D nanomaterials and their nanocomposites that have applications ranging from energy storage via a functional separator for batteries to thermal management devices. Developing novel functional 2D nanomaterials is important for several applications including energy storage, composite materials, and thermal management, as well as advancing knowledge in the control design of 2D nanomate ....Development of Novel Functionalised Two-dimensional Nanomaterials. This project aims to develop a series of novel 2D nanomaterials and their nanocomposites that have applications ranging from energy storage via a functional separator for batteries to thermal management devices. Developing novel functional 2D nanomaterials is important for several applications including energy storage, composite materials, and thermal management, as well as advancing knowledge in the control design of 2D nanomaterials and to promote the development of sustainable energy storage and thermal management technologies. The benefits to Australia, will be in addressing energy and environmental concerns by developing new clean and environmentally friendly energy devices and boosting national economic growth.Read moreRead less
Two-dimensional transition metal nitrides for energy applications. This project aims to develop novel nanomaterials for sustainable energy applications such as blue energy generation and energy storage. The focus is to explore novel 2D transition metal nitride nanomaterials and their advanced heterostructures with large specific surface area, high electrical conductivity and chemical stability. The expected outcomes include development of high-performance devices such as osmotic energy harvestin ....Two-dimensional transition metal nitrides for energy applications. This project aims to develop novel nanomaterials for sustainable energy applications such as blue energy generation and energy storage. The focus is to explore novel 2D transition metal nitride nanomaterials and their advanced heterostructures with large specific surface area, high electrical conductivity and chemical stability. The expected outcomes include development of high-performance devices such as osmotic energy harvesting devices for blue energy generation and micro-supercapacitors for energy storage. This should promote the growth of sectors in advanced materials, sustainable energy generation, smart energy storage and manufacturing, bringing efficient energy generation and storage system benefits to the Australia and the world.Read moreRead less