New dielectric materials: Improving storage density of high temperature multilayer ceramic capacitors to sustainably meet future energy demands. Electrical energy generation from renewable sources, such as solar, wind and geothermal, provide enormous potential for meeting future energy demands. However, the ability to store and control this energy for miniaturisation and modularisation in applications requiring a wide temperature usage range is a limiting factor that needs to be addressed. This ....New dielectric materials: Improving storage density of high temperature multilayer ceramic capacitors to sustainably meet future energy demands. Electrical energy generation from renewable sources, such as solar, wind and geothermal, provide enormous potential for meeting future energy demands. However, the ability to store and control this energy for miniaturisation and modularisation in applications requiring a wide temperature usage range is a limiting factor that needs to be addressed. This project aims to develop new bismuth-based lead-free dielectric materials for improving the storage density of high temperature multilayer ceramic capacitors for sustainable applications in the energy and vehicle industries, where high temperature stability and high volumetric efficiency are crucial.Read moreRead less
Understanding phenotypes: contributions from studying mutations in a model organism. The distribution of fish across aquatic habitats will be determined jointly by the swimming speed and endurance requirements imposed by features of the environment, such as water flow, and by the swimming capacity of the fish. This project will use zebrafish to characterise how body shape and physiology interact to determine swimming capacity.
A new statistical framework to understand the biological basis of Ankylosing Spondylitis and other complex diseases. Ankylosing Spondylitis (AS) is a highly heritable and common inflammatory arthritis which causes stiffness and progressive fusion of the spine, decreased quality of life and reduced lifespan. There is no known cure for the condition. This project aims to identify genes and biological pathways involved in AS pathogenesis using a new statistical framework that will be applied to tho ....A new statistical framework to understand the biological basis of Ankylosing Spondylitis and other complex diseases. Ankylosing Spondylitis (AS) is a highly heritable and common inflammatory arthritis which causes stiffness and progressive fusion of the spine, decreased quality of life and reduced lifespan. There is no known cure for the condition. This project aims to identify genes and biological pathways involved in AS pathogenesis using a new statistical framework that will be applied to thousands of individuals with the disease. This project will improve understanding of the underlying mechanisms involved in AS pathophysiology, inform development of new drug treatments for the condition, and create a powerful new statistical approach that can be used to identify biological pathways which are important in the pathogenesis of other complex diseases.Read moreRead less
Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and l ....Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and lift productivity by managing innovation for Australia’s industries.Read moreRead less
Developing methods for the analysis of massively parallel sequencing data in family studies. This project will develop analytical methods to use the latest, high-throughput method of generating sequencing data, i.e. the letters of the human genome alphabet. These tools will be used to identify the causal mutations in families with inherited disorders, leading to diagnostic tests for these families.
Elucidating the genetics of attention deficit hyperactivity disorder by integrating pathway and prediction analyses. Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in children; while treatments are available they are ineffective for many patients. This project will develop methods for predicting genetic effects at the level of the biological mechanism to assist in identifying new drug targets and behavioural interventions.
Operator algebras as models for dynamics and geometry. Operator algebra is the mathematical theory which describes quantum physics and predicts how quantum systems will behave. Through this project, the researcher's recent discoveries in operator algebra will give us new insight into the dynamics and geometry - that is, the behaviour and shape - of the quantum world.
Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a so ....Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a solid foundation for realising qualified spintronics materials for spintronics devices. The expected outcomes are low power, high speed, spintronics devices, enhancing Australia’s strength in spintronics research.Read moreRead less
Interface engineering of complex oxide heterostructures for high efficiency thermoelectric energy conversion. Thermoelectric materials offer an opportunity for economic recovery of the waste heat from exhaust gases to reduce operational costs and greenhouse emissions. Success of this program will facilitate the development of thermoelectric materials with high energy conversion efficiency for viable applications.
Understanding the molecular mechanisms of intellectual disability. Intellectual disability is frequent in the population, with one in every fifty people in the world directly affected. This project will improve our understanding of the correct development and function of the brain required for cognition by investigating specific roles and regulation of key molecules involved.