Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to ....Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to investigate a broad range of cognitive and communication functions. Benefits will include potential technologies and algorithms to assist listening (in devices such as hearing aids), language development and reading.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Deciphering The Role Of Atypical DNA Methylation In Neuronal Genome Regulation And Neurological Disorders
Funder
National Health and Medical Research Council
Funding Amount
$773,484.00
Summary
This research will use a combination of genomic, biochemical and functional genomics approaches to investigate the role of the atypical mCH form of DNA methylation in neuronal genome regulation and function, and provide new insights into the role of the epigenome in healthy brain function and neural pathologies.
Industrial Transformation Research Hubs - Grant ID: IH230100005
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for convert ....ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for converting gaseous waste from sectors that cannot easily avoid emission into useful chemicals, which in turn realize carbon neutrality and negativity. The outcomes of this Hub are likely to be transformative for industry, the economy, and society in new-type renewable energy resources through decreasing environmental pollutants. Read moreRead less
High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significa ....High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significant advances in energy efficient data storage devices, and commercialisation of the technology to Australian industries.Read moreRead less
Development Of Iron Complexes For The Treatment Of FriedreichÍs Ataxia & The Role Of Frataxin In Iron Metabolism
Funder
National Health and Medical Research Council
Funding Amount
$616,143.00
Summary
Friedreich's ataxia (FA) is a neuro- & cardio-degenerative disease where there is an accumulation of toxic iron (Fe) in the mitochondrion. Work from our current NHMRC grant showed iron plays a significant role in FA pathology In fact, the CIs dissected the mechanisms of mitochondrial iron-loading & have published 8 papers in high impact journals with 3 papers in PNAS USA in the last 2 yrs Understanding of this process has led to the design of rationalised drugs for FA This work in this Renewal c ....Friedreich's ataxia (FA) is a neuro- & cardio-degenerative disease where there is an accumulation of toxic iron (Fe) in the mitochondrion. Work from our current NHMRC grant showed iron plays a significant role in FA pathology In fact, the CIs dissected the mechanisms of mitochondrial iron-loading & have published 8 papers in high impact journals with 3 papers in PNAS USA in the last 2 yrs Understanding of this process has led to the design of rationalised drugs for FA This work in this Renewal could lead to novel therapies for FARead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100032
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research co ....Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research collaborations and a wide range of next-generation technologies including non-invasive medical instruments, wearable devices, communication, quantum information systems and energy storage solutions. This should enable local design and construction of hybrid devices and advance the growth of local high-technology industries.Read moreRead less
Does word similarity across languages help or hinder bilingual speakers? This project aims to understand in more detail how bilinguals can accurately speak in both their languages. Speaking is a complex skill, particularly if you have two languages to choose from, which will be true for over half of Australia’s population by 2025. This project aims to investigate the factors that influence speech production in both monolinguals and bilinguals including those with language impairment, and develop ....Does word similarity across languages help or hinder bilingual speakers? This project aims to understand in more detail how bilinguals can accurately speak in both their languages. Speaking is a complex skill, particularly if you have two languages to choose from, which will be true for over half of Australia’s population by 2025. This project aims to investigate the factors that influence speech production in both monolinguals and bilinguals including those with language impairment, and develop a better bilingual theory. The benefit of this new theory will be to provide a clear basis for diagnosis and treatment for children in bilingual households who have problems learning to speak, and for bilingual people with language problems after a stroke or dementia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100074
Funder
Australian Research Council
Funding Amount
$520,000.00
Summary
Facilities for automated high-throughput slide scanning and stereology. The equipment requested will facilitate the work of the Australian Mouse Brain Mapping Consortium, a consortium of Australian research groups collaborating to provide the only mouse model brain mapping capability in the country. The consortium brings together laboratory, neuroimaging and computational expertise in a comprehensive framework for imaging the mouse brain. This will help researchers to study mouse models of genet ....Facilities for automated high-throughput slide scanning and stereology. The equipment requested will facilitate the work of the Australian Mouse Brain Mapping Consortium, a consortium of Australian research groups collaborating to provide the only mouse model brain mapping capability in the country. The consortium brings together laboratory, neuroimaging and computational expertise in a comprehensive framework for imaging the mouse brain. This will help researchers to study mouse models of genetic and acquired disorders across the life-span. Remote viewing and analysis capabilities will help overcome the 'tyranny of distance', increasing national access to the facility. Repositories of digitised images will increase the availability of valuable research material to other Australian and international researchers.Read moreRead less