System-level characterisation of the siphonophore, Indo-Pacific man o' war. The Indo-Pacific man o' war (bluebottle), is a cnidarian from the siphonophore order. These animals frequent Australian beaches in swarms and cause thousands of stings every year. The project proposes to profile the genome, transcriptome, epigenome, and proteome of the bluebottle to gain insight into its life cycle, its behaviour, and toxins. Expected outcomes include the generation of novel information related to bluebo ....System-level characterisation of the siphonophore, Indo-Pacific man o' war. The Indo-Pacific man o' war (bluebottle), is a cnidarian from the siphonophore order. These animals frequent Australian beaches in swarms and cause thousands of stings every year. The project proposes to profile the genome, transcriptome, epigenome, and proteome of the bluebottle to gain insight into its life cycle, its behaviour, and toxins. Expected outcomes include the generation of novel information related to bluebottle gene regulation and its toxin repertoire, which will be highly beneficial for the design of future sting treatment strategies. Given that the bluebottle is a colony made of functionally specialised polyps, this study will also provide significant novel insight into the origins and evolution of animal multicellularity.Read moreRead less
Next generation high throughput lipidomics using adaptive modelling. This project aims to develop a unique high-throughput method to capture the lipidomic profile of human plasma suitable for large human population screening. Lipids are fundamental to every biological system, but our understanding of their regulation in humans have been largely superficial. By incorporating a new lipidomics approach, with genomic data, this project aims to expand our understanding of human biology by identifying ....Next generation high throughput lipidomics using adaptive modelling. This project aims to develop a unique high-throughput method to capture the lipidomic profile of human plasma suitable for large human population screening. Lipids are fundamental to every biological system, but our understanding of their regulation in humans have been largely superficial. By incorporating a new lipidomics approach, with genomic data, this project aims to expand our understanding of human biology by identifying regulators of lipid metabolism. The large diversity in humans necessitate sufficient sample sizes to identify true genetic regulators, but to date techniques capturing phenotypic data (lipids) have been largely limited. It is anticipated that this study will identify new regulators of lipid metabolism in humans.Read moreRead less
Understanding disease resistance gene evolution across the Brassicaceae. Pan genomes represent the diversity of a species, including structural and sequence variation, which cannot be provided by a reference genome alone. In this project we will characterise resistance gene diversity across the Brassicaceae pan genomes. Through comparison with resistance gene diversity in cultivated Brassica species we will understand selection underlying resistance gene evolution in wild species and subsequent ....Understanding disease resistance gene evolution across the Brassicaceae. Pan genomes represent the diversity of a species, including structural and sequence variation, which cannot be provided by a reference genome alone. In this project we will characterise resistance gene diversity across the Brassicaceae pan genomes. Through comparison with resistance gene diversity in cultivated Brassica species we will understand selection underlying resistance gene evolution in wild species and subsequent domestication and breeding. Knowledge on how variation affects disease susceptibility, especially to the devastating fungal pathogen blackleg, and contributes to phenotypic variation, will lead to improved plant protection strategies and increased crop resilience.Read moreRead less
Inorganic/organic Hybrids for flexible thermoelectric generators. Flexible thermoelectric generators can directly harvest electricity from body heat, offering a new technology for wearable electronics, but their unsatisfied performance limits their applications. This project aims to design high-efficient and mechanically robust flexible thermoelectric devices based on novel hybrids with quantum dots and conducting polymers as key components. The key breakthrough is to establish unique devices wi ....Inorganic/organic Hybrids for flexible thermoelectric generators. Flexible thermoelectric generators can directly harvest electricity from body heat, offering a new technology for wearable electronics, but their unsatisfied performance limits their applications. This project aims to design high-efficient and mechanically robust flexible thermoelectric devices based on novel hybrids with quantum dots and conducting polymers as key components. The key breakthrough is to establish unique devices with record-high thermoelectric efficiency and to illustrate the underlying mechanisms for searching new-type flexible thermoelectrics. The expected outcomes will lead to innovative technology for energy conversion and advanced manufacturing and place Australia at the forefront of energy and manufacturing fields.Read moreRead less
Exploiting shear to form new structures of carbon. This project aims to create new, technologically-interesting, materials by combining shear (sliding forces) with high pressure. The work will use both modelling and experiments to understand the pathways to form new materials such as a different form of diamond that is predicted to be harder than regular diamond. Such a material could be used in coatings for cutting tools or ultra-low-scratch surfaces. Expected outcomes include both an understan ....Exploiting shear to form new structures of carbon. This project aims to create new, technologically-interesting, materials by combining shear (sliding forces) with high pressure. The work will use both modelling and experiments to understand the pathways to form new materials such as a different form of diamond that is predicted to be harder than regular diamond. Such a material could be used in coatings for cutting tools or ultra-low-scratch surfaces. Expected outcomes include both an understanding of the importance of shear in the study of high-pressure science, and as a tool to manufacture new functional materials.Read moreRead less
The adaptive evolution of key methane-utilising microorganisms. This project aims to characterise the evolutionary adaptations of a group of microorganisms with a key role in mitigating the release of methane into the atmosphere. Innovative molecular and visualisation-based approaches will be applied to uncover their metabolic diversity and evolutionary history. An important outcome of this study will be the comprehensive understanding of the contribution and impact these microorganisms have on ....The adaptive evolution of key methane-utilising microorganisms. This project aims to characterise the evolutionary adaptations of a group of microorganisms with a key role in mitigating the release of methane into the atmosphere. Innovative molecular and visualisation-based approaches will be applied to uncover their metabolic diversity and evolutionary history. An important outcome of this study will be the comprehensive understanding of the contribution and impact these microorganisms have on the global carbon cycle, which will importantly inform accurate climate change models. This has clear benefits for society, given the precision of such models is essential in our ability to minimise the impact and associated cost of global warming.Read moreRead less
Genomics to rust proof the humble oat. This project aims to reduce the impact of the damaging and currently intractable fungal pathogen crown rust (OCR) in Australian oat production. The expected project outcomes are: new sources of enduring high value resistance to OCR, tools to accelerate the use of these resistances, and locally adapted OCR resistant oat germplasm for use in developing profitable oat varieties. The project will use new approaches to tap very recently released genomic resource ....Genomics to rust proof the humble oat. This project aims to reduce the impact of the damaging and currently intractable fungal pathogen crown rust (OCR) in Australian oat production. The expected project outcomes are: new sources of enduring high value resistance to OCR, tools to accelerate the use of these resistances, and locally adapted OCR resistant oat germplasm for use in developing profitable oat varieties. The project will use new approaches to tap very recently released genomic resources and unique oat/ OCR resources assembled over many years. It will lead to responsible stewardship of broadly effective OCR resistance in grazing/milling/hay oats, increasing grower profitability, reducing reliance on fungicides, and underpinning planned growth in our export oat market. Read moreRead less
Wearable thermoelectrics for personal heat management. Thermoregulation has substantial implications for energy consumption and human comfort and health. This project aims to develop wearable thermoelectric materials and devices with high cooling performance for personal heat management. A novel assembly approach, coupled with device design and materials engineering strategies, will be developed to engineer flexible thermoelectric materials with unique structures and chemistry. The key breakthro ....Wearable thermoelectrics for personal heat management. Thermoregulation has substantial implications for energy consumption and human comfort and health. This project aims to develop wearable thermoelectric materials and devices with high cooling performance for personal heat management. A novel assembly approach, coupled with device design and materials engineering strategies, will be developed to engineer flexible thermoelectric materials with unique structures and chemistry. The key breakthrough is to design wearable thermoelectric devices with high flexibility and user comfort. The expected outcomes of this project will lead to an innovative cooling technology for personal heat management, which will place Australia at the forefront of wearable electronics and garment industry.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH230100005
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for convert ....ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for converting gaseous waste from sectors that cannot easily avoid emission into useful chemicals, which in turn realize carbon neutrality and negativity. The outcomes of this Hub are likely to be transformative for industry, the economy, and society in new-type renewable energy resources through decreasing environmental pollutants. Read moreRead less
High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significa ....High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significant advances in energy efficient data storage devices, and commercialisation of the technology to Australian industries.Read moreRead less