Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drive ....Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drives low and high-level brain functions, i.e., creating a window into the mind. In the future, outcomes from this study could improve our understanding of mental disorders, advance computer brain interface technology, and inspire the next paradigm shift in artificial intelligence.Read moreRead less
Design of Functionalized Mesoporous Fullerenes for Clean Energy. This project aims to design multifunctional, noble metal-free, and highly ordered mesoporous fullerene with a high conductivity and different porous structures, functionalised with nitrogen and/or metal and metal oxide nanoparticles in both powder and film forms. The most promising, stable, and highly efficient noble metal-free electrode catalyst system will be designed with the functionalised mesoporous fullerenes for polymer elec ....Design of Functionalized Mesoporous Fullerenes for Clean Energy. This project aims to design multifunctional, noble metal-free, and highly ordered mesoporous fullerene with a high conductivity and different porous structures, functionalised with nitrogen and/or metal and metal oxide nanoparticles in both powder and film forms. The most promising, stable, and highly efficient noble metal-free electrode catalyst system will be designed with the functionalised mesoporous fullerenes for polymer electrolyte membrane and direct methanol fuel cells. This novel highly efficient and low cost electrode system for fuel cells aims to help address clean energy generation and environmental problems and create new opportunities for Australian industries.Read moreRead less
Comparing properties of innate immune proteins of bats and humans. Supra-molecular protein complexes known as signalosomes drive our innate immune response by forming large signaling hubs capable of recruiting downstream effectors. This project aims to compare the properties and structure of human and bat signalosomes and discover the molecular origins of the “supra-immunity” of bats. In this context, the project expects to generate new knowledge concerning the fundamental molecular mechanisms t ....Comparing properties of innate immune proteins of bats and humans. Supra-molecular protein complexes known as signalosomes drive our innate immune response by forming large signaling hubs capable of recruiting downstream effectors. This project aims to compare the properties and structure of human and bat signalosomes and discover the molecular origins of the “supra-immunity” of bats. In this context, the project expects to generate new knowledge concerning the fundamental molecular mechanisms that regulate the signalosomes. The intended outcome is to answer the long-standing question of control of speed and amplitude of innate immune response at the molecular level. Both locally and internationally, this new approach should provide benefits across structural biology, molecular evolution and biotechnology.Read moreRead less
Brain structure and function of neonates at risk for stuttering. The aim of the project is to determine whether the brain abnormalities that have been found in people who stutter are present at birth. The hypothesis is that the brains of neonates who subsequently start to stutter will differ significantly from those who do not. This is the first project to investigate the brains of infants before they start to stutter.
Multifunctional 2D materials for sustainable energy applications. This project seeks to explore the great potential of novel graphene-like two dimensional (2-D) materials for energy applications. 2-D materials, which possess atomic or molecular thickness and infinite planar lengths, are regarded as a building block for many applications due to their unique nanostructures, electronic and mechanical properties. This project is focused on the design and exploration of layered two-dimensional artifi ....Multifunctional 2D materials for sustainable energy applications. This project seeks to explore the great potential of novel graphene-like two dimensional (2-D) materials for energy applications. 2-D materials, which possess atomic or molecular thickness and infinite planar lengths, are regarded as a building block for many applications due to their unique nanostructures, electronic and mechanical properties. This project is focused on the design and exploration of layered two-dimensional artificial graphene and graphene analogues with ‘on-demand’ properties to exploit advanced energy applications. There is now a pressing need to integrate graphene sheets into multidimensional and multifunctional systems with spatially well-defined configurations, and integrated systems with a controllable structure and predictable performance. Project outcomes may lead to next-generation devices in energy storage and other applications.Read moreRead less
Every Day Matters: Reducing School Non-Attendance in Autistic Students. Autistic children miss one day a week of school, three times more than their peers. This significantly impacts their learning, wellbeing and later, their vocational outcomes. This project aims to identify the factors that put autistic children at increased risk of missing school and map the supports and interventions used to reduce school non-attendance. Expected outcomes include an autism-specific model of the how and why s ....Every Day Matters: Reducing School Non-Attendance in Autistic Students. Autistic children miss one day a week of school, three times more than their peers. This significantly impacts their learning, wellbeing and later, their vocational outcomes. This project aims to identify the factors that put autistic children at increased risk of missing school and map the supports and interventions used to reduce school non-attendance. Expected outcomes include an autism-specific model of the how and why school non-attendance is elevated for autistic students. It is anticipated that this model make the important step of enabling teachers and professionals to identify which autistic children are most at risk of absenteeism and select the best strategies to support a positive and beneficial return to school.Read moreRead less
Designing plasmon-enhanced photocatalysts for solar-driven water pollutant removal. The outcomes of this program will lead to a new class of composite photocatalysts for efficient water purification using sunlight. Such technology will speed up the transition of Australian environmental and energy industries from a fossil fuel economy to renewable energy economy.
New generation nanostructured coatings with combined control of spectral and angular emissivity. The aim of this project is to generate a complete scientific understanding of a new generation of hybrid, tri-layered, optically-selective coatings. The new design paradigm combines the very different attributes of smooth and nanostructured layers so that superior and simultaneous control of both spectral and angular properties of light can be achieved. Existing theory will be extended so that quanti ....New generation nanostructured coatings with combined control of spectral and angular emissivity. The aim of this project is to generate a complete scientific understanding of a new generation of hybrid, tri-layered, optically-selective coatings. The new design paradigm combines the very different attributes of smooth and nanostructured layers so that superior and simultaneous control of both spectral and angular properties of light can be achieved. Existing theory will be extended so that quantitative analyses of these new systems and other hybrids become possible and new and improved fabrication techniques will be developed. The work will unlock new technological possibilities for coating performance and application and is likely to be associated with significant improvements in energy conservation and generation. Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
Exploring electronic functionality in low-dimensional carbon and boron-nitride nanomaterials via advanced theoretical modelling. This project will spawn innovative carbon/boron nitride materials for next-generation electronics devices by devising new strategies to manipulate and control electronic structure as well as charge/spin transport properties. Outcomes will include technological breakthroughs leading to truly smaller, faster and smarter electronics materials.