Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
New carbon phases synthesized under extreme conditions. This project aims to address one of the major fundamental puzzles in carbon science; how to experimentally synthesize new phases of carbon predicted by theory. This could be approached via a combination of high pressure and high-energy ion irradiation to transform novel nano-carbon precursors. The expected outcomes include new phases of carbon with unexplored properties, an understanding of the pathways for synthesis of carbon materials, an ....New carbon phases synthesized under extreme conditions. This project aims to address one of the major fundamental puzzles in carbon science; how to experimentally synthesize new phases of carbon predicted by theory. This could be approached via a combination of high pressure and high-energy ion irradiation to transform novel nano-carbon precursors. The expected outcomes include new phases of carbon with unexplored properties, an understanding of the pathways for synthesis of carbon materials, and new computational tools to understand nano-carbon materials under extreme conditions. This should provide benefits for industries seeking advanced materials for modern manufacturing.Read moreRead less