A Centre For Research Excellence In Cerebral Palsy (CRE-CP)
Funder
National Health and Medical Research Council
Funding Amount
$2,622,042.00
Summary
Cerebral palsy is the most common physical disability in childhood. Our objective is to bring about a radical improvement in the treatment of individuals with cerebral palsy, both children and adults, and to determine better ways to assist their families. Emphasis will be placed on early detection of health issues and rigorous evaluation of management options. We will train more researchers and ensure that all the knowledge generated is made available to families and health care professionals.
Genome-wide Association Study (GWAS) For Juvenile-onset Myopia And Its Component Measures To Identify Molecular Pathways To Prevent Myopia
Funder
National Health and Medical Research Council
Funding Amount
$495,364.00
Summary
We will examine 2,000 young adults from the Western Australian Raine Cohort at the Lions Eye Institute / University of Western Australia. Ocular data will be collected relating to myopia (short-sightedness) and will be combined with extensive previous childhood and genetic research data collected on the Cohort, to investigate the genetic and environmental factors predisposing to myopia. This will assist in understanding the factors leading to myopia.
A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic ev ....A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic evaluation, improving the quality of life and wellbeing of older Australians, and will assist in determining the relative cost effectiveness of new and existing services.
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Identifying Resistance Mechanisms Of Targeted BRAF Inhibitors In Metastatic Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$379,015.00
Summary
Late-stage melanoma is an aggressive skin cancer for which traditional treatment strategies such as chemotherapy are ineffective. Recently, a new class of targeted drugs (BRAF inhibitors) has become the standard of care for a subset of melanoma patients; however, long term treatment success is complicated by drug resistance. This study will identify the causes of resistance with the purpose to improve targeted drug strategies and increase survival rates for late-stage melanoma patients.
Harnessing Information Technology To Improve Self-management Behaviours And Health Outcome In People With Heart Failure: A Smarthome Ecosystem Living Lab Study
Funder
National Health and Medical Research Council
Funding Amount
$1,120,226.00
Summary
The burden of heart failure in Australia is substantial. Management of heart failure is complex and requires self-management of symptoms and behaviour change, which requires ongoing education and support to achieve. Current approaches for supporting self-management do not meet the needs of people with heart failure or the healthcare system. This Australian first project aims to co-design an intelligent smart home ecosystem (Smart Heart) to support the management for people with heart failure.
Improving Access To Psychological Services For People With Cancer: A Randomised Control Trial Of An Interactive Web-Based Intervention
Funder
National Health and Medical Research Council
Funding Amount
$612,715.00
Summary
Approximately 35% of people diagnosed with cancer will experience persistent significant distress, and unmet psychological supportive care needs in Australian cancer patients are highly prevalent. The web presents a unique method of delivery of supportive care. However, to our knowledge this type of intervention has not been examined. This two-phased study will develop and test a novel web-based intervention to improve psychological outcomes in cancer patients experiencing distress.
Thermoelectric devices for high-performing localised coolers. This project aims to develop a lightweight, low-energy-consumption, and high-durability wearable thermoelectric cooler for localised cooling using a novel industry-led approach, coupled with device design and materials engineering strategies. The key breakthrough expected is to design wearable thermoelectric coolers by using flexible substrates and thermoelectric materials with engineered chemistry and unique structures for achieving ....Thermoelectric devices for high-performing localised coolers. This project aims to develop a lightweight, low-energy-consumption, and high-durability wearable thermoelectric cooler for localised cooling using a novel industry-led approach, coupled with device design and materials engineering strategies. The key breakthrough expected is to design wearable thermoelectric coolers by using flexible substrates and thermoelectric materials with engineered chemistry and unique structures for achieving localised, instant, and controllable cooling with super low power input for personal usage in building and mining industry. Expected outcomes include innovative technologies for achieving high-efficiency cooling, which will provide significant economic and commercial benefits for Australia.Read moreRead less
New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve ....New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve battery performance at a lower price and make a substantial impact to the energy supply technologies and industries in Australia and benefit the environment in the long run.Read moreRead less