Fracture Associated Premature Mortality; An International Consortium
Funder
National Health and Medical Research Council
Funding Amount
$579,807.00
Summary
Following an osteoporotic fracture there is an increased premature mortality compared with someone who has not fractured. There is also evidence that anti-osteoporosis medication reduces this premature mortality. This study will determine the size of the fracture-mortality relationship and the effect of treatment on this mortality for different fracture types and in different populations by integrating data from multiple international epidemiology studies of osteoporosis.
Fundamental flaws in the design and reporting of research outcomes can undermine evidence-based medicine, impede patient-centred care, cause harm to patients, and result in a waste of research dollars. Our 3-year multinational project engages with patients, caregivers, clinicians, researchers and policy makers, to establish core outcomes in haemodialysis. This will ensure that patient-centred outcomes are consistently measured and reported in haemodialysis trials and other forms of research.
Chronic Kidney Disease: Natural History Of Disease, Cost And Quality Of Life
Funder
National Health and Medical Research Council
Funding Amount
$72,281.00
Summary
Chronic kidney disease (CKD) is present in 12% of Australians aged over 25. CKD is associated with poor health outcomes including cardiovascular disease and progression to End Stage Kidney Disease. Many questions about CKD remain. My research aims to increase our understanding of the natural history of CKD in the Australian population, with focus on outcomes of CKD progression, cardiovascular and all-cause mortality, quality of life, and costs to society.
The Burden Of Late Preterm Birth On Brain Development And 2 Year Outcomes – A Prospective, Longitudinal Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$838,690.00
Summary
80% of preterm babies are born from 32-36 weeks’ gestation, and are late preterm (LPT). LPT children have more learning problems, but why this occurs is unknown. This study aims to understand the effect of LPT birth on brain development. We will do brain scans at term and assess development at 2 years of age of 200 LPT and 200 full-term children. We expect LPT babies will have subtle alterations in brain development compared with term controls which will be associated with delayed development.
Structure and states of operator-algebraic dynamical systems. This project is in the general area of functional analysis, and more specifically operator theory, an area in which the University of Wollongong has an active research group and a strong international reputation. The investigators will study dynamical systems arising in combinatorial and number-theoretic situations, where the analogue of the "dynamics'' is provided by an action of the real line on an operator algebra. Thus the project ....Structure and states of operator-algebraic dynamical systems. This project is in the general area of functional analysis, and more specifically operator theory, an area in which the University of Wollongong has an active research group and a strong international reputation. The investigators will study dynamical systems arising in combinatorial and number-theoretic situations, where the analogue of the "dynamics'' is provided by an action of the real line on an operator algebra. Thus the project will involve ideas and techniques from a wide range of mathematical disciplines, and will help to broaden Australia's expertise across these disciplines.Read moreRead less
Endomorphisms, transfer operators and Hilbert modules. This project is in the general area of functional analysis, an area where both Newcastle University and the University of New South Wales have strong international reputations. The aim of the project is to study irreversible dynamics in the presence of transfer operators, as recently introduced by Professor Exel. The motivation comes from a variety of examples arising in different areas of mathematics, including number theory and graph theor ....Endomorphisms, transfer operators and Hilbert modules. This project is in the general area of functional analysis, an area where both Newcastle University and the University of New South Wales have strong international reputations. The aim of the project is to study irreversible dynamics in the presence of transfer operators, as recently introduced by Professor Exel. The motivation comes from a variety of examples arising in different areas of mathematics, including number theory and graph theory. It is hoped that the results will give new understanding of the algebraic and analytic structure underlying the multi-resolution analyses used in approximation theory and Fourier analysis. This project will help ensure that Australia has a strong foundation in mathematics which will foster innovation.Read moreRead less
Representations of dynamical systems, amenability, and proper actions. Mathematicians study abstract objects by representing them in terms of well-understood concrete models, and need to know when a representation is faithful, in the sense that the model contains complete information. Dynamical systems are an abstraction of physical systems suitable for studying time evolution and symmetries. The project aims to determine when important representations of dynamical systems are faithful, or, in ....Representations of dynamical systems, amenability, and proper actions. Mathematicians study abstract objects by representing them in terms of well-understood concrete models, and need to know when a representation is faithful, in the sense that the model contains complete information. Dynamical systems are an abstraction of physical systems suitable for studying time evolution and symmetries. The project aims to determine when important representations of dynamical systems are faithful, or, in mathematical language, when the dynamical system is amenable. The proposed strategy involves extending Rieffel's notion of proper actions; the construction should be of wide applicability apart from the intended applications to amenability.Read moreRead less
Operator algebras associated to semigroups and graphs. This project aims to unify ideas from two highly topical areas of mathematics in which one studies discrete objects by representing them as families of linear transformations. In the first area, one represents the semigroups which model irreversible dynamics as isometries (that is, distance-preserving transformations); in the second, one represents networks by families of partially defined isometries in a way which reflects the behaviour of ....Operator algebras associated to semigroups and graphs. This project aims to unify ideas from two highly topical areas of mathematics in which one studies discrete objects by representing them as families of linear transformations. In the first area, one represents the semigroups which model irreversible dynamics as isometries (that is, distance-preserving transformations); in the second, one represents networks by families of partially defined isometries in a way which reflects the behaviour of paths in the network. The link will be achieved by viewing the operator algebras they generate as semidirect products which have been twisted by a noncommutative cocycle.Read moreRead less
The structure of quantum groups. We propose to study the structure of mathematical objects used in describing symmetries of micro-scale phenomena. The project will significantly develop already well established Australian-Korean cooperation in this exciting and rapidly growing area of research. The results will be immediately applicable to related fields of mathematics, most notably to noncommutative geometry. In the long run, the outcomes will help in better understanding of fundamental problem ....The structure of quantum groups. We propose to study the structure of mathematical objects used in describing symmetries of micro-scale phenomena. The project will significantly develop already well established Australian-Korean cooperation in this exciting and rapidly growing area of research. The results will be immediately applicable to related fields of mathematics, most notably to noncommutative geometry. In the long run, the outcomes will help in better understanding of fundamental problems of modern quantum physics.Read moreRead less
Operator algebras associated to groupoids. Australian researchers have a strong reputation for excellence and innovation in the field of operator algebras. Operator algebras associated to groupoids have been immensely influential in recent decades, both within mathematics and via applications to theoretical physics. This project will develop an innovative approach to groupoid algebras, and will help to maintain the high standing of Australian researchers in this important field.