Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Founders and survivors: Australian lifecourses in historical context. This project will create one of the world's outstanding longitudinal studies of human health and resilience. It will contribute to the historical understanding of European migration, settler colonialism, forced labour and human health under stress, long-run family formation and falling fertility, household economy, and the social determinants of health. It will contribute to debate both nationally and internationally on the lo ....Founders and survivors: Australian lifecourses in historical context. This project will create one of the world's outstanding longitudinal studies of human health and resilience. It will contribute to the historical understanding of European migration, settler colonialism, forced labour and human health under stress, long-run family formation and falling fertility, household economy, and the social determinants of health. It will contribute to debate both nationally and internationally on the long-run effects of social and biomedical interventions and of investment in human capital. It will tell the grassroots history of the Australian penal and colonial experiments and it will form a scholarly coalition with the great community of family historians. Read moreRead less
Novel geometric invariants. Quantum theory is the language of fundamental physics, it describes the small scale structure of matter and possibly space-time. Sophisticated models in condensed matter physics and string theory have exposed geometric and topological structure as basic building blocks of the theory. Issues thrown up by quantum theory are very similar to, and have provided techniques to solve, problems in the geometry of three and four dimensional manifolds. Exciting two way exchanges ....Novel geometric invariants. Quantum theory is the language of fundamental physics, it describes the small scale structure of matter and possibly space-time. Sophisticated models in condensed matter physics and string theory have exposed geometric and topological structure as basic building blocks of the theory. Issues thrown up by quantum theory are very similar to, and have provided techniques to solve, problems in the geometry of three and four dimensional manifolds. Exciting two way exchanges of methods, problems and solutions have emerged. This project aims to settle fundamental questions in the interaction between these two fields.Read moreRead less
Asymptotic Geometric Analysis and Learning Theory. Learning Theory is used in various real-world applications in diverse research areas, ranging from Biology (e.g. DNA sequencing) to Information Sciences. Therefore, having a deep understanding of fundamental questions in Learning Theory, and in particular, pin-pointing the parameters that make a learning problem hard would have a significant practical impact. This projects aims to achieve this goal, and in addition, we expect it would have a hig ....Asymptotic Geometric Analysis and Learning Theory. Learning Theory is used in various real-world applications in diverse research areas, ranging from Biology (e.g. DNA sequencing) to Information Sciences. Therefore, having a deep understanding of fundamental questions in Learning Theory, and in particular, pin-pointing the parameters that make a learning problem hard would have a significant practical impact. This projects aims to achieve this goal, and in addition, we expect it would have a high theoretical value, as the questions we shall address are of independent interest to pure mathematicians.Read moreRead less
What is normal brain ageing? An investigation of changes in brain structure and cognition in mid-life. Pathological brain changes associated with cognitive decline later in life become detectable in the 40s and sometimes earlier, yet little is known about what constitute normal brain ageing in midlife. Using a number of neuroimaging techniques, this project will develop a detailed map of brain and cognitive ageing in middle-age and their predictors.
Asymptotic Geometric Analysis and Learning Theory. Learning Theory is used in various real-world applications in diverse research areas, ranging from Biology (e.g. DNA sequencing) to Information Sciences. Therefore, having a deep understanding of fundamental questions in Learning Theory, and in particular, pin-pointing the parameters that make a learning problem hard would have a significant practical impact. This projects aims to achieve this goal, and in addition, we expect it would have a hig ....Asymptotic Geometric Analysis and Learning Theory. Learning Theory is used in various real-world applications in diverse research areas, ranging from Biology (e.g. DNA sequencing) to Information Sciences. Therefore, having a deep understanding of fundamental questions in Learning Theory, and in particular, pin-pointing the parameters that make a learning problem hard would have a significant practical impact. This projects aims to achieve this goal, and in addition, we expect it would have a high theoretical value, as the questions we shall address are of independent interest to pure mathematicians.
Read moreRead less
The role of short tandem repeat DNA variation in the evolution of human psychological diversity. The proposed work addresses fundamental questions about human nature. It ties together the evolutionary processes that have shaped us as a species with the way our genes influence: our personalities, the way we think and how we behave. It introduces a novel approach to addressing questions about the role of genetics in human variation that will contribute substantially to the way we understand, perce ....The role of short tandem repeat DNA variation in the evolution of human psychological diversity. The proposed work addresses fundamental questions about human nature. It ties together the evolutionary processes that have shaped us as a species with the way our genes influence: our personalities, the way we think and how we behave. It introduces a novel approach to addressing questions about the role of genetics in human variation that will contribute substantially to the way we understand, perceive and manage important aspects of human diversity.Read moreRead less
Assessing Bone Quality and Health: Experimental imaging, structural characterisation, and mechanical modelling of bone in 3D. Age-related bone fractures due to osteoporosis impose a significant social and economic problem on our increasingly aging population. The assessment of bone quality is important in the diagnosis of age related bone fragility and for studying the efficacy of therapeutic intervens. In this proposal a unique interdisciplinary group with expertise in bone and mineral research ....Assessing Bone Quality and Health: Experimental imaging, structural characterisation, and mechanical modelling of bone in 3D. Age-related bone fractures due to osteoporosis impose a significant social and economic problem on our increasingly aging population. The assessment of bone quality is important in the diagnosis of age related bone fragility and for studying the efficacy of therapeutic intervens. In this proposal a unique interdisciplinary group with expertise in bone and mineral research, experimental 3D imaging and the characterisation and modelling of complex materials will tackle the problem of assessing bone quality and health. The proposed research will greatly improve our assessment of the mechanical competence of bone.Read moreRead less
Social exclusion and teenage motherhood in Australia. Our current understanding of teenage motherhood paints a very grim picture of the lives of teenage mothers and their babies. An over-reliance on the welfare system and social isolation lead to inadequate opportunities for education, employment and productive relationships and are responsible for enhancing social exclusion and weakening a society's social and economic fabric. This project provides great benefit to both the Australian community ....Social exclusion and teenage motherhood in Australia. Our current understanding of teenage motherhood paints a very grim picture of the lives of teenage mothers and their babies. An over-reliance on the welfare system and social isolation lead to inadequate opportunities for education, employment and productive relationships and are responsible for enhancing social exclusion and weakening a society's social and economic fabric. This project provides great benefit to both the Australian community and individual teenage mothers and their children. A deeper understanding will lead to better design of support systems and programs for young mothers and their children.Read moreRead less
Development of nanoporous materials for capture and release of oxygen. This project aims to develop new materials to make lighter, more efficient oxygen concentrators. The project will combine materials that can capture oxygen with particles that can be magnetically heated, making it possible to release the oxygen rapidly and efficiently when needed. Expected outcomes from this project include new composite materials and better understanding of how gases are trapped and released within composite ....Development of nanoporous materials for capture and release of oxygen. This project aims to develop new materials to make lighter, more efficient oxygen concentrators. The project will combine materials that can capture oxygen with particles that can be magnetically heated, making it possible to release the oxygen rapidly and efficiently when needed. Expected outcomes from this project include new composite materials and better understanding of how gases are trapped and released within composite materials. Benefits from this project may include oxygen concentrators that are more portable and have longer battery life, both with industrial and medical applications.Read moreRead less