ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Cooperative control of networked systems with constraints. This project aims to address the challenge of networked systems in deploying teams of robotic agents. Control of the networked system is extremely difficult due to real world constraints imposed on each agent. This project will focus on motion constraints, equipment/capability constraints, and spatial constraints. In addition to theoretical advances, the wider scientific community will benefit directly, because the control algorithms dev ....Cooperative control of networked systems with constraints. This project aims to address the challenge of networked systems in deploying teams of robotic agents. Control of the networked system is extremely difficult due to real world constraints imposed on each agent. This project will focus on motion constraints, equipment/capability constraints, and spatial constraints. In addition to theoretical advances, the wider scientific community will benefit directly, because the control algorithms developed are expected to allow straightforward deployment of robotic teams. There are myriad applications for cooperative robotic agents, ranging from surveillance, to environmental monitoring using underwater and aerial drone formations – with an array of benefits and impacts including economic, commercial and societal. The results are intended to ensure and cement Australia’s front-line position in the current technological revolution known as “Industry 4.0”.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989071
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Phytosphere: new facilities for controlled manipulation of effects of climate change & airborne pollutants on disease epidemiology & plant performance. Western Australia is home to a range of world-leading plant science research groups. Establishing a world-class multi-purpose phytosphere facility in WA will enable these groups to remain at the forefront of their research fields and continue to attract high-profile international scientists and students. Such a facility will result in significant ....Phytosphere: new facilities for controlled manipulation of effects of climate change & airborne pollutants on disease epidemiology & plant performance. Western Australia is home to a range of world-leading plant science research groups. Establishing a world-class multi-purpose phytosphere facility in WA will enable these groups to remain at the forefront of their research fields and continue to attract high-profile international scientists and students. Such a facility will result in significant advancement of our understanding of the impact of climate change on plants through biotic stresses (e.g., disease epidemiology, plant-pathogen interactions) and in interaction with abiotic variables (e.g., CO2 concentrations, temperature, light intensity, humidity, moisture stress, airborne pollutants such as SO2), and allow crop yield optimisation in future environments.Read moreRead less
TELEPHONE COUNSELLING FOR MAINTENANCE OF PHYSICAL ACTIVITY, WEIGHT LOSS And GLYCAEMIC CONTROL IN TYPE 2 DIABETES
Funder
National Health and Medical Research Council
Funding Amount
$1,285,894.00
Summary
Regular exercise, a healthy diet and weight loss are key to managing type 2 diabetes, yet these are major challenges for most people with diabetes. This study will evaluate the impact of a telephone counselling program to assist people with type 2 diabetes to exercise, eat a healthy diet and lose weight, with the goal of helping them to sustain these changes over the long-term. It is expected that these lifestyle changes will also result in improved blood glucose control and quality of life.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0667981
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad ran ....Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad range of research programs. The development of this software program therefore has the potential to benefit research scientists, academics and students in many related fields, as well as the broader community, through enhancing research outcomes.Read moreRead less
Special Research Initiatives - Grant ID: SR0354908
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outco ....The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outcomes and solutions to problems in agriculture, horticulture, forestry and protection of Australia's native flora. Researchers are struggling to create these links, constrained by disciplinary boundaries and geographical isolation. Key industries and researchers already support this proposal.Read moreRead less
Control and Optimization of Distributed Multiagent Formations. The project aims to develop a conceptual framework and algorithms for handling multi-vehicle formation control. Formations of unmanned airborne vehicles are currently used by defence forces and swarms of micro-vehicles are beginning to find increasing use in defence and for civilian emergency response, largely for surveillance purposes. Vehicles must cooperate to achieve a global formation objective, while respecting constraints on s ....Control and Optimization of Distributed Multiagent Formations. The project aims to develop a conceptual framework and algorithms for handling multi-vehicle formation control. Formations of unmanned airborne vehicles are currently used by defence forces and swarms of micro-vehicles are beginning to find increasing use in defence and for civilian emergency response, largely for surveillance purposes. Vehicles must cooperate to achieve a global formation objective, while respecting constraints on sensors, energy, and general mechanical limitations. The project aims to resolve the challenges of deciding what a single vehicle should observe, what and to where it should communicate, and how it should move in relation to what it sees. The conceptual framework developed may also be relevant in guiding future defence acquisitions and civilian applications.Read moreRead less
ARC Centre of Excellence - In Plant Energy Biology (CPEB). Plant cell metabolism underlies the synthesis of important products in crops, and subtle changes in metabolism can enhance germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Research in CPEB will focus on control of this metabolism. Its expertise will enhance Australia's participation in major international research efforts directly relevant to sustainable agriculture in a country with fragile/ ....ARC Centre of Excellence - In Plant Energy Biology (CPEB). Plant cell metabolism underlies the synthesis of important products in crops, and subtle changes in metabolism can enhance germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Research in CPEB will focus on control of this metabolism. Its expertise will enhance Australia's participation in major international research efforts directly relevant to sustainable agriculture in a country with fragile/degrading ecosystems. The research will provide new approaches for enhancing quality metabolite traits important for human health. It will further strengthen our international leadership in plant energy science, and will strengthen Australia's research training in systems biology to influence plant function.Read moreRead less
A hierarchical quantum mechanical and classical simulation of biological ion channels. I aim to develop a methodology incorporating molecular quantum
mechanics and classical Brownian mechanics in a way that can be
applied practically to large macromolecular systems, thus relating
fine structural details to experimentally measurable
properties. Specifically, I will apply this methodology to study ion
channels in which the challenge is to relate electronic and atomic
structure to the conduct ....A hierarchical quantum mechanical and classical simulation of biological ion channels. I aim to develop a methodology incorporating molecular quantum
mechanics and classical Brownian mechanics in a way that can be
applied practically to large macromolecular systems, thus relating
fine structural details to experimentally measurable
properties. Specifically, I will apply this methodology to study ion
channels in which the challenge is to relate electronic and atomic
structure to the conductance properties of the channel. Accurately
determining these relationships provides a pathway to developing cures
for many neurological, cardiac, and muscular diseases.
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