Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous ....Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous environmental and biomedical research is built. Social impact will be seen in the training of a new generation of integrative genome biologists, and the shaping of attitudes toward the role of genetics in human biology.Read moreRead less
Regulation of ion homeostasis by two-component signalling elements. Dryland salinity is continuously claiming Australian lands and is a serious threat to our agricultural industry, native flora and fauna, and infrastructure. Attempting to feed an increasing population whilst agricultural land is disappearing, places an ever-increasing burden on our remaining land. While there is no simple solution to this problem, understanding how plants regulate cellular ion concentrations will help to generat ....Regulation of ion homeostasis by two-component signalling elements. Dryland salinity is continuously claiming Australian lands and is a serious threat to our agricultural industry, native flora and fauna, and infrastructure. Attempting to feed an increasing population whilst agricultural land is disappearing, places an ever-increasing burden on our remaining land. While there is no simple solution to this problem, understanding how plants regulate cellular ion concentrations will help to generate plants that are suitable for restoration of damaged lands or crop plants that are more tolerant to saline soils. Furthermore, knowledge acquired from the proposed project will also be useful for generating healthier crop plants with enhanced levels of ions essential for the human diet. Read moreRead less
Socioeconomic inequality and diet: a multilevel study of why socioeconomic groups differ in their food purchasing behaviours. Socioeconomically disadvantaged groups experience higher mortality and morbidity rates for many chronic diseases (e.g. heart disease and type 2 diabetes). Dietary quality, and factors affecting this such as food purchasing choice, play a key role in the onset and progression of these types of diseases, and the lower quality diets of families from disadvantaged backgrounds ....Socioeconomic inequality and diet: a multilevel study of why socioeconomic groups differ in their food purchasing behaviours. Socioeconomically disadvantaged groups experience higher mortality and morbidity rates for many chronic diseases (e.g. heart disease and type 2 diabetes). Dietary quality, and factors affecting this such as food purchasing choice, play a key role in the onset and progression of these types of diseases, and the lower quality diets of families from disadvantaged backgrounds contribute to their poorer health. This Project will determine why socioeconomic groups differ in their food purchasing behaviours, by examining the influence of environmental and individual-level factors. Project findings will increase our understanding about socioeconomic differences in diet, and inform public policy, health policy, and health promotion.Read moreRead less
Role of ferroxidases in intestinal iron transport. This project will investigate the mechanism by which the body absorbs the essential nutrient iron from the diet. These studies will enhance our knowledge of an important nutritional pathway and improve our capacity to treat diseases where iron absorption is defective, such as the iron loading disorder haemochromatosis.