Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions w ....Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions will be re-evaluated in the context of contemporary economic, social and environmental criteria to enable existing multi-criteria models to deliver more sustainable outcomes that are also feasible and in the national interest, and consequently minimise the industry's current exposure to future climate change.Read moreRead less
Remembering the Wars: Community Significance of Western Australian War Memorials. The project will provide an enriched understanding of war commemoration, community meanings, the design of war memorials and recommendations of practical strategies for their interpretation and conservation. The research from this project will add to the social understanding of our national war commemorative practices, the connections between community meaning and memorial design and the importance of war memorials ....Remembering the Wars: Community Significance of Western Australian War Memorials. The project will provide an enriched understanding of war commemoration, community meanings, the design of war memorials and recommendations of practical strategies for their interpretation and conservation. The research from this project will add to the social understanding of our national war commemorative practices, the connections between community meaning and memorial design and the importance of war memorials as instruments of citizenship. Results will be used to formulate a strategy to raise regional community awareness and regard for local war memorials through publications and through the direct action of local RSL Branches and community interest groups with a view to application on a national scale through the RSL. Read moreRead less
The molecular role of ADAM12 in maintenance of skeletal muscle, myogenesis and adipogenesis. An understanding of the molecular control of skeletal muscle growth, maintenance and balance between muscle and fat production is of fundamental importance for a competitive meat industry, for the promotion of strong muscles in the ageing population and for disorders such as muscle diseases, diabetes and obesity. This project will enhance strong international collaborations and expand cutting-edge resear ....The molecular role of ADAM12 in maintenance of skeletal muscle, myogenesis and adipogenesis. An understanding of the molecular control of skeletal muscle growth, maintenance and balance between muscle and fat production is of fundamental importance for a competitive meat industry, for the promotion of strong muscles in the ageing population and for disorders such as muscle diseases, diabetes and obesity. This project will enhance strong international collaborations and expand cutting-edge research within Australia with many potential economic benefits for the meat industry, biotechnology and health. The expertise developed by this pioneering research will ensure that Australia is well placed to harness new technologies and exploit future advances in this fast-moving field of muscle biology.Read moreRead less
Catastrophe: a historical and philosophical assessment of urban disaster, ethics and the built environment. This project provides a comprehensive framework for the re-evaluation of civil society in relation to the built environment. It proposes that ‘safeguarding Australia’ and understanding its place in the world can begin by looking at urban planning and architecture, the perceptions that define them, and the catastrophic risks that attend them.
Presumed Guilty: An Economics Analysis of the Efficiency of Environmental Bonds for the WA Mining Sector. Environmental bonds have two important economic effects. First they give an incentive for mining firms to manage environmental damage and second they prevent excessive costs falling on the regulator in the case of bankruptcy. The aim of this project is to assess if this policy can be redesigned to increase its economic efficiency.
Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this fram ....Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this framework in improving schools will be shown using a new approach to make school facilities deliver educational outcomes and account for their total production and transaction costs. This research is expected to deliver more efficient ways to future-proof schools to create a well performing school system and more resilient infrastructure vital to Australia’s future prosperity.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Role Of Hepatic Stellate Cell And Liver Progenitor Cell Interactions In The Regulation Of Wound Healing And Liver Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$620,716.00
Summary
The liver has a remarkable capacity for regeneration following acute and chronic liver injury, however, the mechanisms which facilitate this wound healing are not understood. This project will examine the interactions between different liver cell populations, including hepatic stellate cells (liver fibroblasts) and liver progenitor cells (stem cells of the liver) and will determine which factors regulate inflammation, liver scarring and restitution of liver mass following chronic liver injury.
An interdisciplinary framework for place-based research and its impact on the tourist industry. The project situates Australian research at the heart of an interdisciplinary inquiry into the understanding of place, and its socio-cultural analysis. It promotes national research on the interpretation of place in social analysis, and the publications produced respond to commercial needs for high-level interpretative place-based studies in the tourism industry. The generation of intellectually rigor ....An interdisciplinary framework for place-based research and its impact on the tourist industry. The project situates Australian research at the heart of an interdisciplinary inquiry into the understanding of place, and its socio-cultural analysis. It promotes national research on the interpretation of place in social analysis, and the publications produced respond to commercial needs for high-level interpretative place-based studies in the tourism industry. The generation of intellectually rigorous knowledge capital for outbound educational tour operators locates Australia at the intellectual cutting edge of scholarly content for educational tourism and for heritage organizations worldwide. The project is explicitly designed to provide early career training, with opportunities for research on the tourist industry.Read moreRead less
The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuil ....The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuilding.Read moreRead less