Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100028
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes ....Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes include understanding past global environmental change on multiple time scales, the deep biosphere, plate tectonics, formation and distribution of resources, and generation of hazards. These outcomes are paramount to Australia’s national science and research priorities, and societal and economic prosperity.Read moreRead less
A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.
Special Research Initiatives - Grant ID: SR0354908
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outco ....The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outcomes and solutions to problems in agriculture, horticulture, forestry and protection of Australia's native flora. Researchers are struggling to create these links, constrained by disciplinary boundaries and geographical isolation. Key industries and researchers already support this proposal.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100203
Funder
Australian Research Council
Funding Amount
$385,000.00
Summary
Autonomous benthic observing system. This project seeks to improve our ability to monitor marine habitats and characterise their variability by enhancing the Integrated Marine Observing system (IMOS) Autonomous Underwater Vehicle (AUV) Facility. The new AUV infrastructure will reduce operating costs, increase robustness of the sampling effort and insure continued operation for the next decade.
Coupled physical and biogeochemical dynamics on the Australian North West Shelf. Information regarding the natural function of the Australian North West Shelf is urgently required to sustainably manage the often conflicting uses of the region. This project will study the role of ocean processes in driving ocean productivity on the North West Shelf and determine the impact of projected climate variability.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100219
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate k ....A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate key questions in oceanography and the mining and energy, archaeological, agricultural, and forestry sectors. The facility is expected to substantially increase expertise and training in radionuclides in Australia, and promote high-level research collaborations and outputs of both national and international significance. Major outcomes of the proposed facility include better understanding of how oceans regulate climate and improved capacity to assess effects of radiation on natural ecosystems.Read moreRead less
Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have change ....Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have changed over long periods of time is vital to understanding the nature of the system itself. The project intends to track changes in the diet of Adélie penguins from serially preserved ancient fecal (guano) remains dating back approximately 30,000 years. These remains are known to contain microscopic remnants of penguin prey.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100019
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
A transportable containerised laboratory for rapid cell sorting and high-resolution bioimaging of living aquatic microbes in field locations. This project will deliver a transportable, unique laboratory for the rapid isolation and high-resolution analysis of living microbes immediately after sampling from the sea or waterways. It will be the first of its kind in Australia and deliver new knowledge of the role of these organisms in their natural habitats.