Tropical Diseases: Translating Discoveries Into Better Health
Funder
National Health and Medical Research Council
Funding Amount
$19,803,660.00
Summary
Major progress being made in control of many infectious diseases occurring in tropical areas, including malaria worms and the bacteria that causes strep throat. However, currently available tools will not permit their full control or elimination. This program is aimed to improve understanding of these diseases and to develop the much needed tools that will be required for their elimination.
Tropical Disease - Immunity, Pathogenesis And Vaccine Development: Global Translation
Funder
National Health and Medical Research Council
Funding Amount
$17,988,456.00
Summary
Tropical diseases create a significant human and economic burden worldwide - particularly in resource-poor settings. Around half of the world's population is at risk of malaria. In Australia, Streptococcal and parasitic worm infections are particularly common in indigenous communities. This Program brings together leading experts to tackle these major health challenges. They are investigating how the body reacts to infection and creating new drugs and vaccines to eradicate these diseases.
The lymphocyte plays a vital role in our immune defence. When lymphocytes encounter a foreign invader, such as a virus, they make a series of decisions that influence the strength, type, and longevity of the immunity created. This program aims to understand how lymphocytes make decisions at the molecular level that affect cell and whole of system level behaviour. We aim to improve vaccines and understand diseases such as allergy, lupus, arthritis and leukaemia to develop novel therapies.
Uncovering The Basis Of Inflammatory And Immunodeficiency Diseases
Funder
National Health and Medical Research Council
Funding Amount
$15,718,075.00
Summary
A world-class team from 3 institutions, spanning disciplines of clinical and experimental immunology, therapeutics, signalling and genetics, will identify how immune and inflammatory responses are controlled in both health and disease. The major outcomes of this work will be the generation of new knowledge, concepts and approaches to diagnose, prevent and treat the major human health problems of autoimmune diseases, inflammation, allergy and immunodeficiency.