Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Discovery Early Career Researcher Award - Grant ID: DE230101128
Funder
Australian Research Council
Funding Amount
$444,154.00
Summary
Decode Neuro-Mechanobiology:mechanosensitive ion channels in proprioception. Human bodies are densely covered with numerous mechanosensory neurons that provide us with the sense of touch and pain. However, the molecular force sensors remain poorly identified. This project aims at defining the fundamental roles of mechanosensitive ion channels to sense and respond to various mechanical stimuli, and how their responses may encode mechanical cues.The ultimate goal is to provide a fundamentally new ....Decode Neuro-Mechanobiology:mechanosensitive ion channels in proprioception. Human bodies are densely covered with numerous mechanosensory neurons that provide us with the sense of touch and pain. However, the molecular force sensors remain poorly identified. This project aims at defining the fundamental roles of mechanosensitive ion channels to sense and respond to various mechanical stimuli, and how their responses may encode mechanical cues.The ultimate goal is to provide a fundamentally new understanding of proprioception and motion sensing. The new multimodality approach generated in this project is expected to evolve as a national facility for neuro-mechanobiology, and future research may lead to the inspiration of novel bionic sensor design and brain-computer interface for future neuroengineering industry.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100609
Funder
Australian Research Council
Funding Amount
$368,000.00
Summary
Mechanobiology: a new model of integrin activation by membrane tension. This project aims to address a fundamental question in mechanobiology on how integrin receptor coordinates with force to mediate cell spreading, migration, growth and survival. With an observation that membrane deformation enhances integrin binding, the project expects to establish a new model of integrin activation by membrane tension. It will develop an integrated approach combining single-molecule force probes, super reso ....Mechanobiology: a new model of integrin activation by membrane tension. This project aims to address a fundamental question in mechanobiology on how integrin receptor coordinates with force to mediate cell spreading, migration, growth and survival. With an observation that membrane deformation enhances integrin binding, the project expects to establish a new model of integrin activation by membrane tension. It will develop an integrated approach combining single-molecule force probes, super resolution microscopy, microfluidics and molecular dynamics simulations. It is expected that the role of membrane tension in promoting cell adhesion will be defined at molecular scale, and the link between integrin activation and Piezo calcium channel mediated membrane tension sensing will be delineated.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100487
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Thermal hotspots detection in nanoscale two-dimensional electronics. The emergence of flexible nanoelectronics holds the promise to impact the way we live—from smart wearables to foldable smartphones. However, heat dissipation in the atomically-thin materials used for their conception has remained poorly understood due to their planar structures. This project aims at the detection and mapping of nanoscale thermal hotspots in flexible nanoelectronics devices using a two-dimensional-based optical ....Thermal hotspots detection in nanoscale two-dimensional electronics. The emergence of flexible nanoelectronics holds the promise to impact the way we live—from smart wearables to foldable smartphones. However, heat dissipation in the atomically-thin materials used for their conception has remained poorly understood due to their planar structures. This project aims at the detection and mapping of nanoscale thermal hotspots in flexible nanoelectronics devices using a two-dimensional-based optical thermometer. The expected outcome of this project is the development of a non-invasive thermometric technology that enables locating these critical nanoscale hotspots with nanoscale precision. This will lead to better design and manufacturing strategies for heat dissipation in these devices.Read moreRead less
Liquid crystal-based optical fibre hydrophone system for underwater surveillance and ocean monitoring. The aim of this project is to design, implement and optimise a new class of optical sensing system which targets underwater surveillance and ocean monitoring. This project is expected to lead to improved national security, broaden Australia's photonics knowledge base, and contribute to greater international scientific collaboration.