The Role Of The Cytosolic Pathogen Recognition Molecule Nod1 In Host Responses To Helicobacter Pylori Infection.
Funder
National Health and Medical Research Council
Funding Amount
$82,753.00
Summary
Helicobacter pylori is the causative agent of gastric ulcers and cancer. However, many questions remain unanswered regarding how H. pylori causes gastric disease. We have recently identified the receptor Nod1 as an important factor in the ability of this bacterium to induce inflammation. The major aim of this project is to investigate the role of Nod1 in the innate and adaptive immune responses to this pathogen.