Assessing The Benefit Of Low Dose Aspirin In The Prevention Of Severe Sepsis.
Funder
National Health and Medical Research Council
Funding Amount
$391,880.00
Summary
Recent discoveries suggest that low doses of aspirin may save lives in patients with infection by limiting its severity. We will conduct a large-scale primary prevention study using daily low-dose aspirin to explore whether this widely used drug can safely prevent severe infection. This study is made possible by collaborative involvement in an existing Australian and USA funded study called ASPREE. Finding a treatment that helps prevent severe effects and outcomes of infection would be a major h ....Recent discoveries suggest that low doses of aspirin may save lives in patients with infection by limiting its severity. We will conduct a large-scale primary prevention study using daily low-dose aspirin to explore whether this widely used drug can safely prevent severe infection. This study is made possible by collaborative involvement in an existing Australian and USA funded study called ASPREE. Finding a treatment that helps prevent severe effects and outcomes of infection would be a major health advance.Read moreRead less
Born A Bit Early: Long-term Child Educational And Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$597,170.00
Summary
This will be a population level study covering all children born in New South Wales between 1994 and 2010. The size of the study population will be approximately 1.5 million children. The ratio of males to females will be approximately 1:1.
Cardiac Resynchronisation Therapy And AV Node Ablation For Atrial Fibrillation In Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$3,274,979.00
Summary
Heart failure (HF) and Atrial Fibrillation (AF) are both significant health issues that often coexist. Cardiac resynchronisation therapy (CRT) is a proven therapy for HF with ventricular dyssynchrony (uncoordinated contraction of the left ventricle). While CRT reduces symptoms and improves survival in normal rhythm, there are mixed reports in patients with AF. This prospective randomised multicentre study, will assess the role of AV node ablation to improve outcomes in CRT in AF.
Improving Access To Primary Care For Aboriginal Babies In Western Australia. The ‘Stork’ Population Based Cluster Randomised Trial.
Funder
National Health and Medical Research Council
Funding Amount
$1,300,459.00
Summary
Over 50% of Western Australian Aboriginal babies are still not receiving preventative care in the early months of life. We will undertake a population based trial of a new integrated model of early infant primary care to improve access and health outcomes for young infants especially infants who live in the most disadvantaged and mobile families. Our primary outcome measure is improved hospitalisation rates in infants aged 0-3 months. Results will be used to develop improved primary care models