Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100068
Funder
Australian Research Council
Funding Amount
$931,950.00
Summary
Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under ....Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under environmental stress; integral chemical signals exchanged in host-microbe interactions; and volatile signatures linked to ecosystem health and developmental anomalies in animals. Results will inform innovative strategies to enhance biological adaptation, climate resilience and plant, animal, and ecosystem health.Read moreRead less
Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new tec ....Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new techniques for acquisition of DNA from museum specimens. The project is expected to provide significant benefits, such as insights into the processes that promote new species in nature.Read moreRead less
Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites ....Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites to survive in the new host. Anticipated outcomes include the identification of new intervention strategies and improved transmission model systems for vector-borne diseases. This gained knowledge could provide benefits to future biomedical applications by informing diagnostics or treatment of lipid associated diseases.Read moreRead less
Linking individual traits, the gut microbiome and parasite load in wildlife. This project aims to apply principles of community ecology to the gut microbiome of an urban exploiter – the common brushtail possum - to reveal how animal traits influence individual variation in the load of gut parasites that cause disease in both humans and wildlife. By combining assays defining the behavioural and physiological states of individuals with sophisticated analyses of their gut microbiome, our project wi ....Linking individual traits, the gut microbiome and parasite load in wildlife. This project aims to apply principles of community ecology to the gut microbiome of an urban exploiter – the common brushtail possum - to reveal how animal traits influence individual variation in the load of gut parasites that cause disease in both humans and wildlife. By combining assays defining the behavioural and physiological states of individuals with sophisticated analyses of their gut microbiome, our project will provide a new, yet crucial, perspective on how and why diseases spread. Our discoveries will help understand and manage the burden of infectious diseases from parasites in and beyond our cities and across the human-wildlife interface; essential for improving human and wildlife health in an increasingly urbanised Australia.Read moreRead less
The Great Disruption of COVID-19: Re-imagining the work-family interface. This project aims to highlight new possibilities to re-imagine and reduce parents’ work-family conflicts. Covid-19 brought an unprecedented disruption to Australian parents' work-care routines, with different effects for women, and those working ‘at work’ versus at home. Using mixed-methods approaches and multiple Australian datasets collected pre- and post-pandemic, this unique project intends to identify families who are ....The Great Disruption of COVID-19: Re-imagining the work-family interface. This project aims to highlight new possibilities to re-imagine and reduce parents’ work-family conflicts. Covid-19 brought an unprecedented disruption to Australian parents' work-care routines, with different effects for women, and those working ‘at work’ versus at home. Using mixed-methods approaches and multiple Australian datasets collected pre- and post-pandemic, this unique project intends to identify families who are at risk of longer-term scarring to family wellbeing from work-care conflicts; and critical workplace supports which may prevent this. Together, this urgently-needed evidence contributes to family-friendly work for diverse parents, employers and policy, protecting social and economic participation for Australian parents.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100672
Funder
Australian Research Council
Funding Amount
$470,337.00
Summary
Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure ....Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure and respond to cognitive workload in the field. This should provide significant benefits such as enhanced performance and safety outcomes, which will provide a strategic advantage to the Australian Defence Force by facilitating the development of advanced technologies that respond to the capabilities of the human user.Read moreRead less