Discovery Early Career Researcher Award - Grant ID: DE240101246
Funder
Australian Research Council
Funding Amount
$379,214.00
Summary
Beyond Big Brother: New Narratives for Understanding Surveillance. This project aims to investigate how recent forms of narrative fiction reflect and shape understandings of digital surveillance. It expects to generate new knowledge about the personal and social implications of digital surveillance across different cultural, technological and geographical contexts. Expected outcomes include a significant interdisciplinary methodology that integrates surveillance studies, digital humanities, and ....Beyond Big Brother: New Narratives for Understanding Surveillance. This project aims to investigate how recent forms of narrative fiction reflect and shape understandings of digital surveillance. It expects to generate new knowledge about the personal and social implications of digital surveillance across different cultural, technological and geographical contexts. Expected outcomes include a significant interdisciplinary methodology that integrates surveillance studies, digital humanities, and literary studies to improve our understanding of surveillance. The project also aims to generate teaching and public engagement resources for research, industry, and government. This will substantially improve our understanding of the impact of digital surveillance at the individual, community, and national levels.Read moreRead less
ARC Asia-Pacific Futures Research Network. The ARC Asia Pacific Futures Network is an international vehicle for building research capacity in the national research system to enhance understanding of Australia, its region, and the world. The Network brings experienced researchers working in identified research areas and themes into dynamic collaboration with government and industry through structured programs, with a view to stimulating new research directions, partnerships and training opportuni ....ARC Asia-Pacific Futures Research Network. The ARC Asia Pacific Futures Network is an international vehicle for building research capacity in the national research system to enhance understanding of Australia, its region, and the world. The Network brings experienced researchers working in identified research areas and themes into dynamic collaboration with government and industry through structured programs, with a view to stimulating new research directions, partnerships and training opportunities. In its 5-year plan, the Network will focus on Governance and Security, Culture and Religion, Media and Communications, Health and Population, and Trade and Industry. APFN will also have the capacity to marshal expertise on pressing issues facing Australia and the region as a whole.Read moreRead less
DNA methylation in insect social evolution. This project will investigate the evolutionary relationship between DNA methylation and the advanced sociality displayed by bees, ants and wasps. The project will map DNA methylation across the social insects and test whether it has coevolved with sociality. It will also determine how a vital social cue, the queen pheromone, influences the worker methylome. Finally, it will apply quantitative genetic and methylomic methods to wild insects, revealing pa ....DNA methylation in insect social evolution. This project will investigate the evolutionary relationship between DNA methylation and the advanced sociality displayed by bees, ants and wasps. The project will map DNA methylation across the social insects and test whether it has coevolved with sociality. It will also determine how a vital social cue, the queen pheromone, influences the worker methylome. Finally, it will apply quantitative genetic and methylomic methods to wild insects, revealing patterns of selection and inheritance in epigenetic and phenotypic traits. By combining genomic and evolutionary methods, the project will advance the ongoing debate about the importance of methylation to sociality and extreme phenotypic plasticity. It will contribute to a quantum leap in our understanding of DNA methylation and sociobiology and mark the first application of quantitative genetics to wild insects.Read moreRead less
ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and ne ....ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and new to nature biological pathways and enzymes. CoESB will combine engineering with molecular biology to design and construct novel biological systems that can convert biomass from agriculture or waste streams to biofuel, bioplastics and other high-value chemicals.Read moreRead less
Discovering sex determining genes in a reptile with genetic and environmental sex determination. Reptile sex determination is particularly fascinating because it is triggered either by genes on sex chromosomes or by the nest temperature. This project will identify and characterise candidate sex determining genes in a model reptile to understand how genes control sexual differentiation and how they interact with temperature.
Using genetics to recover Australia's lost history. This project aims to use historic hair samples collected by anthropological expeditions in the early 20th Century to generate the first genetic map of Aboriginal Australia – in order to reconstruct Australia’s pre-European genetic and cultural past. The map and the detailed contextual and genealogical information from museum archives will assist Aboriginal communities and individuals to reconstruct their personal and family history and trace an ....Using genetics to recover Australia's lost history. This project aims to use historic hair samples collected by anthropological expeditions in the early 20th Century to generate the first genetic map of Aboriginal Australia – in order to reconstruct Australia’s pre-European genetic and cultural past. The map and the detailed contextual and genealogical information from museum archives will assist Aboriginal communities and individuals to reconstruct their personal and family history and trace ancestry and augment oral or written records. The combination of cutting-edge science, detailed archival research, and a comprehensive family outreach and reporting program will be a step change in assisting Australia’s reconciliation process, the Stolen Generation, and repatriation of Indigenous remains.Read moreRead less
Shaping International Law in Global Transformations: Australian Experiences. This project aims to examine how Australia influences the development of international law in times of global transformation. The project proposes to develop a new analytical framework to understand how and why Australia has succeeded (or failed) in shaping the development of international law in four key periods of global transformation. Expected outcomes include empirical studies evaluating how, why and to what extent ....Shaping International Law in Global Transformations: Australian Experiences. This project aims to examine how Australia influences the development of international law in times of global transformation. The project proposes to develop a new analytical framework to understand how and why Australia has succeeded (or failed) in shaping the development of international law in four key periods of global transformation. Expected outcomes include empirical studies evaluating how, why and to what extent Australians managed to shape international law during these periods. These outcomes should provide benefits in the form of evidence-based proposals to enhance Australia's capacity to influence the development of international law in times of global transformation. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100864
Funder
Australian Research Council
Funding Amount
$394,334.00
Summary
Discovering The Effect of alpha-actinin-3 Deficiency on Muscle Adaptations to Exercise Training in Humans. The protein alpha-actinin-3 is expressed in fast muscle fibres. A common gene variant results in complete deficiency in alpha-actinin-3 that has been shown to influence athletic performance. A mouse model has been previously generated to demonstrate that alpha-actinin-3 deficiency results in a significant shift in fast muscle fibres, towards the slow, more efficient muscle fibres. This proj ....Discovering The Effect of alpha-actinin-3 Deficiency on Muscle Adaptations to Exercise Training in Humans. The protein alpha-actinin-3 is expressed in fast muscle fibres. A common gene variant results in complete deficiency in alpha-actinin-3 that has been shown to influence athletic performance. A mouse model has been previously generated to demonstrate that alpha-actinin-3 deficiency results in a significant shift in fast muscle fibres, towards the slow, more efficient muscle fibres. This project will demonstrate the effects of alpha-actinin-3 deficiency on the characteristics of human muscle pre and post exercise training. Outcomes will include major applications for personalising health recommendations and in designing preventative programs for ageing.Read moreRead less
Mechanisms of colour production and the evolution of animal signals. This project aims to reveal how diverse colours are produced in reptiles and the information these colours convey about individual health, condition and performance. The project evaluates how stress affects both pigment deposition and the nano-structure of cells and tissues, which together produce colour. By comparing similar colours generated by two entirely different classes of pigment (carotenoids and pteridines), this proje ....Mechanisms of colour production and the evolution of animal signals. This project aims to reveal how diverse colours are produced in reptiles and the information these colours convey about individual health, condition and performance. The project evaluates how stress affects both pigment deposition and the nano-structure of cells and tissues, which together produce colour. By comparing similar colours generated by two entirely different classes of pigment (carotenoids and pteridines), this project will provide new insights into the evolution of animal coloration, and will significantly enhance our understanding of pteridines, one of the most prevalent but least understood classes of pigment in vertebrates.Read moreRead less
Policy agendas in the Australian Commonwealth Government. Who leads the agenda: the government; the public or the media? Is legislation 'normal business' or a response to crisis? Does changing the government really change much? By systematically analysing legislation, the media and public opinion over a forty year period this project can answer these questions more thoroughly than ever before.