Identification of causal variants for complex traits. The aim of this project is to identify causal variants for complex traits in cattle and humans. Although most important traits in agriculture, medicine and evolution are complex traits, very few of the genetic variants affecting these traits are known and this undermines our understanding of how genetic variants affect a trait and practical uses of this knowledge. Huge datasets of individuals with genome sequence and phenotypes and new statis ....Identification of causal variants for complex traits. The aim of this project is to identify causal variants for complex traits in cattle and humans. Although most important traits in agriculture, medicine and evolution are complex traits, very few of the genetic variants affecting these traits are known and this undermines our understanding of how genetic variants affect a trait and practical uses of this knowledge. Huge datasets of individuals with genome sequence and phenotypes and new statistical methods provide the opportunity to close this gap. The outcome will be identification of many genomic variants causing variation in complex traits. This will benefit scientific understanding of complex traits and the ability to predict traits for individuals from their genome sequence.Read moreRead less
Characterising inheritance patterns of whole genome DNA methylation. This project aims to characterise epigenetic diversity and inheritance patterns in whole genome sequencing data from a unique human population. The project will employ the well-characterised Norfolk Island genetic isolate, cost-effective whole genome bisulphite sequencing technologies and advanced bioinformatics pipelines and statistical models. It will involve cross-discipline collaboration between human geneticists, epigeneti ....Characterising inheritance patterns of whole genome DNA methylation. This project aims to characterise epigenetic diversity and inheritance patterns in whole genome sequencing data from a unique human population. The project will employ the well-characterised Norfolk Island genetic isolate, cost-effective whole genome bisulphite sequencing technologies and advanced bioinformatics pipelines and statistical models. It will involve cross-discipline collaboration between human geneticists, epigeneticists, statistical geneticists and bioinformaticians. This project will advance our understanding of the interaction of genetics and epigenetics and their relationship to diversity and inheritance in humans.Read moreRead less
High-value horticulture and global production networks in coastal Australia. High-value horticulture is booming in Australia’s north-eastern coastal strip, where a multifunctional landscape also provides various recreational, cultural and environmental services. This project aims analyses how incorporation within agricultural global production networks interacts with diverse drivers of landscape change to shape regional development outcomes. This will contribute to global production network theo ....High-value horticulture and global production networks in coastal Australia. High-value horticulture is booming in Australia’s north-eastern coastal strip, where a multifunctional landscape also provides various recreational, cultural and environmental services. This project aims analyses how incorporation within agricultural global production networks interacts with diverse drivers of landscape change to shape regional development outcomes. This will contribute to global production network theory by developing the territorial nexus of these networks. Expected outcomes include improved policy formulations capable of orchestrating a sustainable and equitable future for rural regions and livelihoods within Australia, with broader contributions to understanding rural development pathways elsewhere in the world.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100035
Funder
Australian Research Council
Funding Amount
$4,743,710.00
Summary
ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to devel ....ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to develop ‘smart’ probes and ‘smart’ scanning, harnessing the digital revolution for better, cost effective diagnostic imaging and improved health outcomes.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100001
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end ....ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end users with world-leading interdisciplinary researchers to create new human-AV systems, datasets, frameworks, case studies, platforms, and a vastly upskilled workforce. This will reduce transport costs, increase capacity, boost supply chain efficiency and resilience, improve road safety, and elevate Australian capability.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH220100017
Funder
Australian Research Council
Funding Amount
$4,808,669.00
Summary
ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals. Radiopharmaceuticals are emerging as next generation medical technologies for addressing complex health challenges, and their manufacture offers significant economic benefit to Australia. The ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals (AMTAR) aims to establish a manufacturing platform for new medical technologies combining innovations in biotechnology and pharmaceutical science. The progra ....ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals. Radiopharmaceuticals are emerging as next generation medical technologies for addressing complex health challenges, and their manufacture offers significant economic benefit to Australia. The ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals (AMTAR) aims to establish a manufacturing platform for new medical technologies combining innovations in biotechnology and pharmaceutical science. The program addresses industry-led challenges for translation of biologics as molecular radiopharmaceuticals, building capacity in biomanufacturing, radiobiology and radiochemistry. The program establishes a dedicated manufacturing pipeline, future-proofing production and securing supply chain of next generation medical technologies.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100051
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
The ARC Research Hub for Digital Bioprocess Development. The ARC Hub for Digital Bioprocess Development aims to assist the Biopharma industry by increasing digital innovation, productivity and competitiveness. An interdisciplinary team of engineers, scientists and computing specialists will develop digitally integrated advanced manufacturing processes and a platform for industry adoption. The program will address key bioprocessing research challenges and develop new process and digital models th ....The ARC Research Hub for Digital Bioprocess Development. The ARC Hub for Digital Bioprocess Development aims to assist the Biopharma industry by increasing digital innovation, productivity and competitiveness. An interdisciplinary team of engineers, scientists and computing specialists will develop digitally integrated advanced manufacturing processes and a platform for industry adoption. The program will address key bioprocessing research challenges and develop new process and digital models that can predict and optimise manufacturing processes, resulting in greater yields, faster and more flexible processes and enhanced product stability. The Hub will transform biopharmaceutical manufacturing and unlock growth opportunities to forge an internationally competitive Australian Biopharma sector.Read moreRead less
Socio-cultural Factors and the Use of Therapeutic Opioids in Indonesia. This project aims to determine how legal, policy and socio-cultural factors influence the use of therapeutic opioids in Indonesia. The project expects to generate a nuanced understanding of the impact of non-medical considerations in contested areas of health policy through its multidisciplinary and multi-scalar approach. We expect outcomes to include a robust model of influences on decision-making that can be applied in Ind ....Socio-cultural Factors and the Use of Therapeutic Opioids in Indonesia. This project aims to determine how legal, policy and socio-cultural factors influence the use of therapeutic opioids in Indonesia. The project expects to generate a nuanced understanding of the impact of non-medical considerations in contested areas of health policy through its multidisciplinary and multi-scalar approach. We expect outcomes to include a robust model of influences on decision-making that can be applied in Indonesia and adapted for use in other national contexts. This should provide significant benefits, including an innovative training program to empower doctors and pharmacists to make evidence-based decisions about the potential risks and benefits, both medical and social, of opioid-based treatment options.Read moreRead less
In it to win it: an interdisciplinary investigation of sports betting. This project aims to better understand how young adults use, communicate about and experience mobile phone sports betting applications. Gambling generates significant health and social harms in Australia. Yet there is little research on the use of betting apps, even though sports betting is the fastest growing segment of the gambling market. This project intends to examine how use of sports betting apps is becoming establishe ....In it to win it: an interdisciplinary investigation of sports betting. This project aims to better understand how young adults use, communicate about and experience mobile phone sports betting applications. Gambling generates significant health and social harms in Australia. Yet there is little research on the use of betting apps, even though sports betting is the fastest growing segment of the gambling market. This project intends to examine how use of sports betting apps is becoming established as everyday social practice normalising problem gambling. The findings will enhance understanding of the social contexts of sports betting, and inform gambling policy and programs leading to better health and social outcomes.Read moreRead less