Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.
Group A Streptococcal Human Challenge Study: Accelerating Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$2,018,741.00
Summary
Infection with group A streptococcus (GAS) is a major cause of morbidity and mortality worldwide, including in the Aboriginal population of Australia. Concerted efforts for vaccine development have been hampered by the absence of a suitable animal model. To address this critical knowledge gap we propose to develop a controlled human infection model of GAS infection. This model will provide a direct pathway for the future appraisal of novel GAS vaccines.
Centre Of Research Excellence In Medicines Intelligence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
The NHMRC Centre of Research Excellence in Medicines Intelligence is a co-ordinated research program that will accelerate the development and translation of evidence on prescribed medicines use and outcomes for regulators and payers. The CRE is perfectly placed to embrace the national ‘call to action’ from the Health Minister's recent announcement to establish Quality Use of Medicine Safety as a National Health Priority.
Transnational seafood commodity chains and the coastal poor in the maritime frontiers of the Asia-Pacific. This research aims to understand the social mechanisms by which access to the benefits of transnational seafood commodity chains in the Asia-Pacific are gained, maintained and controlled. This project will use a conceptual framework that focuses on key social relations of gender, class and ethnicity, and the key societal changes of land-use change, migration and conservation. This project o ....Transnational seafood commodity chains and the coastal poor in the maritime frontiers of the Asia-Pacific. This research aims to understand the social mechanisms by which access to the benefits of transnational seafood commodity chains in the Asia-Pacific are gained, maintained and controlled. This project will use a conceptual framework that focuses on key social relations of gender, class and ethnicity, and the key societal changes of land-use change, migration and conservation. This project offers a novel research framework for a pressing cluster of economic, environmental and social challenges in the Asia-Pacific, and will inform research and policy for poverty reduction, economic development, environmental management and food security. Read moreRead less
Contingent development in regional India: ethnographies of neoliberal globalisation in Gujarat and West Bengal. This project aims to understand the regional impacts of globalisation in India by comparing and contrasting two regional towns and their hinterlands (Anand, Gujarat and Darjeeling, West Bengal). Develop a more comprehensive, localised and regionalised account of the neoliberal globalisation process in India.
Where migrants go: A study of immigrants' post-arrival moves in Australia . The project aims to establish the geographical and occupational trajectories of different migrant groups after arrival in Australia. Migration within Australia is a key driver of economic, demographic and social change. Recognising the growing diversity of immigrants, including the rapid rise in temporary migration, the project examines post-arrival moves of immigrants by visa type, country of birth and year of arrival. ....Where migrants go: A study of immigrants' post-arrival moves in Australia . The project aims to establish the geographical and occupational trajectories of different migrant groups after arrival in Australia. Migration within Australia is a key driver of economic, demographic and social change. Recognising the growing diversity of immigrants, including the rapid rise in temporary migration, the project examines post-arrival moves of immigrants by visa type, country of birth and year of arrival. It seeks to improve understanding of the incidence, spatial patterns and drivers of migrants’ movement within Australia and the socio-demographic impact on regions and individuals. Such understanding is an essential first step to the formulation of effective immigration and settlement policies and programs.Read moreRead less
Settling well in regional Australia: Experiences of people from refugee backgrounds. Regional humanitarian settlement is a key priority across all levels of government in Australia. This study aims to provide the first longitudinal assessment of the impacts of regional settlement for humanitarian migrants and destination communities. Its innovative, mixed-method and multi-sited approach will generate new knowledge of the opportunities and challenges for sustainable regional settlement. Expected ....Settling well in regional Australia: Experiences of people from refugee backgrounds. Regional humanitarian settlement is a key priority across all levels of government in Australia. This study aims to provide the first longitudinal assessment of the impacts of regional settlement for humanitarian migrants and destination communities. Its innovative, mixed-method and multi-sited approach will generate new knowledge of the opportunities and challenges for sustainable regional settlement. Expected outcomes include enhanced community, organisational and government decision-making capacity. By guiding end-users’ current and future actions, the study has strong potential to support the wellbeing of humanitarian migrants and to contribute to healthy and resilient regional communities.Read moreRead less
Social implications of market-based policy instruments for carbon and water. This project aims to analyse socio-cultural benefits and risks in the two significant environmental markets of carbon and water across three sites in Australia and Timor-Leste. Research into market-based policies to manage significant environmental issues is yet to fully consider socio-cultural dimensions. This project intends to document local community producers, distant investor and consumer perspectives, and incorpo ....Social implications of market-based policy instruments for carbon and water. This project aims to analyse socio-cultural benefits and risks in the two significant environmental markets of carbon and water across three sites in Australia and Timor-Leste. Research into market-based policies to manage significant environmental issues is yet to fully consider socio-cultural dimensions. This project intends to document local community producers, distant investor and consumer perspectives, and incorporate these perspectives into methods for improving the operation and impact of these expanding markets. By undertaking the first systematic comparison across resources and sites, the project expects to fill a key gap in environmental scholarship and contribute to international strategies to improve social and environmental outcomes in market-based environmental policy.Read moreRead less
Reconceptualising industry sector development within the contemporary Australian city: The case of the information technology sector. This project will aim to uncover the reasons why Australia's Information Technology industry is ranked low among OECD countries by evaluating the impact of global and urban geography of the sector on the sector's performance. It will show how policies to achieve more advanced IT sector development need to consider Australia's distinctive position in the global eco ....Reconceptualising industry sector development within the contemporary Australian city: The case of the information technology sector. This project will aim to uncover the reasons why Australia's Information Technology industry is ranked low among OECD countries by evaluating the impact of global and urban geography of the sector on the sector's performance. It will show how policies to achieve more advanced IT sector development need to consider Australia's distinctive position in the global economy and particular factors in the Sydney and Melbourne IT clusters that both help, and hinder, development in ways not considered in present policy models.Read moreRead less
Special Research Initiatives - Grant ID: SR0354576
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. ....Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. Recognising these advances, this initiative focuses on harnessing Australia's capacity and potential in the use of spatially based methods and theories and brings researchers together in collaboration across a number of fields. Read moreRead less