Special Research Initiatives - Grant ID: SR0354576
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. ....Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. Recognising these advances, this initiative focuses on harnessing Australia's capacity and potential in the use of spatially based methods and theories and brings researchers together in collaboration across a number of fields. Read moreRead less
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
The Unique Nature Of Gamma Delta T Cell Recognition Resolved Through Interaction With H2-Q10
Funder
National Health and Medical Research Council
Funding Amount
$699,031.00
Summary
The liver is important for both digestion and immunity. Given these opposing functions, the liver must exert control points that prevent the immune system from recognising food products. We have now identified a new molecular target that controls the development of immune cells in the liver.
Disability and ability: how young people with impairments make the transition to adulthood. Compared to their able-bodied peers, 15-29 year olds with disabilities have an increased risk of negative social, physical and mental health outcomes. By analysing the life histories of 100 young people with physical impairments and tracking their development over four years, this project will explore how to reduce these risks.
Work, care, retirement and health: ageing agendas. This project will undertake a gendered analysis of how Australians can retire well, taking account of their key resources (such as work, superannuation, the aged pension, and other assets) and key demands (such as to work longer and to care for others in the context of an ageing population and a more feminised workforce).
Australia's Rural Heartlands: Declining Economic Fortune or Dynamic Regional Adjustment? Agriculture in the rural heartlands provides high quality food and fibre for domestic consumption and export making significant contributions to national earnings. The heartlands are the custodians of our natural resources and cultural heritage and farmers play a vital economic and social role in the sustainability of these regions. While there is considerable variability between these places this research ....Australia's Rural Heartlands: Declining Economic Fortune or Dynamic Regional Adjustment? Agriculture in the rural heartlands provides high quality food and fibre for domestic consumption and export making significant contributions to national earnings. The heartlands are the custodians of our natural resources and cultural heritage and farmers play a vital economic and social role in the sustainability of these regions. While there is considerable variability between these places this research will provide a detailed understanding as to why it is that rural places differ in their development. A major benefit will be to present Australian governments, the agricultural industry and rural communities with a more accurate picture of how the rural heartlands now function, and to articulate the public policy implications.Read moreRead less
Left Out and Missing Out: Towards New Indicators of Social Exclusion and Material Deprivation. This ground-breaking project will utilise academic knowledge and practical agency experience built up over decades to produce a new framework for identifying and measuring exclusion and deprivation in contemporary Australian society. It will generate new findings on public attitudes to the 'necessary requirements' needed to participate at all levels in society and the economy. It will examine the popul ....Left Out and Missing Out: Towards New Indicators of Social Exclusion and Material Deprivation. This ground-breaking project will utilise academic knowledge and practical agency experience built up over decades to produce a new framework for identifying and measuring exclusion and deprivation in contemporary Australian society. It will generate new findings on public attitudes to the 'necessary requirements' needed to participate at all levels in society and the economy. It will examine the population profile of the individuals and groups who are denied these opportunities, using both quantitative (survey) and qualitative (focus group) data, and its findings will complement existing data collections.Read moreRead less
Nuclear plasticity during neutrophil migration and function. This project aims to discover how nuclear shape affects neutrophil function. Cell migration needs overall cellular plasticity and plasticity of internal structures such as the nucleus. The neutrophil, one of the most peripatetic cell types, has a specialised lobulated nucleus, thought to facilitate its mobility and function. Using zebrafish reporter lines that concurrently display the nucleus and cytoplasm, this project will display th ....Nuclear plasticity during neutrophil migration and function. This project aims to discover how nuclear shape affects neutrophil function. Cell migration needs overall cellular plasticity and plasticity of internal structures such as the nucleus. The neutrophil, one of the most peripatetic cell types, has a specialised lobulated nucleus, thought to facilitate its mobility and function. Using zebrafish reporter lines that concurrently display the nucleus and cytoplasm, this project will display the dynamic plasticity of neutrophil nuclei during neutrophil migration and function in vivo. This project seeks to use the spatiotemporal resolution of a lattice light sheet microscope to examine this further, and explore its effect on neutrophil function. The project seeks to establish morphological and mechanical principles applying not just to neutrophils, but to all migratory cell types.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100056
Funder
Australian Research Council
Funding Amount
$190,000.00
Summary
An Australian Housing Condition Data Infrastructure. An Australian housing condition data infrastructure:
This project aims to develop, collect, and make available an Australian housing conditions data infrastructure. We don't know enough about the condition of Australia’s housing. In the nearly two decades since the last Australian Housing Survey, there have been significant changes in the housing system, and there researchers and policy makers are calling for a systematic, reliable and nation ....An Australian Housing Condition Data Infrastructure. An Australian housing condition data infrastructure:
This project aims to develop, collect, and make available an Australian housing conditions data infrastructure. We don't know enough about the condition of Australia’s housing. In the nearly two decades since the last Australian Housing Survey, there have been significant changes in the housing system, and there researchers and policy makers are calling for a systematic, reliable and nationally representative dataset of housing conditions. The infrastructure would provide Australia's a foundation for evidence-informed research on Australia's housing conditions. The data infrastructure would provide tools, data and protocols for Australian researchers and policy makers, and would be an accessible resource that can be built upon, adapted and applied to population groups and locations of interest.Read moreRead less
Elucidating the post-transcriptional regulation of mast cell proteases. Mast cells (MCs) are immune cells that protect against pathogens but may induce deleterious inflammation. MC function is mediated by specific proteases that are pre-formed and stored in granules. These proteases have unique yet poorly understood mechanisms of regulation. The aim of the project is to use a novel suite of molecular tools and genetically modified mice to identify the critical regions of transcripts that post-tr ....Elucidating the post-transcriptional regulation of mast cell proteases. Mast cells (MCs) are immune cells that protect against pathogens but may induce deleterious inflammation. MC function is mediated by specific proteases that are pre-formed and stored in granules. These proteases have unique yet poorly understood mechanisms of regulation. The aim of the project is to use a novel suite of molecular tools and genetically modified mice to identify the critical regions of transcripts that post-transcriptionally regulate the production and storage of these proteins. The project aims to identify the RNA binding proteins, microRNAs and other novel factors that also regulate them. This is expected to elucidate the post-transcriptional mechanisms of regulation of MC proteases.Read moreRead less