Discovery Indigenous Researchers Development - Grant ID: DI110100034
Funder
Australian Research Council
Funding Amount
$300,401.00
Summary
Measurement matters: analysis of potential methodological and discrimination biases in assessments of medication treatments for ADHD, and stakeholder views. This research aims to identify multiple stakeholders' views of the nature of Attention Deficit Hyperactivity Disorder and test if discrimination and survey wording result in bias when assessing the impact of medical treatments. This will result in understandings of discrimination and measurement bias; multiple stakeholders' perceptions; and ....Measurement matters: analysis of potential methodological and discrimination biases in assessments of medication treatments for ADHD, and stakeholder views. This research aims to identify multiple stakeholders' views of the nature of Attention Deficit Hyperactivity Disorder and test if discrimination and survey wording result in bias when assessing the impact of medical treatments. This will result in understandings of discrimination and measurement bias; multiple stakeholders' perceptions; and better methodology in research.
Read moreRead less
Arbovirus Activation And Modulation Of NLRP3 Inflammasome
Funder
National Health and Medical Research Council
Funding Amount
$779,720.00
Summary
This project aims to establish how mosquito borne viruses such as Ross River and dengue viruses interacts with the human host to cause disease, including how the virus evades the host’s immune response to persist and cause disease for prolonged periods. Knowing how differences in the virus and the host’s immune system interplay to cause asymptomatic to severely disabling disease will assist in devising new treatments and prevention programs to lessen the impact of these diseases in Australia.
Mosquito-borne alphaviruses such as Ross River and chikungunya viruses cause widespread epidemics and exert extreme pressure on the public health systems of affected regions. Alphaviruses spreads to joints and triggers a severe disease in those affected. There are no effective treatments or vaccines. The project will investigate virus-host interaction at the bite site. The outcome will be new knowledge to treat infection at the mosquito bite site to prevent joint disease.
Novel Insights Into The Pathobiology Of Alphavirus Infections
Funder
National Health and Medical Research Council
Funding Amount
$827,660.00
Summary
Infections with mosquito-borne viruses are increasing at an alarming rate worldwide. Ross River virus is endemic in parts of Australia, PNG and Pacific islands, while chikungunya virus is distributed globally and causes recurrent pandemics that involve millions of people. These viruses cause severe musculoskeletal disease for several months after infection. This project aims to establish how these viruses interact with the human host to cause disease and may provide a basis for new treatments.
Preventing Suicide: A psychological autopsy study of the last contact with a health professional before suicide. In Australia, 48% of all suicides in 2000 were by 35-64 year olds; an additional 13% were by 65 years and over. This study will examine the last clinical contact older suicide victims had with health professionals in order to determine whether this contact offers an opportunity for intervention. For the first time in Australia, GP's, health professionals, and the deceased's next-of-ki ....Preventing Suicide: A psychological autopsy study of the last contact with a health professional before suicide. In Australia, 48% of all suicides in 2000 were by 35-64 year olds; an additional 13% were by 65 years and over. This study will examine the last clinical contact older suicide victims had with health professionals in order to determine whether this contact offers an opportunity for intervention. For the first time in Australia, GP's, health professionals, and the deceased's next-of-kin will be interviewed to determine the context surrounding the deceased's death, and the abilities of health professionals to identify warning signs and to intervene prior to suicide. Given our ageing population, the outcomes will be significant in educating all health professionals to identify suicidal signs, and to prevent premature death in the elderly.Read moreRead less
Special Research Initiatives - Grant ID: SR0354531
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Social research network for sustainable rural communities. The triple bottom line of social, economic and environmental imperatives forms the accepted ingredients of sustainability. While the economic and environmental dimensions have been relatively well researched, there is insufficient understanding of the socio-cultural dimensions and how these determine environmental and health outcomes. The interactions between the dimensions are also poorly understood. While there are some researchers in ....Social research network for sustainable rural communities. The triple bottom line of social, economic and environmental imperatives forms the accepted ingredients of sustainability. While the economic and environmental dimensions have been relatively well researched, there is insufficient understanding of the socio-cultural dimensions and how these determine environmental and health outcomes. The interactions between the dimensions are also poorly understood. While there are some researchers in this field, they have tended to work in isolation. The development of a resourced interdisciplinary network to facilitate collaboration will increase the contribution and innovativeness of their collective research and contribute to understanding socio-economic determinants of dynamic regions and healthy rural communities.Read moreRead less
A longitudinal study into the development of personal vulnerabilities and well-being in adolescence. This longitudinal study examines the temperament and environmental factors that promote character strengths in adolescents. Character strengths such as empathy and emotion-management skills are potentially teachable and help prevent an adolescent from experiencing difficulties in social, emotional and academic adjustment.
Managing urban trees. Managing urban trees. This project aims to explore the effects of different urban tree types and plantings on people and wildlife in Melbourne, Moreland and Ballarat so they can better plan their future urban forests. Local governments spend millions of dollars planting and maintaining urban trees every year. Research provides little guidance to these land managers when making critical decisions in a rapidly changing social and physical environment. This project will combin ....Managing urban trees. Managing urban trees. This project aims to explore the effects of different urban tree types and plantings on people and wildlife in Melbourne, Moreland and Ballarat so they can better plan their future urban forests. Local governments spend millions of dollars planting and maintaining urban trees every year. Research provides little guidance to these land managers when making critical decisions in a rapidly changing social and physical environment. This project will combine tree inventory data with new information on the social and ecological effects of trees (e.g. human well-being, bird diversity). This research is expected to guide future tree management decisions that have better social and environmental outcomes for Australia’s cities.Read moreRead less
Investigating the role of the innate immune complement system in the abnormal development of the central nervous system. Past research has discovered a surprising link between the immune system, dietary folate deficiency and the development of the embryonic brain. This project will investigate the immune system in the developing brain, in order to understand the causes of developmental defects such as neural tube defects, and the role dietary folate plays in this process.
Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in ....Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in practice. It will generate data and validate a model on how to effectively improve the uptake of guidelines by both practitioners and consumers. This project is of national and community benefit because it will enable the potential of preventing chronic disease to be realised.Read moreRead less