Differences In Neonatal Immune Regulation In The Developing And Developed World: Implications For Neonatal Vaccinations?
Funder
National Health and Medical Research Council
Funding Amount
$332,083.00
Summary
This project will study the effect of adverse living conditions such as high microbial exposure, malnutrition, environmental tobacco smoke and malaria infection on the development of a newborn's immune system,by comparing immune response between newborns in Papua New Guinea and in Western Australia. This study will help us to understand the high susceptibility of children in the developing world for infectious diseases and to develop better prevention strategies.
Antiretroviral drugs reduce morbidity and mortality for people living with HIV however there is currently no cure for HIV. I will undertake a series of studies that will contribute to HIV cure research in Australia. This includes describing novel strategies to identify and measure residual dormant HIV in individuals on suppressive antiretroviral therapy, determining the effect of cancer drugs on dormant HIV, and exploring the attitudes of people living with HIV towards cure research.