Scalable Visual Analytics for Uncertain Dynamic Networks. Technological advances have provided a data deluge over the past few years, and have led to many large uncertain and dynamic network models. This includes terrorist networks, marketing networks, facebook networks, various biological networks, and software engineering structures. Human understanding of such networks is difficult. This project aims to provide new methods for visual analysis of large uncertain dynamic networks such as these. ....Scalable Visual Analytics for Uncertain Dynamic Networks. Technological advances have provided a data deluge over the past few years, and have led to many large uncertain and dynamic network models. This includes terrorist networks, marketing networks, facebook networks, various biological networks, and software engineering structures. Human understanding of such networks is difficult. This project aims to provide new methods for visual analysis of large uncertain dynamic networks such as these. The algorithms developed in the project will help security analysts to monitor illegal behaviour such as money laundering and terrorist activities, help biologists understand key biological systems, and help engineers to understand large software systems.Read moreRead less
Algorithms for geometric Turán-type problems and network visualization. Recent technological advances have large data sets, in a data deluge. Some of the most critical data sets are networks; examples abound in Systems Biology, Social Network Analysis, and Software Engineering. This project aims for algorithms to construct readable pictures of these networks, and thus make the data easier for humans to understand.
Discovery And Mechanisms Of Host Cell Factors In HIV Uncoating
Funder
National Health and Medical Research Council
Funding Amount
$635,098.00
Summary
HIV entry into the host cell involves release of its capsid, a protein shell protecting the viral genome. The capsid hijacks host proteins to cloak itself from cellular defenses while the cell has evolved sensors that can block viral infection. This proposal aims to discover proteins involved in this arms race between host and virus and decipher how they control capsid disassembly. This insight will help design new drugs against HIV infection and new ways to deliver genes for gene therapies.
Algorithmics for Interactive 2.5D Graph Drawing. Technological advances have provided a data deluge over the past few years, and consequently have led to many large and complex network models in many domains. This includes terrorrist networks and biological networks, software engineering structures, and webgraphs. Visualisation is an effective tool in helping humans to understand such networks. This project aims to provide a new direction in network visualisation, using 2.5 dimensions. The algor ....Algorithmics for Interactive 2.5D Graph Drawing. Technological advances have provided a data deluge over the past few years, and consequently have led to many large and complex network models in many domains. This includes terrorrist networks and biological networks, software engineering structures, and webgraphs. Visualisation is an effective tool in helping humans to understand such networks. This project aims to provide a new direction in network visualisation, using 2.5 dimensions. The algorithms developed in the project will help security analysts to detect abnormal behavious such as money laundering, help biologists understand protein-protein interaction networks, and help engineers to understand large software systems.Read moreRead less
Efficient and Effective Interactive Visualization of Large Graphical Information Spaces. The expected outcome will change ways of interacting with and thinking about information processing for all information systems. As Australian companies became larger and more global, the ability to view and analyse the growing amount of company information becomes crucial to aspects as varied as trouble shooting or new ventures and eventually to the very viability of the organization itself. The expected ou ....Efficient and Effective Interactive Visualization of Large Graphical Information Spaces. The expected outcome will change ways of interacting with and thinking about information processing for all information systems. As Australian companies became larger and more global, the ability to view and analyse the growing amount of company information becomes crucial to aspects as varied as trouble shooting or new ventures and eventually to the very viability of the organization itself. The expected outcome will enhance this ability by providing an optimised global view and an effective navigation scheme of large graphical information spaces. This will attract leading international IT companies to use it for developing cutting-age tools, and will enhance significantly the capacity and international standing of Australian IT industry.Read moreRead less
An Integrative and Interactive Approach for Co-estimation of Multiple Sequence Alignment and Phylogeny Reconstruction. In this project innovative IT methods will be developed to assist biologists to solve complex and important biological problems. Many important applications in computational biology need very accurate and reliable tools for multiple sequence alignment and phylogeny reconstruction. Unfortunately, current existing tools are unreliable and are prone to serious errors when applied t ....An Integrative and Interactive Approach for Co-estimation of Multiple Sequence Alignment and Phylogeny Reconstruction. In this project innovative IT methods will be developed to assist biologists to solve complex and important biological problems. Many important applications in computational biology need very accurate and reliable tools for multiple sequence alignment and phylogeny reconstruction. Unfortunately, current existing tools are unreliable and are prone to serious errors when applied to large and divergent biological sequences. The success of this project will not only make significant contribution to the relevant research fields, but also help achieve goals in certain real-life biological research projects which are unique and important to Australia.Read moreRead less
Visual analytics for massive multivariate networks. Visual analytics for massive multivariate networks. This project aims to create methods to visually analyse massive multivariate networks. The amount of network data available has exploded in recent years: software systems, social networks and biological systems have millions of nodes and billions of edges with multivariate attributes. Their size and complexity makes these data sets hard to exploit. More efficient ways to understand the data ar ....Visual analytics for massive multivariate networks. Visual analytics for massive multivariate networks. This project aims to create methods to visually analyse massive multivariate networks. The amount of network data available has exploded in recent years: software systems, social networks and biological systems have millions of nodes and billions of edges with multivariate attributes. Their size and complexity makes these data sets hard to exploit. More efficient ways to understand the data are needed. This project will design, implement and evaluate visualisation methods for massive multivariate network data sets. This research is expected to be used by Australian software development, biotechnology and security companies to exploit their data.Read moreRead less
Inhibition Of Cellcell Actin-based Motility During Poxvirus Infection By The Kinase Inhibitor Glivec
Funder
National Health and Medical Research Council
Funding Amount
$92,950.00
Summary
Although smallpox, one of the deadliest human pathogens, was eradicated in 1980, the current global climate has resulted in fears that smallpox may be used as a biological weapon. Unfortunately the smallpox vaccine poses a serious health hazard to certain people. We have shown that Glivec, a drug used to treat cancer, has potent anti-viral affects on poxvirus replication. This project will test the effectiveness of Glivec in treating smallpox in an animal model and study how it acts.
Visual analytics for high volume multi attribute financial data streams. While our ability to accumulate data (such as financial data) is increasing, our capability to analyse them is still inadequate despite technological improvements. The new Visual Analytics methods will allow processing of the massive and time-varying data so that the time-critical decisions can be made with minimum effort.