An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internatio ....Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internationalisation strategies and consumption of Chinese culture on digital platforms in China, Australia, Hong Kong, Singapore and South Korea. It expects to understand the implications of China's digital ascendency and the lessons for Australia in the post-resources boom era.Read moreRead less
Hydrogen generation by subsurface iron mineral transformations. Aim
The aim of this project is to elucidate key factors responsible for natural hydrogen generation in Australian subsurface environments.
Significance
Large amounts of this valuable resource are produced naturally with estimates of production rates of this “gold” hydrogen at least 100 times the annual demand for this critical resource.
Expected Outcomes
Based on improved understanding of the source of natural hydrogen, predictive ....Hydrogen generation by subsurface iron mineral transformations. Aim
The aim of this project is to elucidate key factors responsible for natural hydrogen generation in Australian subsurface environments.
Significance
Large amounts of this valuable resource are produced naturally with estimates of production rates of this “gold” hydrogen at least 100 times the annual demand for this critical resource.
Expected Outcomes
Based on improved understanding of the source of natural hydrogen, predictive tools will be developed that will assist in assessing the viability in Australia of hydrogen exploration and engineered retrieval.
Benefits
Ready access to naturally produced hydrogen could enable Australia to replace hydrogen that is currently generated via the use of unabated hydrocarbons.Read moreRead less
Pushing AR Toward Better Outcomes In Breast And Prostate Cancers
Funder
National Health and Medical Research Council
Funding Amount
$998,754.00
Summary
Breast and prostate cancers kill >6000 Australians each year. These cancers are strikingly similar, both driven by hormone receptors that have ‘gone bad’. Current therapies aim to eradicate the receptors. While often effective, therapeutic resistance is common and results in fatal disease. We aim to develop new, less toxic treatments that switch receptor behaviour from good to bad, without destroying them. This should improve quality of life, while preventing drug resistance and loss of lives ....Breast and prostate cancers kill >6000 Australians each year. These cancers are strikingly similar, both driven by hormone receptors that have ‘gone bad’. Current therapies aim to eradicate the receptors. While often effective, therapeutic resistance is common and results in fatal disease. We aim to develop new, less toxic treatments that switch receptor behaviour from good to bad, without destroying them. This should improve quality of life, while preventing drug resistance and loss of lives.Read moreRead less
A Randomised Controlled Trial (RCT) Of Azithromycin Versus Doxycycline For The Treatment Of Rectal Chlamydia Infection In Men Who Have Sex With Men.
Funder
National Health and Medical Research Council
Funding Amount
$797,906.00
Summary
Rectal chlamydia is very common among gay men; it can exist for long periods without symptoms leading to ongoing transmission. Azithromycin (1 gram single dose) or 7 days doxycycline (100mg twice daily) are the two recommended treatments globally. But, there is concern about rectal chlamydia treatment with reports of up to 22% failure following azithromycin. We will conduct a randomised trial to compare these treatments for rectal chlamydia and determine which drug works better.
Discovery Early Career Researcher Award - Grant ID: DE180100950
Funder
Australian Research Council
Funding Amount
$368,446.00
Summary
Building intelligence into online video services by learning user interests. This project aims to build an intelligent video streaming service by characterising users’ view interest patterns and predict user interest changes through learning data from Internet to address the challenge caused by astronomic video population. The outcomes of the project will be of great values for users and our society by intelligently filtering out valueless, harmful, illegal and unwanted videos in advance.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100127
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Controlled radiation facility to investigate turbulence-radiation-chemistry interactions in high-flux solar reactors. This project's facility will support the transition of Australia’s energy intensive industries, including minerals and resources, to a much lower carbon intensity. It will also underpin collaborations with internationally leading partners to develop novel solar-combustion hybrid reactors for the production of solar fuels and for minerals processing.
Switching Dynamics Approach for Distributed Global Optimisation . This project aims to create a breakthrough switching dynamics approach and new technology to speed up finding optimal solutions. It will develop a distributed switching dynamics based optimisation scheme for global optimisation problems in industrial big-data environments where timely decision making is required. It will result in a practical technology for industry optimisation problems such as economic energy dispatch in smart g ....Switching Dynamics Approach for Distributed Global Optimisation . This project aims to create a breakthrough switching dynamics approach and new technology to speed up finding optimal solutions. It will develop a distributed switching dynamics based optimisation scheme for global optimisation problems in industrial big-data environments where timely decision making is required. It will result in a practical technology for industry optimisation problems such as economic energy dispatch in smart grids and optimal charging and discharging tasks in a large network of electric vehicles, helping Australian power industry improve efficiency and security, as well as training the next generation scientists and engineers for Australia in this emerging field.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100119
Funder
Australian Research Council
Funding Amount
$427,111.00
Summary
Towards Internet of Things Enabled Automated Mushroom Cultivation. This project aims to develop novel Internet-of-Things based learning techniques to inform the design and construction of a portable, automated system for the cultivation of mushrooms. The expected outcomes are a portable smart mushroom cultivation system that provides access to new agriculture techniques and local, fresh supplies in rural and remote areas; learning algorithms that detect mushroom ripeness and set the best environ ....Towards Internet of Things Enabled Automated Mushroom Cultivation. This project aims to develop novel Internet-of-Things based learning techniques to inform the design and construction of a portable, automated system for the cultivation of mushrooms. The expected outcomes are a portable smart mushroom cultivation system that provides access to new agriculture techniques and local, fresh supplies in rural and remote areas; learning algorithms that detect mushroom ripeness and set the best environmental parameters; and a dataset of mushroom cultivation parameters. These products, and associated training opportunities through a strong focus on public and industry engagement, will benefit the industry partners and horticultural producers to improve resource efficiency, waste reduction, and overall yield.Read moreRead less
Virtual Galleries: new media technologies to influence livelihood and arts participation in remote communities of the Northern Territory, Australia. The Virtual Galleries project addresses the issue of limited economic development in remote communities by introducing a user-controlled webcam and interactive 3-D (three-dimensional) Art Galleries into remote art centres to help people in remote communities to secure an income and create wealth and social wellbeing for themselves, their families an ....Virtual Galleries: new media technologies to influence livelihood and arts participation in remote communities of the Northern Territory, Australia. The Virtual Galleries project addresses the issue of limited economic development in remote communities by introducing a user-controlled webcam and interactive 3-D (three-dimensional) Art Galleries into remote art centres to help people in remote communities to secure an income and create wealth and social wellbeing for themselves, their families and their communities.Read moreRead less