Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internatio ....Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internationalisation strategies and consumption of Chinese culture on digital platforms in China, Australia, Hong Kong, Singapore and South Korea. It expects to understand the implications of China's digital ascendency and the lessons for Australia in the post-resources boom era.Read moreRead less
Revolutionising The Diagnosis And Monitoring Of CF Lung Disease
Funder
National Health and Medical Research Council
Funding Amount
$818,391.00
Summary
Cystic fibrosis (CF) lung disease starts early in childhood and relentlessly progresses, with early death a common outcome. There is currently no method capable of detecting very early disease onset nor directly assessing the effectiveness of putative treatments. This project will apply our globally unique X-ray imaging tools, which are capable of imaging lung function at any point across the entire lung, for the very early detection of CF and assessment of clinically applicable treatments.
Innovation In The Synthesis And Translation Of Research Evidence To Inform The Prevention, Management And Treatment Of Chronic Disease In Indigenous Populations
Funder
National Health and Medical Research Council
Funding Amount
$2,642,121.00
Summary
Chronic disease remains the principal cause of health inequality for Indigenous Australians. Primary care is critical to mounting a health system response. The Aboriginal community controlled sector is at the coal face of chronic disease management, yet requires the synthesis, utilisation, development, evaluation and translation of evidence to practice. CREATE was established for this purpose
Switching Dynamics Approach for Distributed Global Optimisation . This project aims to create a breakthrough switching dynamics approach and new technology to speed up finding optimal solutions. It will develop a distributed switching dynamics based optimisation scheme for global optimisation problems in industrial big-data environments where timely decision making is required. It will result in a practical technology for industry optimisation problems such as economic energy dispatch in smart g ....Switching Dynamics Approach for Distributed Global Optimisation . This project aims to create a breakthrough switching dynamics approach and new technology to speed up finding optimal solutions. It will develop a distributed switching dynamics based optimisation scheme for global optimisation problems in industrial big-data environments where timely decision making is required. It will result in a practical technology for industry optimisation problems such as economic energy dispatch in smart grids and optimal charging and discharging tasks in a large network of electric vehicles, helping Australian power industry improve efficiency and security, as well as training the next generation scientists and engineers for Australia in this emerging field.Read moreRead less
Hydrogen carbon waste into concrete: AI assisted nanoscience approach. The carbon waste from hydrogen production will be converted into carbon nanosheets on abundant construction materials for the creation of stronger and more durable concrete. Cutting-edge nanoscience-based experiments, as well as sophisticated modelling techniques including machine learning and finite element modelling, will be employed. The findings will drive advances in clean hydrogen production, carbon waste utilisation, c ....Hydrogen carbon waste into concrete: AI assisted nanoscience approach. The carbon waste from hydrogen production will be converted into carbon nanosheets on abundant construction materials for the creation of stronger and more durable concrete. Cutting-edge nanoscience-based experiments, as well as sophisticated modelling techniques including machine learning and finite element modelling, will be employed. The findings will drive advances in clean hydrogen production, carbon waste utilisation, cement hydration, nanotechnology and concrete technology for the next generation of an upskilled workforce and the promotion of a circular economy. This project will be carried out in collaboration with Australian and international renowned experts in computational modelling, nanomaterials and concrete materials.Read moreRead less
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
How does timing affect mammalian brain development and evolution? This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understandi ....How does timing affect mammalian brain development and evolution? This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understanding the dynamics of developmental systems that shape complex brain traits includes establishing new developmental paradigms in evolutionary theory, generating new tools to investigate and manipulate brain gene expression in vivo, and the potential discovery of the causes of neurodevelopmental dysfunction.Read moreRead less
Synchrotron X-ray Assessment Of Airway Surface Physiology For Cystic Fibrosis
Funder
National Health and Medical Research Council
Funding Amount
$778,228.00
Summary
We seek a cure or long-lasting therapy for the fatal airway disease in cystic fibrosis. Disease is caused by a shallow and dehydrated airway surface liquid (ASL), allowing bacteria to infect the lung. We can introduce a corrective gene into mouse airways where it can be effective for over 1 yr, but no fast, accurate and non-invasive measurement exists to test if treatments are successful. We will develop methods using synchrotron light to directly measure ASL depth changes in live mouse airways.
The genetic regulation of organogenesis: endoderm development in the Drosophila embryo. Embryonic development is an important research field in biology, not only for its extraordinary complexity but also because of the insights it provides into molecular processes that underpin a variety of diseases. This project aims to discover genes and molecules that regulate the normal development of one of the most important organs, the gut.