The structure and function of the human spinal connectome. This project will use complex network analysis to map the interactions between the brain and body, to understand how the central nervous system controls our movements. The project will provide fundamental insights into mechanisms that coordinate activity in the human motor system, and how the breakdown of coordination may lead to movement disorders. By integrating advanced computational analyses with state-of-the-art recording techniques ....The structure and function of the human spinal connectome. This project will use complex network analysis to map the interactions between the brain and body, to understand how the central nervous system controls our movements. The project will provide fundamental insights into mechanisms that coordinate activity in the human motor system, and how the breakdown of coordination may lead to movement disorders. By integrating advanced computational analyses with state-of-the-art recording techniques, the project will generate new knowledge of the neural basis of human motor coordination. Expected outcomes may support future applications to restore motor function through brain stimulation, prosthetics and robotics design.Read moreRead less
A history of Australia's 1998 waterfront dispute. The project will produce an innovative account of Australia's Easter 1998 waterfront dispute, within the context of a wider body of research on diverse but related social perspectives. The aim is to not only enhance understanding of the event, but to employ the event to enhance understanding of social relations. The project is based on the hypothesis that the social memory is more complex, multi-layered and contextual than public accounts suggest ....A history of Australia's 1998 waterfront dispute. The project will produce an innovative account of Australia's Easter 1998 waterfront dispute, within the context of a wider body of research on diverse but related social perspectives. The aim is to not only enhance understanding of the event, but to employ the event to enhance understanding of social relations. The project is based on the hypothesis that the social memory is more complex, multi-layered and contextual than public accounts suggest. By incorporating the study of multiple perspectives, the aim is to disclose a different and more insightful memory of both the event and the society in which it occurred.Read moreRead less
A New Clinical Tool To Assess Fitness-to-drive In Obstructive Sleep Apnea
Funder
National Health and Medical Research Council
Funding Amount
$727,963.00
Summary
Obstructive sleep apnoea (OSA) affects 1 in 4 middle aged adults. OSA results in impaired neurobehavioral function, excessive sleepiness, and more than 2-fold increased motor vehicle crash risk and workplace accidents. However, not all patients are impaired and identifying patients at risk is a daily clinical challenge. This project proposes new and simple measures that can accurately identify patients with OSA who are most vulnerable to alertness failure and motor vehicle accident risk.
Motor problems, ranging from clumsiness to cerebral palsy, are one of the most common adverse outcomes in children born early. This study will investigate the motor development of children born <30 weeks’ gestation compared with peers born at term from birth to 5 years. We will determine whether early clinical evaluations or neuroimaging in the newborn period can predict later motor impairment at 5 years to be able to identify those who will benefit most from early intervention.
From rivers of gold to the clickstream: Newspapers and quality journalism in the Internet Age. This project will enhance Australian democracy by providing a scholarly basis for public discussion about the ways that quality journalism can survive in the Internet age. It will create knowledge about the specifically Australian experience of newspapers' transition to online media services and will thus help Australian citizens and journalists engage in global debates about journalism futures. It wil ....From rivers of gold to the clickstream: Newspapers and quality journalism in the Internet Age. This project will enhance Australian democracy by providing a scholarly basis for public discussion about the ways that quality journalism can survive in the Internet age. It will create knowledge about the specifically Australian experience of newspapers' transition to online media services and will thus help Australian citizens and journalists engage in global debates about journalism futures. It will create knowledge about the workplace conditions that foster quality journalism. It will showcase Australian research in international scholarly debate within the field of Journalism Studies.Read moreRead less
BRAIN-MEND: Biological Resource Analysis To Identify New Mechanisms And Phenotypes In Neurodegenerative Diseases
Funder
National Health and Medical Research Council
Funding Amount
$861,866.00
Summary
Current classification of neurodegenerative diseases (ND) based on clinical phenotypes does not take into account underlying disease heterogeneity, or overlapping disease mechanisms, thus hindering therapy development. Segregation and re-classification of ND phenotypes is urgently needed. BRAIN-MEND will reclassify existing phenotypic classifications using using pathway and network analyses within and across complex NDs.
Frontotemporal Dementia And Motor Neurodegenerative Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$11,583,107.00
Summary
Frontotemporal degeneration of the brain is a leading cause of morbidity. It is a pathologically heterogeneous group of rapidly-progressive disorders with behavioural, language and motor deficits. This research program brings together international leaders in clinical, pathological and biological research of these syndromes, aiming to fast track new knowledge and innovations to develop the necessary tools and therapies to effectively diagnose, manage and treat these disorders.
An Examination Of Motor Functioning In Autism And Asperger's Disorder: An Analysis Of Gait & Cortical Brain Activity.
Funder
National Health and Medical Research Council
Funding Amount
$120,220.00
Summary
Autism is a developmental disorder characterised by a triad of deficits: delayed and atypical language development, impaired development of social skills, and ritualistic and stereotypic behaviour. Although not part of the standard diagnosis, movement disorders and gait abnormalities have been clinically observed in autism similar to those seen in Parkinson's disease. In addition, individuals with Asperger's disorder may appear more clumsy, have a stiff or awkward way of walking, and exhibit poo ....Autism is a developmental disorder characterised by a triad of deficits: delayed and atypical language development, impaired development of social skills, and ritualistic and stereotypic behaviour. Although not part of the standard diagnosis, movement disorders and gait abnormalities have been clinically observed in autism similar to those seen in Parkinson's disease. In addition, individuals with Asperger's disorder may appear more clumsy, have a stiff or awkward way of walking, and exhibit poor coordination in posture and gesture. It has been suggested that there is disruption within the basal-ganglia-thalamocortical circuitry (the region connecting the frontal and sub-cortical structures), which may cause the motor dysfunction seen in autism and Asperger's disorder. Few studies have attempted to isolate particular stages of motor functioning which may account for the coordination and motor delay observed clinically in autism and Asperger's disorder. A recent study of ours found evidence to suggest that motor planning deficiencies may account for the 'clumsy' movement patterns frequently reported in the autism - Asperger's disorder literature. Therefore, the aim of this research is to provide a comprehensive neurobehavioural and neurophysiological analysis of motor functioning in young people with autism and Asperger's disorder to further examine the exact stages of motor processing which are deficient in these disorder groups. Recent retrospective studies have shown that even as infants children with autism exhibit clear features of motor disturbance, which, if detected and clearly defined, could advance early diagnosis. In addition to advancing the clinical definition of autism and Asperger's disorder, a careful examination of motor disturbance may also illuminate the neurobiological underpinnings of these disorders.Read moreRead less
The Impact Of Globalisation On Employment Relations: A Comparison Of The Auto And Banking Industries In Australia And Korea. The project compares the impact of globalisation on employment relations in Australia and South Korea by analysing changes in the auto and banking industries since the mid 1990s. It is expected that the interactions between economic factors, institutional arrangements and strategic decision making will have led to both continuity and change in employment relations during t ....The Impact Of Globalisation On Employment Relations: A Comparison Of The Auto And Banking Industries In Australia And Korea. The project compares the impact of globalisation on employment relations in Australia and South Korea by analysing changes in the auto and banking industries since the mid 1990s. It is expected that the interactions between economic factors, institutional arrangements and strategic decision making will have led to both continuity and change in employment relations during this period. The study will introduce a new theoretical dimension to comparative industrial relations by testing an ?interaction? approach. It will also provide a deeper understanding of the reasons for similarities and differences between employment relations in Australia and South Korea and indicate likely future developments.Read moreRead less
Enforcing labour standards in supply chains through voluntary frameworks. This project aims to investigate the potential of multi-stakeholder initiatives to ensure the enforcement of labour standards in supply chains by examining the cleaning accountability framework - an initiative comprised of diverse representatives in the commercial cleaning supply chain in Australia. It is expected that this will result in the development of new regulatory methods/technology to improve compliance. This is e ....Enforcing labour standards in supply chains through voluntary frameworks. This project aims to investigate the potential of multi-stakeholder initiatives to ensure the enforcement of labour standards in supply chains by examining the cleaning accountability framework - an initiative comprised of diverse representatives in the commercial cleaning supply chain in Australia. It is expected that this will result in the development of new regulatory methods/technology to improve compliance. This is expected to improve the quality of life of vulnerable workers in supply chains and the mitigation of reputational risk for business.
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