Evolution And Function Of A Novel Lateral Flagellar Locus, Flag-2, In Pathogenic Escherichia Coli
Funder
National Health and Medical Research Council
Funding Amount
$465,158.00
Summary
This project will study how the bacteria that cause infant diarrhoea colonize the intestine and induce disease. We have identified a novel genetic region that allows E. coli to survive and persist in the intestine. Similar genes are also present in closely related organisms. This project will help us to undestand how new diseases evolve and emerge and may lead to the development of new vaccines to protect against infant diarrhoea.
Harnessing Neuroplasticity To Improve Motor Performance In Infants With Cerebral Palsy: A Pragmatic Randomized Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,736,349.00
Summary
Every 15 hours an Australian baby is born with cerebral palsy. Despite confidence in early intervention, 50% don't receive intervention before their first birthday while awaiting diagnosis, and 8 of 10 previous trials have not produced any physical gains over and above natural development. We have promising data about a new brain training intervention that harnesses neuroplasticity and improves movement. Our trial will treat 300 infants with early training comparing results to Standard Care.
Musculoskeletal injuries sustained as a consequence of road traffic crashes are common and costly to the Australian community. Many people do not recover well after the injury but suffer ongoing pain and disability. The Centre for Research Excellence in Recovery Following Road Traffic Injury will target a clear need to improve health outcomes for injured individuals through research, capacity building and end-user engagement with a focus in primary care.
Re-inventing Motherhood: Women, Breadwinning and Childcare in Australia, 1880-1980. The project aims to analyse the evolving experiences of working mothers in Australia from 1880 to 1980 to ascertain how women and their families handled the tensions between work, survival strategies, and child care. It will challenge current views of a simple dichotomy between public work and private family lives, exploring the interlinking of forms of work and care, and their intersections with class, ethnicity ....Re-inventing Motherhood: Women, Breadwinning and Childcare in Australia, 1880-1980. The project aims to analyse the evolving experiences of working mothers in Australia from 1880 to 1980 to ascertain how women and their families handled the tensions between work, survival strategies, and child care. It will challenge current views of a simple dichotomy between public work and private family lives, exploring the interlinking of forms of work and care, and their intersections with class, ethnicity and race.This will provide a significant new base for understanding the historical evolution of women's work and family life and for formulating social policy today in an age of the dual-income family.Read moreRead less
It’s The Amount That Counts: The Impact Of Seven Days Of Sleep Restriction On Predictors Of Type 2 Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$743,269.00
Summary
The aim of this project is to examine the relationship between sleep duration (5, 6, 7, 8, or 9h per day for one week) and glucose metabolism. This will allow us to quantify the amount of harm that different levels of sleep loss cause to the physiological systems that protect people from developing serious health disorders. In particular, the results of the project will be invaluable in the design of effective behavioural interventions for the prevention and/or treatment of type 2 diabetes.
Sleep Health And Sleep Problems In Early Childhood: What Role Does Childcare Play?
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Sleep is significant for young children’s health and development and impacts on family functioning. Increasingly childcare is part of the young child’s sleep environment. This study focuses on the role of childcare in supporting sleep health and identifying sleep, and associated behavioural problems, in the early years of life. The study responds to the policy, practice and legislative demand for evidence to guide appropriate provision for sleep and rest in the childcare context.
Responding to the rural skills crisis: Modelling volunteer motivations and incentives to attract retired/semi-retired professionals to volunteer in rural areas. This project contributes directly to Promoting and Maintaining Good Health: Ageing well, ageing productively by placing a high value on the skills of older Australians and encouraging them to remain productive into retirement by sharing these skills. This project will also strengthen the social and economic fabric of rural communities by ....Responding to the rural skills crisis: Modelling volunteer motivations and incentives to attract retired/semi-retired professionals to volunteer in rural areas. This project contributes directly to Promoting and Maintaining Good Health: Ageing well, ageing productively by placing a high value on the skills of older Australians and encouraging them to remain productive into retirement by sharing these skills. This project will also strengthen the social and economic fabric of rural communities by addressing the identified national priority area of skills shortages in rural areas by providing rural councils with a means to access skilled professionals to assist them in enhancing their economic and social sustainability. Further, use of sound, well-tested psychological theories of individual decision making will enhance the validity and applicability of the model.Read moreRead less
Home-based Businesses: Belief systems and practice and their implications for policy and development practice. The home-based business sector has been calculated to represent 67% of the small business sector in Australia. There is a conservative estimate that at least one in ten homes in Australia now hosts a home-based business. Under Governments of all political persuasions, growth of small business is seen as important to the growth of the economy. However there is a fragmented policy context ....Home-based Businesses: Belief systems and practice and their implications for policy and development practice. The home-based business sector has been calculated to represent 67% of the small business sector in Australia. There is a conservative estimate that at least one in ten homes in Australia now hosts a home-based business. Under Governments of all political persuasions, growth of small business is seen as important to the growth of the economy. However there is a fragmented policy context of enterprise promotion and home-based business support. The findings of this study will contribute to integrated policy and development practice responses through greater understanding of the diversity of belief systems and practice within the sector.Read moreRead less
Gender and Employment Equity: Strategies for Advancement in Australian Universities. Gender inequity in pay and employment remain a feature of Australian society and can impair labour productivity. Lower female labour force participation rates continue to be a major issue, resulting in less than optimum use of women's skills. This project undertakes detailed analysis of these issues in Australian Universities, the major training site for the national skilled workforce. It will develop practical ....Gender and Employment Equity: Strategies for Advancement in Australian Universities. Gender inequity in pay and employment remain a feature of Australian society and can impair labour productivity. Lower female labour force participation rates continue to be a major issue, resulting in less than optimum use of women's skills. This project undertakes detailed analysis of these issues in Australian Universities, the major training site for the national skilled workforce. It will develop practical strategies to promote gender equity in universities. As women's participation is a major driver of labour force growth, this research will provide vital information for many industries.Read moreRead less
Urinary continence and incontinence in men: New insight through new technologies. Healthy ageing in men is largely overlooked. Disorders of continence are surprisingly common with increasing age, and are socially debilitating. To understand changes in continence and address healthy ageing it is first necessary to gain an understanding of continence mechanisms in healthy men. Continence in women has received wide attention, but anatomy and function differ, as do the challenges throughout life (ch ....Urinary continence and incontinence in men: New insight through new technologies. Healthy ageing in men is largely overlooked. Disorders of continence are surprisingly common with increasing age, and are socially debilitating. To understand changes in continence and address healthy ageing it is first necessary to gain an understanding of continence mechanisms in healthy men. Continence in women has received wide attention, but anatomy and function differ, as do the challenges throughout life (childbirth vs. prostate disease). Using novel methods we will test a new hypothesis of male continence with the goal to provide new physiological discoveries, new methods, and baseline data upon which strategies to enhance healthy ageing and reduce the economic burden of disorders of continence can be developed and refined. Read moreRead less