Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100168
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Facility for Characterisation of BioNanomaterials. Facility for characterisation of bionanomaterials:
The facility for characterisation of bionanomaterials aims to provide researchers with access to an integrated facility for advanced characterisation of nanomaterials from inception to application in biomedicine. Nanotechnology has contributed to significant advances across a range of disciplines and is increasingly used in biomedical applications. The facility aims to allow detailed examinatio ....Facility for Characterisation of BioNanomaterials. Facility for characterisation of bionanomaterials:
The facility for characterisation of bionanomaterials aims to provide researchers with access to an integrated facility for advanced characterisation of nanomaterials from inception to application in biomedicine. Nanotechnology has contributed to significant advances across a range of disciplines and is increasingly used in biomedical applications. The facility aims to allow detailed examination of how nanomaterials interact in biological systems; from individual nanoparticles to whole animals, and through developing this fundamental understanding provide the means to produce new and highly effective nanomaterials for biomedical applications. The facility plans to support programs using nanomaterials for molecular imaging and intelligent drug delivery, while developing greater understanding of how to create more effective nanobiomaterials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100156
Funder
Australian Research Council
Funding Amount
$289,500.00
Summary
3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-ti ....3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-tissue interfaces), biomedical devices (implantable devices and drug-delivery systems), nanofluidics, and photonic crystals. In each of these fields, we will use GT2 to print variety of polymers, hydrogels, metals and ceramics, for example by printing polymer-derived nanoceramics that will be simultaneously strong and tough.Read moreRead less
Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less
Trapping and Watching Biomolecular Complexes near Nanopores. This project aims to develop a technology to trap and interrogate nanosized molecular complexes in their natural state. Nanosized complexes in water provide the core machinery of biological systems and require detailed understanding to help unravel fundamental biological mechanisms. A prototype of a methodology has been developed to trap and interrogate nanoscaled objects as small as 190 nanometres within a nanopore device. By performi ....Trapping and Watching Biomolecular Complexes near Nanopores. This project aims to develop a technology to trap and interrogate nanosized molecular complexes in their natural state. Nanosized complexes in water provide the core machinery of biological systems and require detailed understanding to help unravel fundamental biological mechanisms. A prototype of a methodology has been developed to trap and interrogate nanoscaled objects as small as 190 nanometres within a nanopore device. By performing research to fully understand, miniaturise and develop this method further, this project aims to enable the quantitative observation of nanoscaled biological machinery involved in cell-to-cell communication and DNA unfolding. Such a technology platform may have applications in areas such as biology, biotechnology and advanced materials.Read moreRead less
Pressure waves on the mechanics of earthquakes and faulting. This project aims to decipher the physics of faulting and earthquakes from damage zones around seismogenic faults. It will examine a mechanism for instability in solids: volumetric collapse due to a dissipative pressure wave. This pressure wave may control damage-zone geometry and relate to earthquake stress and rock material properties. The project will research the instability through theoretical, laboratory and field studies. Antici ....Pressure waves on the mechanics of earthquakes and faulting. This project aims to decipher the physics of faulting and earthquakes from damage zones around seismogenic faults. It will examine a mechanism for instability in solids: volumetric collapse due to a dissipative pressure wave. This pressure wave may control damage-zone geometry and relate to earthquake stress and rock material properties. The project will research the instability through theoretical, laboratory and field studies. Anticipated outcomes include advances in earthquake and fault prediction, tools to determine the stress state and material properties of Earth’s crust, and knowledge of a class of solid instabilities.Read moreRead less
ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, eng ....ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, engineers and physicists, allowing us to translate our discoveries into novel technologies for the social and economic benefit of all Australians. We will also train a new generation of multidisciplinary researchers, and contribute our expertise to a range of public education and awareness programs.Read moreRead less
Random network models with applications in biology. Complex biological systems consist of a large number of interacting agents or components, and so can be studied using mathematical random network models. We aim to gain deeper insights into the laws emerging as the random networks evolve in time. This can help us to deal with dangerous disease epidemics and better understand the human brain.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100127
Funder
Australian Research Council
Funding Amount
$355,000.00
Summary
Superresolution fluorescence imaging in microbiology. Superresolution fluorescence imaging in microbiology:
This project involves the purchase of new, and upgrade of existing, fluorescence imaging tools to facilitate the study of intracellular processes in microbial systems at significantly higher spatial and temporal resolutions than hitherto possible. Visualisation of the structure and dynamics of intracellular molecular assemblies at maximal resolution is required to understand protein funct ....Superresolution fluorescence imaging in microbiology. Superresolution fluorescence imaging in microbiology:
This project involves the purchase of new, and upgrade of existing, fluorescence imaging tools to facilitate the study of intracellular processes in microbial systems at significantly higher spatial and temporal resolutions than hitherto possible. Visualisation of the structure and dynamics of intracellular molecular assemblies at maximal resolution is required to understand protein function inside living cells. The new equipment is designed to provide a fast super-resolution imaging system to study the intracellular dynamics of proteins in vitro and a super-resolution microscope to visualise structures and assemblies inside microbes with a resolution of tens of nanometres, putting in vitro biochemistry into the context of a living cell. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101073
Funder
Australian Research Council
Funding Amount
$355,000.00
Summary
Defying conventions with a liquid metal-embedded hybrid elastomer composite. Conductive elastic composites are one of the key components used in flexible/wearable electronic devices in the manufacture of sensors and interconnects; however, conventional composites experience a relatively low sensitivity to strain, and their conductivity decreases when stretched (i.e. they exhibit a negative piezoconductive effect). This project aims to understand the unprecedented positive piezoconductive effect ....Defying conventions with a liquid metal-embedded hybrid elastomer composite. Conductive elastic composites are one of the key components used in flexible/wearable electronic devices in the manufacture of sensors and interconnects; however, conventional composites experience a relatively low sensitivity to strain, and their conductivity decreases when stretched (i.e. they exhibit a negative piezoconductive effect). This project aims to understand the unprecedented positive piezoconductive effect exhibited on the liquid metal-embedded hybrid elastomer (LMHE) and explore its potential to address the key challenges faced by conventional materials. The outcomes of this project will benefit the advanced manufacturing sector by developing high-performance composites to revolutionise future wearable electronic technologies.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.