Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
Talent Mismatch: Evidence from Australian Administrative Tax Records. The project aims to study the skill composition of the Australian workforce. Changes in the macroeconomic and technology environments make it hard to predict skill shortage. The project expects to develop macroeconomic models quantifying skill-mismatch of university graduates, identify sources of mismatch, highlight gender and generational differences, and estimate associated costs to Australia. The expected outcomes are to he ....Talent Mismatch: Evidence from Australian Administrative Tax Records. The project aims to study the skill composition of the Australian workforce. Changes in the macroeconomic and technology environments make it hard to predict skill shortage. The project expects to develop macroeconomic models quantifying skill-mismatch of university graduates, identify sources of mismatch, highlight gender and generational differences, and estimate associated costs to Australia. The expected outcomes are to help shape policy recommendations on the funding of tertiary education in a changing economic climate. This should provide significant benefits to Australians, as policies shaping the tertiary education system affect individual income and the aggregate economy by determining labour supply and taxpayers' financial burden.Read moreRead less
Protected Action Ballots and Protected Industrial Action under the Fair Work Act: The Impact of Ballot Procedures on Enterprise Bargaining Processes. Under the Fair Work Act 2009 (Cth), lawful industrial action may be taken by employees in support of collective bargaining, provided that they have first authorised the action in a secret ballot. This research project explores the effect of the statutory process by which a bargaining representative of such employees seeks permission from the Fair W ....Protected Action Ballots and Protected Industrial Action under the Fair Work Act: The Impact of Ballot Procedures on Enterprise Bargaining Processes. Under the Fair Work Act 2009 (Cth), lawful industrial action may be taken by employees in support of collective bargaining, provided that they have first authorised the action in a secret ballot. This research project explores the effect of the statutory process by which a bargaining representative of such employees seeks permission from the Fair Work Commission to conduct a ballot. It will examine the impact of the ballot requirement and statutory process on decision-making by bargaining representatives and subsequent employee access to industrial action in order to understand the effect of the regulatory scheme on enterprise bargaining behaviour. It is the first empirical study of strike ballots, analysing an important public policy area.Read moreRead less
Australian supply chain regulation: practical operation and regulatory effectiveness. This project uses empirical research to examine the practical operation and effectiveness of three innovative Australian regulatory models designed to improve working conditions in supply chains in the clothing, long-haul transport and cash-in-transit industries. The project will result in proposals for reform and improved working conditions.
ARC Centre of Excellence in Population Ageing Research. This Centre intends to generate crucial knowledge to inform social and economic responses to population ageing, one of the most important issues of the 21st century. Population ageing exerts unprecedented pressures on social norms and policy institutions, both in Australia and around the world. Leading researchers from a range of disciplines will undertake multidisciplinary research to help governments, businesses, and consumers prepare for ....ARC Centre of Excellence in Population Ageing Research. This Centre intends to generate crucial knowledge to inform social and economic responses to population ageing, one of the most important issues of the 21st century. Population ageing exerts unprecedented pressures on social norms and policy institutions, both in Australia and around the world. Leading researchers from a range of disciplines will undertake multidisciplinary research to help governments, businesses, and consumers prepare for and make better decisions for an ageing world, with consequent social and economic benefits for families and communities expected to flow to Australia, the Asian region and the world.Read moreRead less
Working the gig economy: The organisation of digital platform work. This project aims to reveal the characteristics, motivations and relationships between the three central entities which comprise digital platform work: companies which organise work of different skill and scale in the gig economy; end-user individuals and enterprises; and digital platform workers themselves. This project investigates the organisation of platform work from the perspective of both workers and the intermediaries th ....Working the gig economy: The organisation of digital platform work. This project aims to reveal the characteristics, motivations and relationships between the three central entities which comprise digital platform work: companies which organise work of different skill and scale in the gig economy; end-user individuals and enterprises; and digital platform workers themselves. This project investigates the organisation of platform work from the perspective of both workers and the intermediaries they use to find work. Expected outcomes will contribute g to knowledge of workforce transitions and shifting work/home boundaries This has the potential to informeffective policy responses to platform work with respect to labour law, superannuation regulation, organisational policy and social welfare regimes.Read moreRead less
Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The proj ....Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The project expects to inform policy-makers on these critical issues by analysing field, survey and administrative data on individuals before and after past disasters.Read moreRead less
GABA(B) Receptor Modulation Of Gastrointestinal Function In Health And Disease By Alpha-Conotoxins
Funder
National Health and Medical Research Council
Funding Amount
$689,050.00
Summary
Chronic visceral pain is a common and debilitating condition arising from numerous diseases that affect our internal organs. There is a desperate need for more information about the mechanisms responsible for signalling chronic visceral pain to provide therapies and potentially find a cure for it. Our research focuses on ?-conotoxins (small peptides from marine cone snail venom) as novel potential therapeutic agents for the treatment of chronic visceral pain.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100099
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Comprehensive free access to Australian industrial and workplace law. This project aims to develop an ‘Australian Industrial and Workplace Relations Law Library’ on AustLII. The project will make relevant current law searchable in one location; digitise decisions contained in the major industrial law report series published since Federation; scan other key resources; add dynamic virtual databases; develop data mining tools to better recognise citation information in printed industrial law materi ....Comprehensive free access to Australian industrial and workplace law. This project aims to develop an ‘Australian Industrial and Workplace Relations Law Library’ on AustLII. The project will make relevant current law searchable in one location; digitise decisions contained in the major industrial law report series published since Federation; scan other key resources; add dynamic virtual databases; develop data mining tools to better recognise citation information in printed industrial law materials; and develop citation analysis, visualisation and other analytical tools for industrial and workplace law research. The project hopes to improve research in the field of Australian industrial and workforce relations system and the history and development of work in Australia, and inform policy and debate.Read moreRead less
Women in non-traditional careers: a longitudinal study of female professionals in the mining and resources industries. This project is in line with National Research Priority, strengthening Australia's social and economic fabric, which identifies the importance of research on workforce participation. The main aim of this research is to increase the attraction, participation, development and most importantly, retention of qualified female technical staff in the Australian resource industry. Analy ....Women in non-traditional careers: a longitudinal study of female professionals in the mining and resources industries. This project is in line with National Research Priority, strengthening Australia's social and economic fabric, which identifies the importance of research on workforce participation. The main aim of this research is to increase the attraction, participation, development and most importantly, retention of qualified female technical staff in the Australian resource industry. Analysis of project outputs will directly inform policies and practices to redress the significant skill shortages in the industry. Furthermore enhancing workplace diversity is necessary to create effective and innovative workplaces that reflect the diversity of the broader Australian society.Read moreRead less