Psychosocial Disability And Return To Work In Younger Stroke Survivors
Funder
National Health and Medical Research Council
Funding Amount
$511,216.00
Summary
Each year about 12,000 Australians of working age survive a stroke. These younger survivors have responsibility for generating an income or providing care for families and state that their main objective is to return to work for financial reasons and to help rebuild confidence and independence. This observational 3 year study will determine thefactors are associated with returning to work, improving the wellbeing of thousands of stroke survivors and their families using multivariate regression.
Gynaecological, Oesophageal And Skin Cancer In Australia: Developing The Evidence-base
Funder
National Health and Medical Research Council
Funding Amount
$6,079,935.00
Summary
Our Program addresses cancers of the ovary, uterus, oesophagus and skin (both melanoma and non-melanoma skin cancers). The first three cancers together affect almost 4,000 people and cause more than 2,000 deaths every year while skin cancer affects almost 400,000 Australians each year. Our aims are, first, to understand better how these cancers are caused so that we can try to prevent them in the future; second, to enhance diagnosis of these cancers; and third, to improve the survival and qualit ....Our Program addresses cancers of the ovary, uterus, oesophagus and skin (both melanoma and non-melanoma skin cancers). The first three cancers together affect almost 4,000 people and cause more than 2,000 deaths every year while skin cancer affects almost 400,000 Australians each year. Our aims are, first, to understand better how these cancers are caused so that we can try to prevent them in the future; second, to enhance diagnosis of these cancers; and third, to improve the survival and quality of life for people who are diagnosed with these cancers in Australia.Read moreRead less
A Five Year Follow-up Of People With Type 2 Diabetes & Other States Of Glucose Intolerance And Associated Risk Factors
Funder
National Health and Medical Research Council
Funding Amount
$2,677,855.00
Summary
The Australian Prospective Diabetes Study (APDS) is a 5 year follow-up study established to examine the natural history of diabetes and its complications, as well as heart disease and kidney disease. It is a follow-up to the recently completed AusDiab study and addresses some of the important gaps that exist nationally and internationally in the understanding of the burden of Type 2 diabetes and related problems. AusDiab found that 1 in 4 Australians aged 25 years and over has either diabetes or ....The Australian Prospective Diabetes Study (APDS) is a 5 year follow-up study established to examine the natural history of diabetes and its complications, as well as heart disease and kidney disease. It is a follow-up to the recently completed AusDiab study and addresses some of the important gaps that exist nationally and internationally in the understanding of the burden of Type 2 diabetes and related problems. AusDiab found that 1 in 4 Australians aged 25 years and over has either diabetes or a condition of impaired glucose metabolism (this condition is associated with substantially increased immediate risk of heart disease as well as increased risk of diabetes in the future). This new study-APDS, will be the first Australian and indeed international study of its type. We intend to invite 7000 out of the original 11,247 AusDiab sample to participate. Participants who agree to take part in the follow-up study will be involved in 2 ways: 1. A 6-12 monthly contact with participants by telephone or mail to allow reporting of changes in health and utilisation of health services. 2. A 5 year biomedical follow-up survey. This will involve a survey team travelling around Australia to test the participants for diabetes, heart and kidney disease and cardiovascular risk factors (e.g. blood pressure and cholesterol). It will accurately define how many Australians are likely to develop diabetes (as well as kidney and heart disease) in the future, and who is at highest risk. It is expected that outcomes from this study will provide crucial information for both planning and testing public health policy and for the appropriate allocation of resources including specific treatments of individuals and specific groups with or at risk of Type 2 diabetes and its complications within the Australian population.Read moreRead less
Epidemiology Of Middle-age BHR: A Prospective Study From Childhood To Middle Age
Funder
National Health and Medical Research Council
Funding Amount
$593,840.00
Summary
Increased airway reactivity (BHR) in middle-age increases the risk of chronic respiratory diseases (CRDs) in old age, which are recognised as a major public health problem. Knowledge on the causes of these conditions is currently limited. This project will improve our understanding of the childhood and adult causes of increased reactivity of the airways in middle-age. Such knowledge will help in identifying preventive strategies for middle age BHR and thereby CRDs in old age.
Risk And Prognostic Factors For Breast Cancer Of Different Immunohistochemical Subtypes
Funder
National Health and Medical Research Council
Funding Amount
$294,461.00
Summary
Breast cancer is a heterogeneous disease. Gene expression analysis has identified a number of subtypes that are different with respect to pathology, prognosis, and response to treatment. Building on an existing cohort study, we aim to identify risk and prognostic factors for molecular subtypes of breast cancer.
Allergies And Chronic Respiratory Diseases: Causes, Biological Pathways And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$420,872.00
Summary
Allergies and chronic respiratory diseases are major causes of illness and death in Australia. Worryingly there are still many gaps in knowledge on how best to prevent and manage these diseases. The proposed program will investigate these questions and provide evidence to guide health policy and clinical management. As this program is built on state-of the-art methods and technology, these original Australian findings will be of great importance internationally.
The Epidemiology Of Staphylococcus Aureus And Antibiotic Resistance In Community-acquired Infections
Funder
National Health and Medical Research Council
Funding Amount
$1,267,784.00
Summary
Staphylococcus aureus infections range from boils to life-threatening diseases and are increasingly resistant to antibiotics and difficult to treat. This study follows patients with community-acquired S. aureus infections, and close contacts, for 24 months to see if they carry S. aureus (nose swabs) or develop infection. Our data on risk factors for colonisation and infection will help doctors decide whether to trace and treat contacts of patients to protect households from further infection.