A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Young people, sex, love and the media. This project aims to discover what young Australians are learning about sex, love and relationships from popular media, as well as the impact that it is having on their behaviour and attitudes towards sexuality and intimate relationships. It will make recommendations about how to promote ethical and safe sexual practices and attitudes.
Working from home: New media technology, workplace culture and the changing nature of domesticity. New media technologies are often marketed as liberating people from the workplace, providing flexibility in meeting work obligations. Communication technologies in particular make working from home increasingly possible: laptops, mobile phones and PDAs make any space a potential site for paid labour. This research studies the effect of new media technologies on how work is performed, where and by w ....Working from home: New media technology, workplace culture and the changing nature of domesticity. New media technologies are often marketed as liberating people from the workplace, providing flexibility in meeting work obligations. Communication technologies in particular make working from home increasingly possible: laptops, mobile phones and PDAs make any space a potential site for paid labour. This research studies the effect of new media technologies on how work is performed, where and by whom, to gauge their impact on the community more broadly. It also asks whether these new relationships to work raise the prospect of changing traditional attitudes to the work performed in and outside the home by men and women.Read moreRead less
Optimising Intervention Strategies To Reduce The Burden Of Group A Streptococcus In Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$856,896.00
Summary
Skin sores are highly prevalent in remote Australian Indigenous communities and can lead to invasive infections and rheumatic heart disease. We will develop mathematical models to understand the transmission of skin sores, allowing us to define the optimal extent (household, community, region), timing and triggers for interventions to interrupt transmission. This will guide public health policy in reducing the prevalence of skin sores and scabies, and their accompanying disease burden.
A New Approach to Air Traffic Management to Deliver Significantly Reduced Environmental Impact and System-wide Efficiencies. Aviation is often cited as a major contributor to harmful emissions in the upper atmosphere. The primary outcome of this project is the development of tools that will enable aviation industry stakeholders to optimise the deployment of 4-Dimensional User Preferred Trajectories across Australian airspace. It is expected that this will result in significant environmental bene ....A New Approach to Air Traffic Management to Deliver Significantly Reduced Environmental Impact and System-wide Efficiencies. Aviation is often cited as a major contributor to harmful emissions in the upper atmosphere. The primary outcome of this project is the development of tools that will enable aviation industry stakeholders to optimise the deployment of 4-Dimensional User Preferred Trajectories across Australian airspace. It is expected that this will result in significant environmental benefit, through reductions in fuel burn for each flight, and increases in system effectiveness. The project will enable better analysis of Australian aviation environmental effect, whilst at the same time allowing the aviation industry to continue to contribute to Australia's sustainable economic growth. Read moreRead less
CKD-FIX: A Randomised, Controlled Trial Of Allopurinol In The Slowing Of Kidney Disease Progression
Funder
National Health and Medical Research Council
Funding Amount
$1,917,147.00
Summary
Chronic kidney disease (CKD) is a major public health problem affecting over 1.5 million Australians and is associated with increased risk of death, heart disease and progression to end-stage kidney disease (ESKD). Current treatments to slow progression to ESKD are limited. The CKD-FIX trial aims to find out whether treatment with allopurinol, a commonly used drug for gout prevention, safely and effectively slows CKD progression. This could lead to significant health and economic benefits.
ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit ne ....ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit new cell technologies. The Centre will build critical mass and national focus in bioinformatics to generate the human capital and intellectual property that Australia needs to compete in advanced bioscience and biotechnology.Read moreRead less
Reconstructing land tenure maps of Australia in 3D. Existing land tenure maps of above and below ground, such as apartment ownership, tunnels, and mining, are maintained using 2D drawings. However, the drawings are not structured and valuable for detailed and advanced visualisation, analytics, and simulation, which are essential for testing potential interventions and policy development. This project aims to develop a data validation framework for transforming current drawings and reconstructing ....Reconstructing land tenure maps of Australia in 3D. Existing land tenure maps of above and below ground, such as apartment ownership, tunnels, and mining, are maintained using 2D drawings. However, the drawings are not structured and valuable for detailed and advanced visualisation, analytics, and simulation, which are essential for testing potential interventions and policy development. This project aims to develop a data validation framework for transforming current drawings and reconstructing them into 3D models. The outcomes include validation principles, formal mathematical terms, and computational algorithms. Benefits include a cost-effective onshore alternative to offshore 3D reconstruction practices, efficient land development and infrastructure planning, and fewer property disputes.Read moreRead less
Australian Experiences of Algorithmic Culture on TikTok. This project is the first to systematically investigate how algorithmic content recommendation is shaping everyday Australian cultural experience over time, in the particular context of TikTok—the digital platform where Australians spend the most time online. The project provides critical evidence to support the government's ongoing policy initiatives intended to regulate the activities of digital platforms. Its methodological innovations ....Australian Experiences of Algorithmic Culture on TikTok. This project is the first to systematically investigate how algorithmic content recommendation is shaping everyday Australian cultural experience over time, in the particular context of TikTok—the digital platform where Australians spend the most time online. The project provides critical evidence to support the government's ongoing policy initiatives intended to regulate the activities of digital platforms. Its methodological innovations directly address the challenges of studying commercial platforms' recommender systems through a mixed-method research design combining computational and qualitative analysis, bridging universal and individual perspectives and introducing ‘citizen science’ approaches to the field of platform studies.Read moreRead less
The skin of commerce: the role of plastic packaging in the construction of food security, waste and consumer activism in Australia. Plastic packaging has been important to ensuring food security in Australia, however it is also a major waste burden. This project will critically assess new approaches to reducing plastic packaging in food markets and waste streams and will produce key insights into how sustainable food systems can be organised with less reliance on plastic.