A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Developing An Australian Valuation For The EQ-5D-5L Quality Of Life Instrument
Funder
National Health and Medical Research Council
Funding Amount
$348,357.00
Summary
In the assessment of gains resulting from a health technology, it is standard to consider both mortality and quality of life effects. This project explores how Australians value different components of quality of life. To do this, we are running an online survey called a discrete choice experiment, and analysing the data using a range of cutting-edge econometric techniques. This will allow policy-makers to better reflect people's preferences when making decisions about new technologies.
Optimising Intervention Strategies To Reduce The Burden Of Group A Streptococcus In Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$856,896.00
Summary
Skin sores are highly prevalent in remote Australian Indigenous communities and can lead to invasive infections and rheumatic heart disease. We will develop mathematical models to understand the transmission of skin sores, allowing us to define the optimal extent (household, community, region), timing and triggers for interventions to interrupt transmission. This will guide public health policy in reducing the prevalence of skin sores and scabies, and their accompanying disease burden.
The role of public culture in the construction of contemporary Australian literature. Literature is not simply a body of texts; it is a cultural technology, affected by changing patterns of production and consumption. Witness the 'cult of celebrity', the phenomenal recent growth of literary festivals, literary internet sites, reading groups, changing patterns of literary marketing, education, employment and leisure. Academic scholarship, largely text-based, fails to engage with these public and ....The role of public culture in the construction of contemporary Australian literature. Literature is not simply a body of texts; it is a cultural technology, affected by changing patterns of production and consumption. Witness the 'cult of celebrity', the phenomenal recent growth of literary festivals, literary internet sites, reading groups, changing patterns of literary marketing, education, employment and leisure. Academic scholarship, largely text-based, fails to engage with these public and popular phenomena. Our project develops methods for describing and evaluating how these practices construct literary value and cultural identity, in ways that will bring academic literary analysis into a more informed, more creative engagement with public and popular culture in Australia.Read moreRead less
Optimal management of corrosion and odour problems in sewer systems. Pollutants in wastewater undergo complex changes in sewers, leading to the production and release of odorous and corrosive compounds. Despite major efforts and expenditure by water utilities to mitigate these problems, odorous emissions from sewers are still commonly occurring in urban areas. Furthermore, the value of public assets is significantly diminished due to sewer corrosion, costing hundreds of millions of dollars a yea ....Optimal management of corrosion and odour problems in sewer systems. Pollutants in wastewater undergo complex changes in sewers, leading to the production and release of odorous and corrosive compounds. Despite major efforts and expenditure by water utilities to mitigate these problems, odorous emissions from sewers are still commonly occurring in urban areas. Furthermore, the value of public assets is significantly diminished due to sewer corrosion, costing hundreds of millions of dollars a year in Australia alone. This project is a major joint effort by the Australian water industry and world-leading scientists to generate advanced knowledge and develop effective technologies for optimal odour and corrosion management in sewers, delivering large social, environmental and economic benefits.Read moreRead less
Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in res ....Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in response to ventilation and dynamic wastewater and atmospheric conditions, enabling model-based sewer ventilation design and operation. The project also aims to deliver novel, field-demonstrated ventilation strategies. The project findings will be incorporated in the Australian ventilation design and operation guidelines.Read moreRead less
Special Research Initiatives - Grant ID: SR0354670
Funder
Australian Research Council
Funding Amount
$40,000.00
Summary
Cultural Research Network: Cultural literacies, technologies, identities and histories. The Cultural Research Network's initial disciplinary base will be in cultural, media and communications studies. From this foundation it will build collaborative links with researchers from cultural history, cultural geography, cultural anthropology and creative industries to develop the capacity for innovative research into media and cultural technologies, cultural literacies, cultural histories and identiti ....Cultural Research Network: Cultural literacies, technologies, identities and histories. The Cultural Research Network's initial disciplinary base will be in cultural, media and communications studies. From this foundation it will build collaborative links with researchers from cultural history, cultural geography, cultural anthropology and creative industries to develop the capacity for innovative research into media and cultural technologies, cultural literacies, cultural histories and identities. To facilitate interdisciplinary exchange, the network will establish virtual connections, travelling master classses, seminars and symposia. The network will circulate people as well as ideas and information, bringing established Australian researchers into direct contact with postgraduates and young researchers in these fields, and pursuing international linkages.Read moreRead less
ARC Cultural Research Network. The Cultural Research Network's initial disciplinary base will be in cultural, media, and communications studies. From this foundation it will build collaborative links with researchers from cultural history, cultural geography, cultural anthropology and creative industries to develop innovative research into media and cultural technologies, cultural literacies, cultural histories and identities. To facilitate interdisciplinary exchange the network will establish v ....ARC Cultural Research Network. The Cultural Research Network's initial disciplinary base will be in cultural, media, and communications studies. From this foundation it will build collaborative links with researchers from cultural history, cultural geography, cultural anthropology and creative industries to develop innovative research into media and cultural technologies, cultural literacies, cultural histories and identities. To facilitate interdisciplinary exchange the network will establish virtual connections, travelling master classes, seminars and symposia. The network will circulate people as well as ideas, bringing established Australian researchers into direct contact with postgraduates and young researchers, and pursuing international linkages.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH130200012
Funder
Australian Research Council
Funding Amount
$2,748,358.00
Summary
ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, ....ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, inaccessible remote and deep exploration targets. The Hub will fuse multidimensional data into five dimensional basin models (space and time, with uncertainty estimates) by coupling the evolution of mantle flow, crustal deformation, erosion and sedimentary processes, achieving a quantum leap in basin modelling and petroleum systems analysis.Read moreRead less
Unlocking self-healing bio-concrete through multiscale modelling. Self-healing bio-concrete, which uses bacteria as means to repair cracks, has the potential to revolutionise the construction industry and reduce the infrastructure repair and maintenance cost by billions of dollars annually. To unlock this, we need to understand the bacterial self-healing mechanisms for effective control of the performance. This project will develop a multiscale framework to describe the competing mechanisms betw ....Unlocking self-healing bio-concrete through multiscale modelling. Self-healing bio-concrete, which uses bacteria as means to repair cracks, has the potential to revolutionise the construction industry and reduce the infrastructure repair and maintenance cost by billions of dollars annually. To unlock this, we need to understand the bacterial self-healing mechanisms for effective control of the performance. This project will develop a multiscale framework to describe the competing mechanisms between crack widening and healing at the macro-scale, incorporated with key information of substances diffusion and bio-cementation at the meso- and micro-scales. This will enable to optimise the self-healing of bio-concrete via design–test–learn approach and enhance the durability of structures under sustained loads.Read moreRead less