The Older Australian Twins Study (OATS) Of Healthy Brain Ageing And Age-related Neurocognitive Disorders
Funder
National Health and Medical Research Council
Funding Amount
$940,960.00
Summary
Ageing is associated with cognitive decline and dementia. It is still not completely understood what relative contributions genes and environment play in these. This project is an extension of the Older Australian Twins Study to examine genetic and environmental factors associated with late life brain changes and dementia, and will establish an internationally significant cohort for novel discovery.
Centre Of Research Excellence In Cognitive Health: Evidence, Intervention And Population Modelling
Funder
National Health and Medical Research Council
Funding Amount
$2,499,872.00
Summary
Cognitive health is essential for productivity at all ages. Common chronic diseases such as diabetes, and risk factors such as smoking, can reduce cognitive function and increase risk of cognitive decline. Our Centre aims to build evidence about the things that impact on cognitive health and lead to cognitive decline; to develop methods of reducing cognitive decline; and to measure the impact of cognitive impairment at the national level to inform the government on costs and planning.
Understanding The Impact Of Social, Economic And Geographic Disadvantage On The Health Of Australians In Mid - Later Lif
Funder
National Health and Medical Research Council
Funding Amount
$1,943,571.00
Summary
This research will examine the ways in which social, economic and environmental factors contribute to the health of Australians in mid to later life. It will help identify ways in which policy and preventive programs can contribute to improving health in mid to later life particularly among disadvantaged Australians. We will explore in detail social, economic and environmental factors in 100,000 people aged 45 and over; this will be the largest study of its kind ever undertaken in Australia. We ....This research will examine the ways in which social, economic and environmental factors contribute to the health of Australians in mid to later life. It will help identify ways in which policy and preventive programs can contribute to improving health in mid to later life particularly among disadvantaged Australians. We will explore in detail social, economic and environmental factors in 100,000 people aged 45 and over; this will be the largest study of its kind ever undertaken in Australia. We will examine the relationship between these social, economic factors, and lifestyle factors such as smoking, physical activity, environmental and obesity. This will enable us to identify where programs and policies should be directed to most rapidly improve the health of disadvantaged Australians.Read moreRead less
Two-stage ignition and flame stabilisation in engine-relevant conditions. This project aims to reveal the mechanisms of ignition and flame stabilisation in the temperature and pressure conditions that exist in diesel engines, understanding of which is currently very limited despite their significant bearing on pollutants and fuel efficiency. Using massively parallel supercomputing resources, the most detailed, direct numerical simulations of ignition and flame stabilisation to date will be perfo ....Two-stage ignition and flame stabilisation in engine-relevant conditions. This project aims to reveal the mechanisms of ignition and flame stabilisation in the temperature and pressure conditions that exist in diesel engines, understanding of which is currently very limited despite their significant bearing on pollutants and fuel efficiency. Using massively parallel supercomputing resources, the most detailed, direct numerical simulations of ignition and flame stabilisation to date will be performed - they will be three-dimensional and use a detailed chemistry model able to account for low-temperature kinetics and two-stage ignition. Analysis of these data aims to reveal how ignition and flame stabilisation depends on key turbulence and chemical kinetic parameters, thus contributing to developing low-emissions diesel engines.Read moreRead less
High-Grade CO2 Concrete for Low Life-Cycle Costing and Emissions. This proposal solves Australia’s concrete-waste-storage problems, and lowers the life-cycle costs and greenhouse-gas emissions by creating CO2 Concrete as a world-first material for high-grade applications. Using an automation system with high-tech software, innovative mixing techniques are proposed to maximise bonding at interfacial transition zones, strengthening CO2 Concrete's quality. The new material CO2 Concrete is created, ....High-Grade CO2 Concrete for Low Life-Cycle Costing and Emissions. This proposal solves Australia’s concrete-waste-storage problems, and lowers the life-cycle costs and greenhouse-gas emissions by creating CO2 Concrete as a world-first material for high-grade applications. Using an automation system with high-tech software, innovative mixing techniques are proposed to maximise bonding at interfacial transition zones, strengthening CO2 Concrete's quality. The new material CO2 Concrete is created, whose strength and durability are comparable to virgin concrete's, leading to new CO2-Concrete specifications for trials in the construction industry. This diversifies the construction industry, reduces landfill area, greening up Australia on a global scale.Read moreRead less
Multi-service assessment of intertidal treatment wetlands. This project aims to investigate the use of constructed intertidal wetlands to reduce nitrogen pollution while providing co-benefits including carbon sequestration and biodiversity. This research will generate a holistic assessment of the services, disservices, and cost-effectiveness of intertidal treatment wetlands compared to traditional wastewater treatment approaches. Expected outcomes include a full-scale multi-disciplinary environm ....Multi-service assessment of intertidal treatment wetlands. This project aims to investigate the use of constructed intertidal wetlands to reduce nitrogen pollution while providing co-benefits including carbon sequestration and biodiversity. This research will generate a holistic assessment of the services, disservices, and cost-effectiveness of intertidal treatment wetlands compared to traditional wastewater treatment approaches. Expected outcomes include a full-scale multi-disciplinary environmental and economic assessment of a constructed treatment wetland in a new urban development, providing industry and government partners the knowledge required to broaden uptake of intertidal wetlands as a cost-effective solution to growing levels of coastal anthropogenic pollution.Read moreRead less
Het-Crete: High-Grade Chemical-Treated Heterogeneous Recycled Concrete. Of over 20 million tons of mixed construction and demolition waste generated annually, only 5% is recycled and less than 1% is adopted for low-grade construction activities. This innovative research aims to solve Australia’s mixed construction and demolition waste disposal problem and lower its greenhouse-gas emissions at the same time. The research develops Het-Gregate with novel chemical admixtures and greenhouse-gas emiss ....Het-Crete: High-Grade Chemical-Treated Heterogeneous Recycled Concrete. Of over 20 million tons of mixed construction and demolition waste generated annually, only 5% is recycled and less than 1% is adopted for low-grade construction activities. This innovative research aims to solve Australia’s mixed construction and demolition waste disposal problem and lower its greenhouse-gas emissions at the same time. The research develops Het-Gregate with novel chemical admixtures and greenhouse-gas emissions to create Het-Crete, with new mixing techniques for its an optimal performance high-grade concrete. Life-cycle analyses will be conducted to generate Het-Crete specifications for the industry. This will significantly elevate Australia’s world standing in recycled concrete research.Read moreRead less
Accelerating Consolidation and Closure of Mine Tailings Storage Facilities. All mining operations involve the production of waste. Many regard such waste (tailings) and their environmentally acceptable storage as constituting the largest waste problem on Earth because of the enormous damage and loss-of-life that have resulted from failures of tailings storage facilities. This project focuses on a dewatering technology, electro-osmosis (EO), which has yet to be fully operationalised, for improvin ....Accelerating Consolidation and Closure of Mine Tailings Storage Facilities. All mining operations involve the production of waste. Many regard such waste (tailings) and their environmentally acceptable storage as constituting the largest waste problem on Earth because of the enormous damage and loss-of-life that have resulted from failures of tailings storage facilities. This project focuses on a dewatering technology, electro-osmosis (EO), which has yet to be fully operationalised, for improving the strength, stability and settlement characteristics of the tailings. Sophisticated testing will be undertaken at three scales (lab, meso and, most importantly, field), as well as the development of generic numerical models, to create practical guidelines to facilitate the implementation of EO in mines around the world.Read moreRead less
A novel ion-selective membrane for efficient lithium recovery . This project aims to fabricate a novel membrane that display selective lithium recovery from brine in a renewable energy driven electrochemical membrane technology. The fabrication of lithium selective membranes embedded with nanomaterials and metal organic framework will create new knowledge on the dynamics of ion-size sieving and accelerating lithium transportation. This project will provide significant environmental and economic ....A novel ion-selective membrane for efficient lithium recovery . This project aims to fabricate a novel membrane that display selective lithium recovery from brine in a renewable energy driven electrochemical membrane technology. The fabrication of lithium selective membranes embedded with nanomaterials and metal organic framework will create new knowledge on the dynamics of ion-size sieving and accelerating lithium transportation. This project will provide significant environmental and economic benefit by establishing a rapid and chemical free method to recover lithium affordably and orders of magnitude more efficiently than hard rock extraction. This project will bring significant commercial benefits to Australian mining industry, desalination and water treatment sectors.Read moreRead less
Integrated solar to chemical production and membrane concentration system. The efficient conversion of low-cost raw materials to high-value chemicals using solar energy has been a long sought-after goal. This project aims to create an integrated photoreactor and membrane separation system for efficient photocatalytic water splitting. The integrated system will efficiently produce hydrogen and ultrapure hydrogen peroxide, a critical and costly reagent used in the semiconductor and solar panel man ....Integrated solar to chemical production and membrane concentration system. The efficient conversion of low-cost raw materials to high-value chemicals using solar energy has been a long sought-after goal. This project aims to create an integrated photoreactor and membrane separation system for efficient photocatalytic water splitting. The integrated system will efficiently produce hydrogen and ultrapure hydrogen peroxide, a critical and costly reagent used in the semiconductor and solar panel manufacturing industries. The integrated system addresses current challenges in the production of high-quality hydrogen peroxide and demonstrates a practical solar-to-chemical process with economic benefits. It also advances knowledge in the fields of nanomaterials engineering, photocatalytic devices, and membrane technology.Read moreRead less