The Role Of The Innate Immune System In The Immunopathogenesis Of Malaria
Funder
National Health and Medical Research Council
Funding Amount
$82,554.00
Summary
Malaria is common worldwide, affecting 600 million people. As with many infectious diseases, it the severity of a malaria infection is not only dictated by the parasite, but also the body’s immune response to the infection. This study looks at cells that contribute to the immediate immune response in two major clinical syndromes of malaria affecting women and children: cerebral malaria and malaria of pregnancy. By understanding the immune response, we gain insights into how to limit disease.
A Detailed Asssessment Of Severe Malaria And Severe Non Malarial Illness In Papua New Guinean Children.
Funder
National Health and Medical Research Council
Funding Amount
$39,171.00
Summary
PNG has the highest infant and childhood mortality in the Pacific with malaria accounting for 15% of infant mortality. Diagnosing and investigating malaria in this setting is hard because the symptoms are similar to other diseases. We aim to accurately describe clinical and laboratory features and risk factors for malaria, severe non malarial disease and mortality. We are investigating an outbreak of unexplained encephalitis as well.