Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential t ....Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential to result in great commercial value for Australia. This project will contribute significantly to Australian research capacity in cutting-edge technologies in active vibration control. The collaboration between UNSW and the Maritime Platforms Division of DSTO will promote technology transfer and enhance Defence research expertise.Read moreRead less
Small Scale Turbulence. The thrust of the project is to gain a fundamental understanding of turbulence, which is the usual state of fluid motion. The focus will be principally on the smallest length scales of turbulence because of the potential that exists for developing a theoretical framework which can predict the behaviour of these scales accurately. Important insight will be gained into the manner in which temperature is mixed and convected by a turbulent flow.
Information Encoding By Temporal Structure Of Afferent Spike Trains
Funder
National Health and Medical Research Council
Funding Amount
$231,175.00
Summary
Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreve ....Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreversible.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
A Multi-national Trial To Predict Treatment Response In Subtypes Of Depression
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Treatment of MDD using trial and error can have serious consequences. It can prolong the patient’s suffering (depression is associated with substantial morbidity, and mortality), prolong their absence from work and other productive activity and increase the burden on their family-carers. This multi-national study will collect genetics, brain function and behavioural data from a large number of participants, allowing for sensitive predictors of response to be determined.
In situ neutron diffraction mapping of tri-axial stress distributions in particulate systems. Compacting powders, which are critical in industries such as metal, advanced ceramic and pharmiceutical manufacturing, will be studied in real time using advanced neutron diffraction techniques. This will allow the three-dimensional mapping of stresses and strains within small volumes of the powder deep inside realistic compaction equipment.
Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing prob ....Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing problem. The project aims to achieve this by applying an innovative combination of cutting-edge 3D printing technology, advanced computational modelling and design techniques to produce a next-generation bioceramic scaffold with optimised architecture. This approach aims also to enable the possibility of producing custom-made implants for individual requirements.Read moreRead less
An experimental and theoretical programme of research to resolve major obstruction-to-flow problems in bins and stockpiles. Many of Australia's industries rely on the efficient storage and handling of bulk solids materials such as minerals, chemicals, food-stuffs, agricultural products and pharmeceuticals. Often the handling processes are inefficient to the extent of affecting the economics of the industry. Here we propose two projects addressing those inefficiences resulting from stable obstr ....An experimental and theoretical programme of research to resolve major obstruction-to-flow problems in bins and stockpiles. Many of Australia's industries rely on the efficient storage and handling of bulk solids materials such as minerals, chemicals, food-stuffs, agricultural products and pharmeceuticals. Often the handling processes are inefficient to the extent of affecting the economics of the industry. Here we propose two projects addressing those inefficiences resulting from stable obstructions, such as "rat-holes", and those experimental arising from the unusual flow characteristics of fine powders. The major objectives are to use experimental and advanced mathematical modelling techniques, to produce reliable design models which minimise the occurrence of stable obstructions and provide reliable methods for increasing fine powder flow rates.Read moreRead less
Mathematical modelling of two-phase industrial granular flows. In many industrial processes involving flowing granular materials, the effect of air pressure can be significant. Such examples include pneumatic conveying, lock hoppers and air-impact moulding. The effect of pressurised air on a granular material can either compact it, or can cause sudden large flows. To model such complex phenomena, the frictional effects between the air and the solid granules must be accurately incorporated into a ....Mathematical modelling of two-phase industrial granular flows. In many industrial processes involving flowing granular materials, the effect of air pressure can be significant. Such examples include pneumatic conveying, lock hoppers and air-impact moulding. The effect of pressurised air on a granular material can either compact it, or can cause sudden large flows. To model such complex phenomena, the frictional effects between the air and the solid granules must be accurately incorporated into a two-phase continuum mechanical model for granular materials. This proposal will develop advanced mathematical models and computational procedures to predict complex two-phase granular flows for industrial problems.Read moreRead less
Biotransport design for engineering microenvironment in scaffolds. Tissue engineering signifies an exciting opportunity to solve shortage of transplantable tissues. This project targets a critical issue in engineering thick tissue and aims to introduce computational structural optimisation to biotransport problems. The optimal scaffold is expected to create a more desirable microenvironment for better tissue growth.