Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100096
Funder
Australian Research Council
Funding Amount
$325,000.00
Summary
High resolution atomic force microscopy facility for bionanotechnology. This project aims to establish a collaborative high resolution atomic force microscopy facility. Nanoscale surface structure and the complex structure/mechanical-functional relationships underpin many biological processes, and understanding cell systems at the molecular level is expected to lead to scientific knowledge and therapeutic and other biotechnological applications. Expected outcomes include innovations in advanced ....High resolution atomic force microscopy facility for bionanotechnology. This project aims to establish a collaborative high resolution atomic force microscopy facility. Nanoscale surface structure and the complex structure/mechanical-functional relationships underpin many biological processes, and understanding cell systems at the molecular level is expected to lead to scientific knowledge and therapeutic and other biotechnological applications. Expected outcomes include innovations in advanced manufacturing in the pharmaceutical and medical devices industries, underpinning economic returns from new industries.Read moreRead less
Understanding how mitochondria divide. This project aims to investigate the molecular mechanism by which mitochondria divide. Mitochondria are the powerhouse within our cells, and they grow and divide in our cells to ensure that they are transferred to daughter cells and also so that older mitochondria can be turned over. The project plans to build on the discovery of mitochondrial membrane proteins that are involved in fission. The results of the project could provide fundamental new knowledge ....Understanding how mitochondria divide. This project aims to investigate the molecular mechanism by which mitochondria divide. Mitochondria are the powerhouse within our cells, and they grow and divide in our cells to ensure that they are transferred to daughter cells and also so that older mitochondria can be turned over. The project plans to build on the discovery of mitochondrial membrane proteins that are involved in fission. The results of the project could provide fundamental new knowledge into how the mitochondrial division machine assembles and how mitochondrial fate is determined.Read moreRead less
Autotransporter assembly: new insights and biotechnological potential. The objective of this project is to improve our understanding of a fundamental biological problem: how autotransporters are assembled into cellular membranes. Autotransporters are a large family of bacterial proteins that play key roles in the pathogenesis of several infectious diseases. Currently, the precise mechanism by which disease-causing molecules are assembled into the outer membranes of bacteria and mitochondria is p ....Autotransporter assembly: new insights and biotechnological potential. The objective of this project is to improve our understanding of a fundamental biological problem: how autotransporters are assembled into cellular membranes. Autotransporters are a large family of bacterial proteins that play key roles in the pathogenesis of several infectious diseases. Currently, the precise mechanism by which disease-causing molecules are assembled into the outer membranes of bacteria and mitochondria is poorly understood. The knowledge that the project develops may inform future strategies aimed at the rational treatment of bacterial and mitochondrial diseases.Read moreRead less
Superhydrophobic fabrics for solar desalination of water. This project will further strengthen Australia's world leading position in water desalination technology and advanced fibrous materials research. It will lead to new membrane materials and techniques for high-efficiency, low-cost and energy-saving desalination of sea/saline water, which will have significant social and economic benefits.
Australian Laureate Fellowships - Grant ID: FL180100029
Funder
Australian Research Council
Funding Amount
$2,545,000.00
Summary
Nanoionics: Engineering ion transport with two-dimensional materials. This project aims to use graphene and other emerging two-dimensional materials to investigate and manipulate ion transport in nanoscale channels. Nanoionics focuses on understanding ions for transport and storage in nanoscale systems, central to numerous technologies related to water, energy and biomedicine. The project will provide sophisticated methods for revolutionary technological innovations to solve problems in several ....Nanoionics: Engineering ion transport with two-dimensional materials. This project aims to use graphene and other emerging two-dimensional materials to investigate and manipulate ion transport in nanoscale channels. Nanoionics focuses on understanding ions for transport and storage in nanoscale systems, central to numerous technologies related to water, energy and biomedicine. The project will provide sophisticated methods for revolutionary technological innovations to solve problems in several industries including manufacturing, mining, water management and bioengineering. Providing access to previously unavailable structures and materials, the project will support Australia’s manufacturing sector by transforming established industries with next generation technologies. The project will also build capacity of nanoionics engineers and provide intellectual property for commercialised products.Read moreRead less
Development of technologies to monitor multimolecular complexes. Development of technologies to monitor multimolecular complexes. This project aims to develop technologies to monitor how proteins and their interacting molecules (such as hormones) form multi-component complexes, and how these complexes function in the cell, including movement from the cell surface, into different cellular compartments and back up to the surface. These technologies are expected to enable monitoring in live cells i ....Development of technologies to monitor multimolecular complexes. Development of technologies to monitor multimolecular complexes. This project aims to develop technologies to monitor how proteins and their interacting molecules (such as hormones) form multi-component complexes, and how these complexes function in the cell, including movement from the cell surface, into different cellular compartments and back up to the surface. These technologies are expected to enable monitoring in live cells in real-time with high sensitivity. This project could have broad benefits for and affect study of all aspects of the life sciences at the cellular and molecular levels. How these protein complexes function in cells underpins much of our understanding of biology, and technological tools.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100427
Funder
Australian Research Council
Funding Amount
$446,000.00
Summary
Engineered multifunctional membranes for aqueous organic redox flow battery. This project aims to develop multifunctional membranes with high ion conductivity and selectivity and high energy density to address the key challenges in the development of aqueous organic redox flow battery for renewable energy storage. The project will develop novel methodologies for precisely tuning and functionalising microporous materials to achieve cost-effective and scalable fabrication of membranes with multi-f ....Engineered multifunctional membranes for aqueous organic redox flow battery. This project aims to develop multifunctional membranes with high ion conductivity and selectivity and high energy density to address the key challenges in the development of aqueous organic redox flow battery for renewable energy storage. The project will develop novel methodologies for precisely tuning and functionalising microporous materials to achieve cost-effective and scalable fabrication of membranes with multi-functions, thus improving the energy efficiency and retaining the cycling capacity of redox flow batteries. The advancement of multifunctional membranes will enhance the efficiency of storage of intermittent and fluctuating renewable resources, thereby contributing to the reduction of carbon footprint in Australia. Read moreRead less
Development of Solar-induced, Dark-active Photocatalytic Membranes for Water Disinfection. Stormwater is one of the last freshwater resources that has not been utilised to its full potential. However, large amount of faecal pathogens in stormwater limit its harvesting practice.This project aims at addressing this significant problem by developing the next generation of photocatalytic membranes for stormwater disinfection. The proposed membranes not only are passive water treatment technology whi ....Development of Solar-induced, Dark-active Photocatalytic Membranes for Water Disinfection. Stormwater is one of the last freshwater resources that has not been utilised to its full potential. However, large amount of faecal pathogens in stormwater limit its harvesting practice.This project aims at addressing this significant problem by developing the next generation of photocatalytic membranes for stormwater disinfection. The proposed membranes not only are passive water treatment technology which only utilises solar energy, but also are operated regardless of weather, even at night. The results will provide new insights on development of future water treatment technologies. This project will also raise Australia’s credibility and competitiveness in the water and membrane industries.Read moreRead less
Molecular insights into bacterial metal ion homeostasis and toxicity. This project aims to measure bacterial cellular metal concentrations, elucidate mechanisms cells use to adapt to changing extracellular metal concentrations, and reveal the molecular targets of metal toxicity. Metal ions are essential to all forms of life, and half of all proteins use metal ions for cellular chemical processes. However, how cells precisely balance sufficient metal ions for essential cellular chemistry without ....Molecular insights into bacterial metal ion homeostasis and toxicity. This project aims to measure bacterial cellular metal concentrations, elucidate mechanisms cells use to adapt to changing extracellular metal concentrations, and reveal the molecular targets of metal toxicity. Metal ions are essential to all forms of life, and half of all proteins use metal ions for cellular chemical processes. However, how cells precisely balance sufficient metal ions for essential cellular chemistry without accumulating a toxic excess (metal homeostasis) is poorly understood. Discovering the roles of metal ions in bacterial cells will be key to defining the chemical biology of living systems and will provide information essential to understanding how microbes adapt to changing environments.Read moreRead less
Superwettability effects on oil-mist coalescing fibrous filters. This project aims to provide new knowledge about how to use surface engineering techniques to produce highly efficient, energy-saving fibrous filters for separating oil mists from air streams. The focus is to address the challenge of the low efficiency of current generation coalescing filters for removal of oil mists smaller than one micrometre. The project will result in new methods to precisely control fibre surface wettability a ....Superwettability effects on oil-mist coalescing fibrous filters. This project aims to provide new knowledge about how to use surface engineering techniques to produce highly efficient, energy-saving fibrous filters for separating oil mists from air streams. The focus is to address the challenge of the low efficiency of current generation coalescing filters for removal of oil mists smaller than one micrometre. The project will result in new methods to precisely control fibre surface wettability and oil drainage within fibrous filters. The new knowledge and coalescing filters developed will benefit scientific and industrial fields including metal processing, automotive, engineering and manufacturing, electronics, food, hospital, mining, pharmaceuticals and energy generation.Read moreRead less