Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and ....Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and remediation efforts and will also assist in the understanding of the normal process of reading acquisition in children.Read moreRead less
NeuroSleep: The Centre For Translational Sleep And Circadian Neurobiology
Funder
National Health and Medical Research Council
Funding Amount
$2,659,061.00
Summary
NeuroSleep, the Centre for Translational Sleep and Circadian Neurobiology, will foster innovative clinical research and translation to develop national capacity in understanding how sleep disorders and dysfunction of the body clock impact on health. The Centre will focus its activities on the two-way relationship between disrupted sleep and body clock systems and brain disorders. Our goal is to improve brain performance, workplace safety and health outcomes in patients with sleep and circadian d ....NeuroSleep, the Centre for Translational Sleep and Circadian Neurobiology, will foster innovative clinical research and translation to develop national capacity in understanding how sleep disorders and dysfunction of the body clock impact on health. The Centre will focus its activities on the two-way relationship between disrupted sleep and body clock systems and brain disorders. Our goal is to improve brain performance, workplace safety and health outcomes in patients with sleep and circadian dysfunction and in the general community.Read moreRead less
Modifying The Trajectory Of Insidious Late Life Cognitive Decline Using Computerised Cognitive Training
Funder
National Health and Medical Research Council
Funding Amount
$743,152.00
Summary
Supervised, group-based computerised cognitive training (CCT) is a safe and effective intervention to maintain cognition in healthy older adults. This project will examine the extent to which CCT can attenuate or even reverse the rate of decline in older people with previously documented cognitive decline, as well as strategies to maintain CCT effects in the long term.
Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encodi ....Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encoding and retrieval processes, the model can assess how changes in different sources of interference modulate performance through the trajectory of early development. Hierarchical Bayesian estimation aims to enable a simultaneous account of multiple tasks and support future deployment in applied contexts.Read moreRead less
The Psychology of Misinformation—Towards A Theory-driven Understanding. The project aims to develop a psychological theory of misinformation effects. Misinformation influences people’s memory, reasoning and decision-making even after corrections – it thus poses a significant challenge for science and society. Through the combination of systematic experimentation with theory-driven computational modelling, the project will strive to concurrently consider individual-level cognition and the impact ....The Psychology of Misinformation—Towards A Theory-driven Understanding. The project aims to develop a psychological theory of misinformation effects. Misinformation influences people’s memory, reasoning and decision-making even after corrections – it thus poses a significant challenge for science and society. Through the combination of systematic experimentation with theory-driven computational modelling, the project will strive to concurrently consider individual-level cognition and the impact of sociocultural context. It is anticipated that this novel integrative approach will substantially expand our understanding of misinformation effects, and that this theoretical progress will result in the formulation of specific communication strategies to reduce the impact of misinformation on society.Read moreRead less
An Examination Of Motor Functioning In Autism And Asperger's Disorder: An Analysis Of Gait & Cortical Brain Activity.
Funder
National Health and Medical Research Council
Funding Amount
$120,220.00
Summary
Autism is a developmental disorder characterised by a triad of deficits: delayed and atypical language development, impaired development of social skills, and ritualistic and stereotypic behaviour. Although not part of the standard diagnosis, movement disorders and gait abnormalities have been clinically observed in autism similar to those seen in Parkinson's disease. In addition, individuals with Asperger's disorder may appear more clumsy, have a stiff or awkward way of walking, and exhibit poo ....Autism is a developmental disorder characterised by a triad of deficits: delayed and atypical language development, impaired development of social skills, and ritualistic and stereotypic behaviour. Although not part of the standard diagnosis, movement disorders and gait abnormalities have been clinically observed in autism similar to those seen in Parkinson's disease. In addition, individuals with Asperger's disorder may appear more clumsy, have a stiff or awkward way of walking, and exhibit poor coordination in posture and gesture. It has been suggested that there is disruption within the basal-ganglia-thalamocortical circuitry (the region connecting the frontal and sub-cortical structures), which may cause the motor dysfunction seen in autism and Asperger's disorder. Few studies have attempted to isolate particular stages of motor functioning which may account for the coordination and motor delay observed clinically in autism and Asperger's disorder. A recent study of ours found evidence to suggest that motor planning deficiencies may account for the 'clumsy' movement patterns frequently reported in the autism - Asperger's disorder literature. Therefore, the aim of this research is to provide a comprehensive neurobehavioural and neurophysiological analysis of motor functioning in young people with autism and Asperger's disorder to further examine the exact stages of motor processing which are deficient in these disorder groups. Recent retrospective studies have shown that even as infants children with autism exhibit clear features of motor disturbance, which, if detected and clearly defined, could advance early diagnosis. In addition to advancing the clinical definition of autism and Asperger's disorder, a careful examination of motor disturbance may also illuminate the neurobiological underpinnings of these disorders.Read moreRead less
Special Research Initiatives - Grant ID: SR0354596
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Perception and Action in Auditory Scenes (PAAS): Neural, Behavioural, Computational and Mechanical Systems. Auditory scenes are temporal and ephemeral yet pervasively influence human life. How humans negotiate such scenes has not been solved, a fact highlighted by attempts to build machines to respond to speech, warnings etc., in real-world situations with room reverberation, different talkers, and background noise. No one discipline can solve such problems. In this network outstanding researche ....Perception and Action in Auditory Scenes (PAAS): Neural, Behavioural, Computational and Mechanical Systems. Auditory scenes are temporal and ephemeral yet pervasively influence human life. How humans negotiate such scenes has not been solved, a fact highlighted by attempts to build machines to respond to speech, warnings etc., in real-world situations with room reverberation, different talkers, and background noise. No one discipline can solve such problems. In this network outstanding researchers from physical, medical, human, and social sciences with interests in speech, music and audition will provide insights into how humans and machines localize, recognize, interpret and produce auditory events, and advance frontier technologies, e.g., automatic speech recognition, hearing prostheses, auditory monitoring/warning systems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347607
Funder
Australian Research Council
Funding Amount
$306,000.00
Summary
FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged ex ....FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged expertise as well as priority within their respective institutions. In addition, it will facilitate wide-ranging collaborative arrangements to further develop and exploit this research area.Read moreRead less
Using written language to probe speech recognition models. Speech recognition models fall into two principal classes, with fundamentally different processing architectures. Feedback models (e.g. TRACE, McClelland & Elman, 1986) allow lexical knowledge to exert top-down control over phonemic analysis. Feedforward models (e.g. Merge, Norris, McQueen & Cutler, 2000) assume that information flow is entirely bottom-up. Our project adopts an innovative approach to testing between these model classe ....Using written language to probe speech recognition models. Speech recognition models fall into two principal classes, with fundamentally different processing architectures. Feedback models (e.g. TRACE, McClelland & Elman, 1986) allow lexical knowledge to exert top-down control over phonemic analysis. Feedforward models (e.g. Merge, Norris, McQueen & Cutler, 2000) assume that information flow is entirely bottom-up. Our project adopts an innovative approach to testing between these model classes, by examining the influence of written-word knowledge on speech perception. To distinguish the models, contrasts must test different processing levels and examine strategy effects. TRACE favors broad effects with limited strategic influence; Merge favors lexical effects that are necessarily sensitive to strategic factorsRead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882345
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
A 3.0 Tesla MRI system for human cognitive neuroscience research. For the first time scientists are beginning to reveal the complex relationship between human brain function and behaviour. These advances have stemmed almost exclusively from the development of sophisticated brain scanning techniques that provide high-resolution images of physiological changes associated with perceptual, cognitive and motor behaviours. This application seeks support for a state-of-the-art scanner to obtain high-re ....A 3.0 Tesla MRI system for human cognitive neuroscience research. For the first time scientists are beginning to reveal the complex relationship between human brain function and behaviour. These advances have stemmed almost exclusively from the development of sophisticated brain scanning techniques that provide high-resolution images of physiological changes associated with perceptual, cognitive and motor behaviours. This application seeks support for a state-of-the-art scanner to obtain high-resolution images of the brain as healthy adults perceive, think, learn, remember and decide. The facility will enable Australian scientists to understand the complex links between brain and behaviour in health and disease.Read moreRead less