Using New Methods To Unravel The Genetics Of Complex Disorders
Funder
National Health and Medical Research Council
Funding Amount
$316,444.00
Summary
Advances in genomics have revolutionised research in the genetics of complex traits, but much of the genetic risk to disease remains unexplained. This project aims to utilise and integrate data from the latest genomic technologies such as next-generation sequencing, methylation arrays and gene expression arrays collected from large cohorts both in the United States and Australia to uncover the biological changes necessary for disease onset.
Improving Mental Health Screening For Aboriginal And Torres Strait Islander Pregnant Women And Mothers Of Young Children
Funder
National Health and Medical Research Council
Funding Amount
$1,369,612.00
Summary
Mental health during and after pregnancy is important for the well-being of mother and infant. Unfortunately Aboriginal women in remote Australia have high levels of anxiety and depression, which can have significant short and long-term impacts on both mother and child. Currently these issues are often not identified and if identified services may not feel equipped to address them. This study aims to improve screening for, and contribute to addressing, perinatal mental health issues.
The neocortex is the region of the brain that underlies all cognitive functions. Mental disorders, such as schizophrenia, occur when the communication between nerve cells in the neocortex breaks down. We propose to make electrical measurements from the thin processes of neurons that receive input from widely separated neocortical areas to understand how areas of the neocortex are functionally interlinked, with the ultimate aim to identify how these processes are disturbed in mental disorders.
Improving Cardiovascular Health And Quality Of Life In People With Severe Mental Illness: A Randomised Trial Of A ‘partners In Health’ Intervention
Funder
National Health and Medical Research Council
Funding Amount
$960,320.00
Summary
People with severe mental illness die 13-30 years earlier than other people, mostly from physical illnesses especially cardiovascular disease. Physical health care services are poor for these patients and need urgent improvement. Our team has developed a process to deliver good physical health care using the Flinders Program and recovery framework. This project evaluates the effectiveness and cost-effectiveness of the process, and shows how health services can deliver physical health care.
Improving The Identification, Management And Outcome Of People With Depression And Other Chronic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
My research is designed to reduce depression and help people with chronic disease have a better quality of life. I will work with Aboriginal and/or Torres Strait Islander communities to improve how depression is identified, prevented and treated. I will work with the general community who have major depression, depression that is difficult to treat and people with depression and chronic disease to improve their outcomes. I will also aim to improve the recovery of people who have had a stroke.
Developmental Stages Of Cardiovascular Risk Factors And Their Public Health Impact: A Life Course Perspective
Funder
National Health and Medical Research Council
Funding Amount
$380,558.00
Summary
Using a life course approach, the aims of this study are to (a) investigate the developmental stages (pre-natal, childhood and adolescence) of cardiovascular (CVD) risk factors in young adulthood; (b) identify what is influencing these developmental stages either directly or indirectly and (c) quantify the public health burden of these stages and individual factors. Findings will enhance our understanding of the developmental stages of CVD and their public health burden.
Regulation Of The Beta-secretase (BACE1) By Glycosaminoglycans
Funder
National Health and Medical Research Council
Funding Amount
$561,212.00
Summary
Alzheimer's disease is the leading cause of dementia in the elderly. Because of the prolonged institutionalisation of patients, it is a major health care burden. This project aims to develop novel drugs which can treat Alzheimer's disease by inhibiting production of the protein which causes the neurodegeneration.
From Broome To Berrima: Building Australia-wide Research Capacity In Indigenous Offender Health And Health Care Delivery
Funder
National Health and Medical Research Council
Funding Amount
$3,018,575.00
Summary
Australia has the highest Indigenous incarceration rate in the OECD which impacts profoundly on Indigenous communities. Further, offender populations endure a greater health burden compared with the general community. This grant develops much needed capacity in offender health research, building a team of Indigenous researchers, and creating an Australia-wide network for sharing knowledge in this field. Outcomes will include better Indigenous offender health services and improved health and well ....Australia has the highest Indigenous incarceration rate in the OECD which impacts profoundly on Indigenous communities. Further, offender populations endure a greater health burden compared with the general community. This grant develops much needed capacity in offender health research, building a team of Indigenous researchers, and creating an Australia-wide network for sharing knowledge in this field. Outcomes will include better Indigenous offender health services and improved health and wellbeing for this marginalised population.Read moreRead less