Evolutionary genetics of kin recognition and task specialization in termite societies. Social insects must be able to recognize kin and task specialize in order to maintain colony cohesion and maximize colony labour, respectively. While it is known that kin recognition and task specialization are two key mechanisms underpinning insect societies, the extent to which their expression is mediated by genetic versus environmental variables is not known. This project integrates classic approaches to t ....Evolutionary genetics of kin recognition and task specialization in termite societies. Social insects must be able to recognize kin and task specialize in order to maintain colony cohesion and maximize colony labour, respectively. While it is known that kin recognition and task specialization are two key mechanisms underpinning insect societies, the extent to which their expression is mediated by genetic versus environmental variables is not known. This project integrates classic approaches to the study of animal behaviour with recent advances in molecular genetics to test, for the first time, the role that genetic variables have in mediating kin recognition and task specialization in a major group of social insects, the termites.Read moreRead less
Solving Darwin's dilemma: Molecular analysis of worker sterility in social insects. One of Darwin's greatest puzzles was how natural selection resulted in worker sterility in social insects. We now know from mathematical modelling that a gene that causes sterility in workers can be at a selective advantage if it increases the reproductive success of queens. This project will take the only known gene that causes sterility, 'Anarchy' from honey bees, and determine how this gene evolved. We will de ....Solving Darwin's dilemma: Molecular analysis of worker sterility in social insects. One of Darwin's greatest puzzles was how natural selection resulted in worker sterility in social insects. We now know from mathematical modelling that a gene that causes sterility in workers can be at a selective advantage if it increases the reproductive success of queens. This project will take the only known gene that causes sterility, 'Anarchy' from honey bees, and determine how this gene evolved. We will determine if Anarchy is the same gene that causes sterility in all social insects, or only in honey bees. The project will be at the forefront of international research by providing a molecular perspective to Darwin's greatest dilemma.
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Evolutionary venomics: Venom system diversification in the animal kingdom. This proposal represents a tremendous opportunity for biodiscovery from the Australian toxic fauna. This will be achieved through the researcher's unique approach of investigating previously unmapped venom systems for divergent, bioactive proteins. An understanding of venomous animal protein evolution has practical implications for the treatment of envenomations - an enormous problem in Australia - as well as great pot ....Evolutionary venomics: Venom system diversification in the animal kingdom. This proposal represents a tremendous opportunity for biodiscovery from the Australian toxic fauna. This will be achieved through the researcher's unique approach of investigating previously unmapped venom systems for divergent, bioactive proteins. An understanding of venomous animal protein evolution has practical implications for the treatment of envenomations - an enormous problem in Australia - as well as great potential in drug discovery and other commercial applications. This project will provide Australian graduate and post-graduate students with finely tuned skills in cutting edge methodological techniques and a fluent understanding of molecular evolution, preparing them to be internationally competitive scientists.Read moreRead less
Convergent Evolution of Desert Lizards: Phylogenomic and Morphological Analyses of Limb Development. Evolutionary convergence, where similar traits evolve independently in multiple lineages, is a fundamental biological process, which affects many aspects of an organism's morphology. Despite its importance we don't understand what underlies the convergence we observe in nature - does convergence in genetic make-up underlie convergence in morphology? We will investigate whether similar hindlimb mo ....Convergent Evolution of Desert Lizards: Phylogenomic and Morphological Analyses of Limb Development. Evolutionary convergence, where similar traits evolve independently in multiple lineages, is a fundamental biological process, which affects many aspects of an organism's morphology. Despite its importance we don't understand what underlies the convergence we observe in nature - does convergence in genetic make-up underlie convergence in morphology? We will investigate whether similar hindlimb morphologies are determined by the same genetic mechanisms in iguanian lizards of Australia and North America. Our study will be the first of its kind in vertebrates and will provide significant information about the evolutionary link between an animal's morphology and its genetic make-up.Read moreRead less
Environmental influence on evolutionary processes in bacterial populations. Bacterial populations exhibit remarkable adaptive capabilities in many environmental and medical settings. They respond to environmental stress in terms of altered gene expression, but what are the effects on mutation rates and fitness when cells grow at suboptimal growth rates? We plan to test whether the physiological state of an ancestral population is a determinant of a population's subsequent response to selection. ....Environmental influence on evolutionary processes in bacterial populations. Bacterial populations exhibit remarkable adaptive capabilities in many environmental and medical settings. They respond to environmental stress in terms of altered gene expression, but what are the effects on mutation rates and fitness when cells grow at suboptimal growth rates? We plan to test whether the physiological state of an ancestral population is a determinant of a population's subsequent response to selection. A simple model system using controlled culture conditions will be used to investigate the linkage between environment, mutation rate and fitness under selection. Demonstration of these linkages will have significant impacts on microbiology and understanding evolution.Read moreRead less
Stocking of fish and prawns at ecologically determined densities into Australian estuaries. Increasing numbers of people like to go fishing, and to catch a fish, which translates into tourism income and aquaculture business. Restocking is a fisheries management option when the natural supply or survival of larvae is limited. This study will determine for the first time the ecologically appropriate abundance of small mulloway and prawns that an estuary can sustain. We will assess the extra eff ....Stocking of fish and prawns at ecologically determined densities into Australian estuaries. Increasing numbers of people like to go fishing, and to catch a fish, which translates into tourism income and aquaculture business. Restocking is a fisheries management option when the natural supply or survival of larvae is limited. This study will determine for the first time the ecologically appropriate abundance of small mulloway and prawns that an estuary can sustain. We will assess the extra effort needed to release larvae into particular key habitats, and develop new technologies to identify our larvae from the wild. Our findings will be relevant to restocking of Australia's inland rivers, which at present has little ecological basis.Read moreRead less
Sex, parthenogenesis and adaptation: a novel laboratory 'natural selection' experiment testing the adaptive significance of sexual and asexual reproduction. One of the greatest challenges for evolutionary biology is explaining the widespread occurrence of sexual reproduction. Many theoretical models show some inherent benefits of sex, however these models make assumptions that little or no empirical data exists for. Using a novel phenomenon found in the parasitoid wasp genus Trichogramma, I will ....Sex, parthenogenesis and adaptation: a novel laboratory 'natural selection' experiment testing the adaptive significance of sexual and asexual reproduction. One of the greatest challenges for evolutionary biology is explaining the widespread occurrence of sexual reproduction. Many theoretical models show some inherent benefits of sex, however these models make assumptions that little or no empirical data exists for. Using a novel phenomenon found in the parasitoid wasp genus Trichogramma, I will investigate the adaptive significance of sexual and asexual reproduction in a laboratory natural selection experiment and therefore directly test the theory for the evolution and maintenance of sex. This will be the first such test in a higher organism.Read moreRead less
Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnol ....Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnology, bioremediation, and synthetic biology where evolution can be inhibited or exploited, respectively.Read moreRead less
Ancient DNA as a tool to study Australia's paleome: exploring climatic change, past biodiversity, extinctions and long-term survival of DNA. Restoration of Australian ecosystems can only occur if we know what plants, animals and insects used to live in the area before 'pest' species were introduced. This project will use ancient DNA obtained from 'poo' and cave sediments, that is thousands of years old, to discover what species used to live where and when. The ancient DNA profiles of past ecosys ....Ancient DNA as a tool to study Australia's paleome: exploring climatic change, past biodiversity, extinctions and long-term survival of DNA. Restoration of Australian ecosystems can only occur if we know what plants, animals and insects used to live in the area before 'pest' species were introduced. This project will use ancient DNA obtained from 'poo' and cave sediments, that is thousands of years old, to discover what species used to live where and when. The ancient DNA profiles of past ecosystems will allow us to make better decisions when trying to establish sustainable and 'natural' mainland and island sanctuaries. Ancient DNA is well preserved in some dry environments; this project will assess DNA preservation from sites all across Australia and use the DNA sequences to discover information about extinct animals and how past climate changes effected the native biota.Read moreRead less