Characterising Post Stroke Neuroplasticity In Humans – Identifying A Critical Window For Rehabilitation
Funder
National Health and Medical Research Council
Funding Amount
$764,419.00
Summary
Despite major investment in care for stroke patients, almost all have persisting disability. Stroke causes loss of brain cells that cannot be replaced. Some recovery is possible through compensatory mechanisms. In addition, intact cells around the stroke undergo growth that is critical for recovery. Animal studies suggest these changes take place in a “critical window” after stroke. Applying therapies in this window should improve outcomes. We will use novel approaches to define the “critical wi ....Despite major investment in care for stroke patients, almost all have persisting disability. Stroke causes loss of brain cells that cannot be replaced. Some recovery is possible through compensatory mechanisms. In addition, intact cells around the stroke undergo growth that is critical for recovery. Animal studies suggest these changes take place in a “critical window” after stroke. Applying therapies in this window should improve outcomes. We will use novel approaches to define the “critical window” in patients after strokeRead moreRead less
A New Clinical Tool To Assess Fitness-to-drive In Obstructive Sleep Apnea
Funder
National Health and Medical Research Council
Funding Amount
$727,963.00
Summary
Obstructive sleep apnoea (OSA) affects 1 in 4 middle aged adults. OSA results in impaired neurobehavioral function, excessive sleepiness, and more than 2-fold increased motor vehicle crash risk and workplace accidents. However, not all patients are impaired and identifying patients at risk is a daily clinical challenge. This project proposes new and simple measures that can accurately identify patients with OSA who are most vulnerable to alertness failure and motor vehicle accident risk.
Improving eyewitness identification accuracy using free-report lineups. There is major national and community interest in the successful conduct of criminal investigations. This research addresses the accuracy of eyewitness identification tests. Specifically, we investigate whether developing lineup procedures that separate out witnesses who are unsure of their response will prevent erroneous identifications. Progress on this issue makes an important contribution to decisions about the ideal lin ....Improving eyewitness identification accuracy using free-report lineups. There is major national and community interest in the successful conduct of criminal investigations. This research addresses the accuracy of eyewitness identification tests. Specifically, we investigate whether developing lineup procedures that separate out witnesses who are unsure of their response will prevent erroneous identifications. Progress on this issue makes an important contribution to decisions about the ideal lineup procedure, thereby preventing innocent people from being prosecuted and perpetrators being free to re-offend. Additionally the international collaboration on the project will increase the visibility of Australian social science research and provide crucial development opportunities for young Australian scientists.Read moreRead less
Identifying the bad guy with deadlined confidence judgments. There is major interest in the successful conduct of criminal investigations. Identity tests are commonly used in such investigations, but eyewitness decision accuracy is still unacceptably low. While eyewitness memory research has already contributed significantly to the development of procedures that improve the diagnosticity of identification decisions, our proposal offers radical new alternatives that can significantly improve diag ....Identifying the bad guy with deadlined confidence judgments. There is major interest in the successful conduct of criminal investigations. Identity tests are commonly used in such investigations, but eyewitness decision accuracy is still unacceptably low. While eyewitness memory research has already contributed significantly to the development of procedures that improve the diagnosticity of identification decisions, our proposal offers radical new alternatives that can significantly improve diagnosticity. In refining and evaluating these alternatives we will boost the profile of Australian science research and provide rich international training environments for young Australian and overseas scientists.Read moreRead less
Interviewing eyewitnesses: Enhancing output quantity and diagnosing accuracy. Although there has been general international agreement that open-ended police interviews (e.g., the Cognitive Interview) enhance output quantity and accuracy, it is also well documented that police investigators often depart from these procedures in order to probe for additional information. An approach to eyewitness interviewing that allows police to elicit greater detail while able to assess likely accuracy not only ....Interviewing eyewitnesses: Enhancing output quantity and diagnosing accuracy. Although there has been general international agreement that open-ended police interviews (e.g., the Cognitive Interview) enhance output quantity and accuracy, it is also well documented that police investigators often depart from these procedures in order to probe for additional information. An approach to eyewitness interviewing that allows police to elicit greater detail while able to assess likely accuracy not only has the potential to be widely adopted but would also provide a major breakthrough in the investigation of crimes and other incidents where interview data are so critical. This in turn would further enhance the profile of Australian (and UK) forensic science.Read moreRead less
Uncovering the processes underlying human category learning. There is a pervasive belief that complex tasks can somehow be learned via a 'smart' implicit or procedural learning mechanism, which operates independently of memory and attention. This idea has important implications for our understanding of cognition. If true, there seems little point in providing explicit instruction in such tasks, and efforts to do so are, at best, wasted time and, at worst, detrimental to the learning process. Th ....Uncovering the processes underlying human category learning. There is a pervasive belief that complex tasks can somehow be learned via a 'smart' implicit or procedural learning mechanism, which operates independently of memory and attention. This idea has important implications for our understanding of cognition. If true, there seems little point in providing explicit instruction in such tasks, and efforts to do so are, at best, wasted time and, at worst, detrimental to the learning process. This project will provide much-needed scrutiny of this idea and will help not only to re-orient our understanding of how we deal with complex information, but will also highlight issues about data interpretation that are fundamental for the research and wider communities.Read moreRead less
I am a molecular geneticist with a main research focus in the identification and characterisation of genes and molecular pathways involved in intellectual disability and epilepsy.
Eyewitness identification: Metacognitive influences on choosing behaviour. There is major national and community interest in the successful conduct of criminal investigations. This research addresses the two most significant problems associated with the conduct of eyewitness identification tests: mistaken identifications of innocent suspects and failure to identify guilty suspects when they are present in the lineup. Progress on the latter problem - which results in offenders avoiding detection ....Eyewitness identification: Metacognitive influences on choosing behaviour. There is major national and community interest in the successful conduct of criminal investigations. This research addresses the two most significant problems associated with the conduct of eyewitness identification tests: mistaken identifications of innocent suspects and failure to identify guilty suspects when they are present in the lineup. Progress on the latter problem - which results in offenders avoiding detection - would be a major contribution with national impact. As well as the obvious implications for the conduct of lineups, the international collaboration on the project will increase the visibility of Australian social science research and provide crucial development opportunities for young Australian scientists.Read moreRead less
Can attentional re-training reduce food cravings and consumption? This project aims to determine the impact of a procedure involving the re-training of attention to food cues on food cravings and food intake. Results will advance our understanding of food cravings and contribute to interventions aimed at curbing unwanted cravings and (over) consumption.
Are two processes one too many? An investigation of the viability of the dual-process model of recognition memory. Memory is the glue that holds together our lives and personal identities. While psychologists are developing better and more sophisticated accounts of how it works, many deep questions remain. The present research examines some of these questions in relation to how memory can be decomposed into its component processes and how we are to understand these processes. An appropriate unde ....Are two processes one too many? An investigation of the viability of the dual-process model of recognition memory. Memory is the glue that holds together our lives and personal identities. While psychologists are developing better and more sophisticated accounts of how it works, many deep questions remain. The present research examines some of these questions in relation to how memory can be decomposed into its component processes and how we are to understand these processes. An appropriate understanding of these questions is vital to the development of interventions (both psychological and pharmacological) designed to halt or even reverse memory decline associated with normal aging and age-associated brain disease (such as Alzheimer disease).Read moreRead less