Sustainable copper metallurgy and recycling – saving energy and resources. This project aims to develop new, powerful and sophisticated, computer-based models that can reliably predict the results of chemical reactions in complex, high temperature metal production processes. This project expects to use these models, initially applied to copper smelting systems, to enable the improved recycling of other valuable metals. These models should be able to be applied to a wide range of technologies use ....Sustainable copper metallurgy and recycling – saving energy and resources. This project aims to develop new, powerful and sophisticated, computer-based models that can reliably predict the results of chemical reactions in complex, high temperature metal production processes. This project expects to use these models, initially applied to copper smelting systems, to enable the improved recycling of other valuable metals. These models should be able to be applied to a wide range of technologies used in the metallurgical industry as most of the world’s metals are produced by these pyrometallurgical processes. This should provide significant benefits such as substantial improvements in productivity and process efficiencies, whilst at the same time delivering energy savings and improved use of valuable metal resources.Read moreRead less
Creating wealth from new resources - High temperature extraction of metals from complex copper ores and recycled materials. Most of the world’s copper is produced using high temperature chemical processing (smelting). Both primary ores and recycled raw materials contain valuable elements and also potentially harmful impurity elements. To unlock and utilise current and new resources, and also minimise the environmental impacts the industry has identified the need for new fundamental scientific da ....Creating wealth from new resources - High temperature extraction of metals from complex copper ores and recycled materials. Most of the world’s copper is produced using high temperature chemical processing (smelting). Both primary ores and recycled raw materials contain valuable elements and also potentially harmful impurity elements. To unlock and utilise current and new resources, and also minimise the environmental impacts the industry has identified the need for new fundamental scientific data that describe the chemical behaviour of impurity elements in these systems. The project aims to then use the data to develop powerful computer-based thermodynamic models that can predict the products of complex industrial processes. These sophisticated tools are intended to then be used to improve the performance of existing industrial operations and assist in the development of new process designs.Read moreRead less
Future polymetallic processing through lead smelting, recycling, refining. The aim of the project is to provide new data and thermodynamic modelling tools to be used in the development of the next generation of lead metal smelting, refining and recycling processes used to recycle electronic materials, process hazardous wastes and recover valuable metals. The intention is to combine recently developed experimental techniques with the latest advances in FactSage chemical thermodynamic modelling to ....Future polymetallic processing through lead smelting, recycling, refining. The aim of the project is to provide new data and thermodynamic modelling tools to be used in the development of the next generation of lead metal smelting, refining and recycling processes used to recycle electronic materials, process hazardous wastes and recover valuable metals. The intention is to combine recently developed experimental techniques with the latest advances in FactSage chemical thermodynamic modelling to overcome long-standing experimental and modelling obstacles. The new experimental data and databases are intended to provide important information on high-temperature chemistry of complex phase equilibria and on the distribution of minor elements in multiphase systems.Read moreRead less
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhi ....Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhibit myopia, with the aim of determining an ocular measure that is related to myopia, which is altered by drugs that are known to slow myopia progression, and that could be used as an indication of an agent's likely effectiveness.Read moreRead less
Enhancing Direct Cu Recovery through Increased Gas Processing Understanding. This project aims to investigate mechanisms of copper loss during smelting and find new ways to reduce the loss. Smelting, which produces copper matte product and slag tailings, is an important step of the copper-making process from copper sulphides. The loss of copper to slag can be as high as 12 per cent. The project aims to create new knowledge about copper loss by matte droplets floated with gas bubbles generated by ....Enhancing Direct Cu Recovery through Increased Gas Processing Understanding. This project aims to investigate mechanisms of copper loss during smelting and find new ways to reduce the loss. Smelting, which produces copper matte product and slag tailings, is an important step of the copper-making process from copper sulphides. The loss of copper to slag can be as high as 12 per cent. The project aims to create new knowledge about copper loss by matte droplets floated with gas bubbles generated by chemical reactions to the slag phase. The outcomes are intended to enable copper smelters to maximise direct copper recovery, reduce copper production costs and increase the productivity of the smelting process.Read moreRead less
Improvements in Australia’s iron ore resource utilisation . This project aims to support improved extraction and utilisation of Australia’s iron ore resources through providing new technical information on the behaviour of the ores during iron ore sintering. The project will measure the rates of chemical reactions taking place between the minerals and high temperature melts encountered in iron ore sintering. These reactions are critical in determining the microstructures formed and the resulting ....Improvements in Australia’s iron ore resource utilisation . This project aims to support improved extraction and utilisation of Australia’s iron ore resources through providing new technical information on the behaviour of the ores during iron ore sintering. The project will measure the rates of chemical reactions taking place between the minerals and high temperature melts encountered in iron ore sintering. These reactions are critical in determining the microstructures formed and the resulting physical properties of the iron ore sinter. Understanding the effect of these properties on subsequent iron -making process efficiency will support companies to efficiently use, market, and sell different iron ores.Read moreRead less
Systematic evaluation of whether in vitro methods can predict in vivo opioid analgesic efficacy, safety and tolerability. It is estimated that chronic pain affects one in five individuals in the general community in Australia and worldwide, with prevalence rates correlated directly with advancing age. Chronic pain not only adversely affects the quality of life of individuals but it also places a large economic burden on our healthcare system. Development and validation of an in vitro method to ....Systematic evaluation of whether in vitro methods can predict in vivo opioid analgesic efficacy, safety and tolerability. It is estimated that chronic pain affects one in five individuals in the general community in Australia and worldwide, with prevalence rates correlated directly with advancing age. Chronic pain not only adversely affects the quality of life of individuals but it also places a large economic burden on our healthcare system. Development and validation of an in vitro method to successfully identify novel morphine-like strong analgesics with a reduced propensity for producing respiratory depression or constipation, has the potential to not only improve pain management for individuals and to reduce the economic burden of chronic pain on the Australian healthcare system, but it is also likely to produce direct economic benefits to our nation. Read moreRead less
New modulators of voltage-gated sodium channel subtypes from Australian Tarantula venoms. The venoms of Australian tarantula spiders provide a unique and untapped source of bioactive molecules. From a large stock of venom, and in collaboration with Australian pharmaceutical company Xenome, we will develop a comprehensive library of venom components suitable for drug screening. Potential national benefits from this work include a huge reduction in the healthcare bill deriving from a new treatmen ....New modulators of voltage-gated sodium channel subtypes from Australian Tarantula venoms. The venoms of Australian tarantula spiders provide a unique and untapped source of bioactive molecules. From a large stock of venom, and in collaboration with Australian pharmaceutical company Xenome, we will develop a comprehensive library of venom components suitable for drug screening. Potential national benefits from this work include a huge reduction in the healthcare bill deriving from a new treatment for pain, as well as substantial royalty returns from drugs sales. Discoveries from the program are also likely to lead to an enhancement in Australia's reputation in the neurosciences and to the development of new diagnostic research tools. The major community benefit will be a reduction in the suffering of chronic pain patients.Read moreRead less
Development of a novel process for recovering fluoride from spent pot-lining as AlF2(OH) using industrial waste solutions. Every year approximately 40,000 tonnes of a hazardous waste known as spent pot-lining is generated by Australia’s aluminium industry. It contains significant levels of leachable cyanide and fluoride and is currently being stored awaiting a suitable treatment technology. This project will develop a novel low-energy and low-cost process for extracting the fluoride as a usefu ....Development of a novel process for recovering fluoride from spent pot-lining as AlF2(OH) using industrial waste solutions. Every year approximately 40,000 tonnes of a hazardous waste known as spent pot-lining is generated by Australia’s aluminium industry. It contains significant levels of leachable cyanide and fluoride and is currently being stored awaiting a suitable treatment technology. This project will develop a novel low-energy and low-cost process for extracting the fluoride as a useful aluminium fluoride product that can be recycled back into the aluminium industry; destroy the cyanide; and recover other components for use in the metallurgical industry. If commercialised the benefit will be an end to the stockpiling of spent pot-lining in Australia, a more sustainable aluminium industry, and protection of the world’s natural fluoride resources.Read moreRead less